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Methamphetamine

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Definition: A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.  a CNS stimulant; smokable crystal methamphetamine, called "ice" by drug abusers, goes here   
Pharmacological Action Adrenergic Agents; Adrenergic Uptake Inhibitors; Central Nervous System Stimulants; Dopamine Agents; Dopamine Uptake Inhibitors; Sympathomimetics
Examples Benzphetamine 		Other names Deoxyephedrine; N Methylamphetamine; Hydrochloride, Methamphetamine; N-Methylamphetamine; Methylamphetamine; Methamphetamine Hydrochloride; Metamfetamine; Madrine; Langly Brand of Methamphetamine Hydrochloride; Desoxyn; Desoxyephedrine; Abbott Brand of Methamphetamine HydrochlorideDrugs* : METHAMPHETAMINE HYDROCHLORIDE; METHAMPEX; DESOXYN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
mephedrone  0   Methamphetamine/*analogs & derivatives Street Drugs Designer Drugs. BMJ. 2010;340() (dup#51):c1605
4-hydroxy-3-methoxymethamphetamine glucuronide  0   *Glucuronides Methamphetamine/*analogs & derivatives. Chem Pharm Bull (Tokyo). 2009 May;57(5):472-5
N-ethylmethamphetamine  0   Methamphetamine/*analogs & derivatives. Forensic Sci Int 2004 Aug 11;144(1):29-36
methylone  0   Methamphetamine/*analogs & derivatives. Eur J Pharmacol 1999 Sep 17;381(1):63-9
beta,beta-difluoromethamphetamine  0   Methamphetamine/*analogs & derivatives Carbon Radioisotopes. Appl Radiat Isot 1999 Apr;50(4):707-14
methamphetamine hydroxylamine  0   *Hydroxylamines Methamphetamine/*analogs & derivatives. J Pharm Exp Ther 1999 Mar;288(3):1251-60
paramethoxymethamphetamine  0   Methamphetamine/*analogs & derivatives. Pharmacol Biochem Behav 1997 May-Jun;57(1-2):151-8
N-acetylmethamphetamine  0   Methamphetamine/*analogs & derivatives. J Forensic Sci 1996 Jul;41(4):645-7
4-allyloxymethamphetamine  0   Methamphetamine/*analogs & derivatives Cytochrome P-450 Enzyme System/antagonists & inhibitors. J Pharmacol Exp Ther 1996 May;277(2):595
4-hydroxydesmethylfamprofazone  0   *Pyrazoles Methamphetamine/*analogs & derivatives. J Chromatogr B Biomed Appl 1994 Nov 18;661(2):255-61
1-fluoro-1-deoxyephedrine  161403-39-0   Methamphetamine/*analogs & derivatives Fluorine Radioisotopes. J Med Chem 1995 Mar 3;38(5):810-5
4-hydroxy-3-methoxymethamphetamine  117652-28-5   Methamphetamine/*analogs & derivatives. J Pharm Biomed Anal 1992 Sep;10(9):657-65
3-methoxy-4-methylamphetamine  124206-66-2   Methamphetamine/*analogs & derivatives. Mol Pharmacol 1993 Feb;43(2):271-6
famprofazone  22881-35-2   *Pyrazolones Methamphetamine/*analogs & derivatives. Xenobiotica 1992 Mar;22(3):377-84
2,4,5-trihydroxymethamphetamine  136706-32-6   Methamphetamine/*analogs & derivatives Neurotoxins. Chem Res Toxicol 1991 Nov-Dec;4(6):626-32
chlormethamphetamine  1199-85-5   Methamphetamine/*analogs & derivatives.
4-methoxymethamphetamine  22331-70-0   Methamphetamine/*analogs & derivatives. Pharmacol Biochem Behav 1989;31(1):9
pholedrine sulfuric acid ester  114860-09-2   Methamphetamine/*analogs & derivatives. Pharmazie 1988;43(2):135
N-hydroxymethamphetamine  52271-36-0   Methamphetamine/*analogs & derivatives. Xenobiotica 1987;17(9):1029
O-desmethylmethoxyphenamine  582-43-4 Phenol, 2-(2-(methylamino)propyl)-, (1R)  Methamphetamine/*analogs & derivatives. J Chromatogr 1984;310(2):307
5-hydroxymethoxyphenamine  61866-76-0 Phenol, 4-methoxy-3-(2-(methylamino)propyl)-, (Z)  Methamphetamine/*analogs & derivatives. J Chromatogr 1984;310(2):307
N-nitrosomethamphetamine  86022-93-7   Methamphetamine/*analogs & derivatives. Cancer Lett 1983;21(1):63
2-bromomethamphetamine  4302-94-7   Methamphetamine/*analogs & derivatives. Acta Physiol Acad Sci Hung 1981;57(3):285
N-methylphenethylamine  589-08-2   Methamphetamine/*analogs & derivatives. Biochem Pharmacol 1980;29(19):2663
norfenefrine, pholedrine drug combination  0   Drug Combinations Methamphetamine/*analogs & derivatives 2-Hydroxyphenethylamine/*analogs & derivatives. Fortschr Med 96(19):1046;1978
Metamin-Hippurate  0   *Hippurates *Methamphetamine Drug Combinations. Nord Med 92(1):9;1977
adamantylmethamphetamine  56558-34-0 2-methylamino-1-(adamant-1'-yl)propane  Adamantane/*analogs & derivatives Methamphetamine/*analogs & derivatives. Farmaco(Ed Prat) 31(5):227;1976
4-bromomethamphetamine  4302-85-6   Methamphetamine/*analogs & derivatives. Pol J Pharmacol Pharm 27(suppl):91;1975; Pol J Pharmacol Pharm 29(5):247;1977
N,alpha,alpha'-trimethyldiphenethylamine  53660-19-8 N,alpha-dimethyl-N-(1-methyl-2-phenylethyl)benzeneethanamine  Methamphetamine/*analogs & derivatives. J Pharm Sci 63(10):1575;1974; JAOA 57(5):1147;1974
N-formylmethamphetamine  42932-20-7 Formamide, N-methyl-N-(1-methyl-2-phenylethyl)  Methamphetamine/*analogs & derivatives. J AOAC 57(5):1147;1974
alpha-benzyl-N-methylphenethylamine  53660-20-1   Methamphetamine/*analogs & derivatives. J AOAC 57(5):1147;1974
N-(4-aminobutyl)methamphetamine  78232-38-9 1,4-Butanediamine, N-methyl-N-(1-methyl-2-phenylethyl)-, (S)  Methamphetamine/*analogs & derivatives. FEBS Lett 36(3):339;1973
pholedrine  370-14-9 4-(2-(methylamino)propyl)phenol  Methamphetamine/*analogs & derivatives.
Pharma Action Central Nervous System Stimulants ; Sympathomimetics 		Drug Alcohol Depend 1(6):381;1976; Pharmazie 30(11):720;1975; Pharmazie 33(1):87;1978; Z Gynaekology 100(6):381;1978
methoxyphenamine  93-30-1   Methamphetamine/*analogs & derivatives.
Pharma Action Adrenergic beta-Agonists 		Boll Chim Farm 114(4):201;1975; Clin Ter 71(4):337;1974; Drug Metab Dispos 4(6):568;1976; J Chromatogr 119:609;1976; J Chromatogr 144(2):280;1977; J Chromatogr 161:223;1978; J Pharm Pharmacol (Suppl) 28:55;1976
1,4-acetyldeoxyephedrine  34145-17-0   Methamphetamine/*analogs & derivatives. Eur J Pharmacol 22(2):121;1973
dimethylamphetamine  4075-96-1 N,N,alpha-trimethylbenzeneethanamine  Methamphetamine/*analogs & derivatives.
Pharma Action Central Nervous System Stimulants
4-nitromethylamphetamine  4302-88-9   Methamphetamine/*analogs & derivatives. Br J Pharmacol 43(4):732;1971

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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