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Mitogens

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Definition: Substances that stimulate mitosis and lymphocyte transformation. They include not only substances associated with LECTINS, but also substances from streptococci (associated with streptolysin S) and from strains of alpha-toxin-producing staphylococci. (Stedman, 25th ed)     
See Also Receptors, Mitogen 		Other names Phytomitogens
Substances having this pharmacologic action: Dolichos biflorus lectin receptor; polyclonal B cell activator; lipopolysaccharide B; bis(p-chlorophenyl)acetic acid; desthiobiotin; metaperiodate; trimethyllysine; Phytohemagglutinins; Pokeweed Mitogens; Concanavalin A; hepatic stimulator substance; juzentaihoto
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
AKAP12 protein, human  0   *Cell Cycle Proteins *A Kinase Anchor Proteins Mitogens.
Akap12 protein, mouse  0   *Cell Cycle Proteins *A Kinase Anchor Proteins Mitogens.
hOKT3 gamma4  0   *Muromonab-CD3 Mitogens. Cancer Res 1999 May 1;59(9):2096-101
ypmB protein, Yersinia pseudotuberculosis  0   *Bacterial Proteins Mitogens Superantigens. FEBS Lett 1997 Aug 11;413(1):174-6
Streptococcus pyogenes mitogen-2  0   *Bacterial Proteins Antigens, Bacterial Mitogens Superantigens. Immunology 1997 Jul;91(3):406-13
Akap12 protein, rat  0   *Cell Cycle Proteins *A Kinase Anchor Proteins Mitogens. J Biol Chem 1996 Nov 8;271(45):28430-8
Nocardia delipidated cell mitogen  0   Organic Chemicals Mitogens. Folia Microbiol (Praha) 1995;40(4):417-20
RET protein, human  EC 2.7.1.112   *Proto-Oncogene Proteins c-ret Mitogens. Mol Cell Biol 1996 May;16(5):2151-63
Yersinia pseudotuberculosis-derived mitogen  0   *Bacterial Proteins Antigens, Bacterial Mitogens Superantigens. J Immunol 1995 May 15;154(10):5228-34
Mycoplasma arthritidis mitogen  0   *Antigens, Bacterial *Superantigens Mitogens Superantigens. J Immunol 1987;139(3):927
bryostatin 1  83314-01-6   *Bryostatins Enzyme Activation Mitogens.
Pharma Action Adjuvants, Immunologic ; Antineoplastic Agents 		Biochem Biophys Res Commun 1985;131(3):1109
vesiculogen  72994-03-7   *Fungal Proteins Mitogens. Microbiol Immunol 23(10):997;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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