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Bis-Trimethylammonium Compounds

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Definition: Compounds containing polymethylene bis-trimethylammonium cations. Members of this group frequently act as ganglionic blockers and neuromuscular depolarizing agents.  DF: METHONIUM CPDS   
Examples Decamethonium Compounds; Hexamethonium Compounds 		Other names Methonium Compounds; Bis Trimethylammonium Compounds; Bis Trimethyl Ammonium Compounds; Bis-Trimethyl-Ammonium Compounds
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1,3-bis(N,N,N-trimethylammonium)-2-propylacrylate dichloride  0   *Acrylates *Bis-Trimethylammonium Compounds. Chimia (Aarau). 2010;64(4):268
1,3-bis(N,N,N-trimethylammonium)-2-propylmethacrylate dichloride  0   *Bis-Trimethylammonium Compounds *Polymethyl Methacrylate. Chimia (Aarau). 2010;64(4):268
(2-(6-(aminomethyl)naphthalen-2-yloxy)ethyl)trimethylammonium  0   *Bis-Trimethylammonium Compounds *Naphthalenes. J Org Chem 2009 Jan 2;74(1):339-50
cethyltrimethylammonium chloride  0   *Bis-Trimethylammonium Compounds Micelles. J Colloid Interface Sci 2007 Dec 15;316(2):730-40
azamethonium compounds  0   *Bis-Trimethylammonium Compounds. Klin Med (Mosk) 1983;61(11):58
IEM 1213  0   *Bis-Trimethylammonium Compounds. Eur J Pharmacol 1994 May 12;257(1-2):1-5
proheparum  72980-85-9   *Cysteine *Inositol *Liver Extracts *Bis-Trimethylammonium Compounds *Vitamin B 12 Drug Combinations. Nippon Shokakibyo Gakkai Zasshi 1993 Nov;90(11):2945-50
dimethonium  20828-82-4   *Bis-Trimethylammonium Compounds. Am J Physiol 1985;249(5 Pt 2):H989
prolonium  123-47-7   *Bis-Trimethylammonium Compounds. Dtsch Med Wochenschr 1982;107(40):1519
1-(5-dimethylaminonaphthalene 1-sulfonamido)decane-10-trimethylammonium  68684-39-9 1-decanaminium, 10-(((5-(dimethylamino)-1-naphthalenyl)sulfonyl)amino)-N,N,N-trimethyl-, salt with (R-(R*,R*))-2,3-dihydroxybutanedioic acid (1:1)  *Bis-Trimethylammonium Compounds. Int J Pept Protein Res 1981;17(2):170
dansyl-pentane-5-trimethylammonium  68684-37-7 1-pentanaminium, 5-(((5-(dimethylamino)-1-naphthalenyl)sulfonyl)amino)-N,N,N-trimethyl-, salt with (R-(R*,R*))-2,3-dihydroxybutanedioic acid (1:1)  *Dansyl Compounds *Bis-Trimethylammonium Compounds. Int J Pept Protein Res 1981;17(2):170
dodeconium  3818-69-7 1,6-hexanediamine, N,N'-bis(2-(dodecyloxy)-2-oxoethyl)-N,N,N',N'-tetramethyl  *Bis-Trimethylammonium Compounds. Farmakol Toksikol 40(2):219;1977; Mikrobiol Zh 40(1):76;1978; Vrach Delo 1980;(3):118
pentamethonium  2365-25-5 N,N,N,N',N',N'-hexamethyl-1,5-pentanediaminium  *Bis-Trimethylammonium Compounds. Gastroenterology 72(4):720;1977
heptane-1,7-bis(dimethyl-3'-phthalimidopropylammonium)  22664-47-7 1,7-Heptanediaminium, N,N'-bis(3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl)-N,N,N',N'-tetramethyl  *Bis-Trimethylammonium Compounds *Isoindoles. Eur J Pharmacol 33(2):237;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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