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Methenamine

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Definition: An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)     
Pharmacological Action Anti-Infective Agents, Urinary 		Other names Hexamine; Hexamethylenetetramine; Silver, Methenamine; Silver, Hexamine; Methenamine, Silver; Urotropin; Silver Methenamine; Methenamine Silver; Hexamine Silver; Aminoform
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
geovet  130030-61-4   Methenamine Oxytetracycline. Gig Tr Prof Zabol 1990;(8):25
dentinol  0   *Bismuth *Methenamine Drug Combinations Root Canal Filling Materials. Oral Surg Oral Med Oral Pathol 1986;62(4):434
hexargin  86336-33-6 Hexargin  *Methenamine *Silver Nitrate Drug Combinations. Acta Paediatr Scand (Suppl) 1982;295:1
comethylenamine  81627-84-1   *Methenamine *Organometallic Compounds Cobalt. Farmakol Toksikol 1982;45(2):70
methenamine mandelate  587-23-5   *Mandelic Acids Methenamine/*analogs & derivatives. Clin Chim Acta 100(1):55;1980
quaternium-15  4080-31-3   Methenamine/*analogs & derivatives Preservatives, Pharmaceutical. Cutis 22(6):655;1978
methenamine hippurate  5714-73-8 hexamethylene tetramine hippurate  *Hippurates Methenamine/*analogs & derivatives.
Pharma Action Anti-Infective Agents, Urinary 		Acta Obstet Gynecol Scand 54(4):387;1975; Arch Phys Med Rehabil 1980;61(4):178; Invest Urol 15(5):367;1978; Irish Med J 69(4):97;1977METHENAMINE HIPPURATE; HIPREX; UREX
degmin  76391-82-7 1H-Azepinium, 1-(2-(decyloxy)-2-oxoethyl)-1-heptylhexahydro-, hydroxide  Methenamine/*analogs & derivatives. Farmatsiia 24(2):91;1975; Vestn Dermatol Venerol 1980;(3):55
degmicide  69597-41-7 Degmicide  Methenamine/*analogs & derivatives. Voen Med Zh 8:64;1975
rhodovet  51377-21-0   Methenamine/*analogs & derivatives. Allerg Immunol (Leipz)19(2-4):173;1973
Veryl  35482-52-1 1,3,5,7-Tetraazatricyclo(3.3.1.13,7)decane, compd. with mercury cyanide (Hg(CN)2) (1:2)  *Cyanides *Mercury *Methenamine. Farm Zh 26(6):11;1971

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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