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Methionine Adenosyltransferase

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Definition: An enzyme that catalyzes the synthesis of S-adenosylmethionine from methionine and ATP. EC 2.5.1.6.      Other names S-Adenosylmethionine Synthetase; Synthetase, S-Adenosylmethionine; S-Adenosyltransferase, ATP-Methionine; S Adenosylmethionine Synthetase; Adenosyltransferase, Methionine; ATP Methionine S Adenosyltransferase; ATP-Methionine S-Adenosyltransferase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Mat2beta protein, human  EC 2.5.1.6   *Methionine Adenosyltransferase. Hepatology 2008 Feb;47(2):521-31
MAT2A protein, human  EC 2.5.1.6   *Methionine Adenosyltransferase. Hepatology 2008 Feb;47(2):521-31
MetK protein, E coli  EC 2.5.1.6   *Methionine Adenosyltransferase *Escherichia coli Proteins. J Biol Chem 1984 Dec 10;259(23):14505-7
Mat2a protein, rat  EC 2.5.1.6   *Methionine Adenosyltransferase.
MAT1A protein, human  EC 2.5.1.6   *Methionine Adenosyltransferase. Early Hum Dev 2005 Jun;81(6):529-33
Mat1a protein, mouse  EC 2.5.1.6   *Methionine Adenosyltransferase Isoenzymes. FASEB J 2004 May;18(7):914-6
5'-((homocysteinyl)methyl)adenosine 5'-(beta,gamma-imidotriphosphate)  109214-84-8   Adenosine Triphosphate/*analogs & derivatives Methionine Adenosyltransferase/antagonists & inhibitors. J Med Chem 1987;30(9):1599
(5'-((N-triphosphoamino)methyl)adenosyl)homocysteine  101249-72-3   Adenosine Triphosphate/*analogs & derivatives Homocysteine/*analogs & derivatives Methionine Adenosyltransferase/antagonists & inhibitors. J Med Chem 1987;30(5):888
2-amino-4-methoxy-3-butenoic acid  35891-72-6   *Aminobutyric Acids Porphobilinogen Synthase/antagonists & inhibitors Aspartate Aminotransferases/antagonists & inhibitors Methionine Adenosyltransferase/antagonists & inhibitors Toxins, Biological. Biochem Biophys Res Commun 65(2):765;1975; Biochem J 176(1):335;1978; Biochem Pharmacol 1980;29(4):501; J Antibiotics 25(2):122;1972; J Biol Chem 251(11):3306;1976; J Med Chem 22(1):13;1979; Life Sci 24(2):185;1979; Nature 250(467):586;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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