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Muscle Relaxants, Central

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Definition: A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)  refers to skeletal muscle relaxants only: smooth muscle relaxants   
See Also Parasympatholytics
Other names Centrally Acting Muscle Relaxants; Relaxants, Central Muscle; Central Muscle Relaxants
Substances having this pharmacologic action: tizanidine; eperisone; afloqualone; bendazole; cyclobenzaprine; tetrazepam; Diazepam; Chlormezanone; Chlorphenesin; Chlorzoxazone; Quinine; Tolperisone; Xylazine; Zoxazolamine; Orphenadrine; Medazepam; Mephenesin; Meprobamate; Methocarbamol; Baclofen; Carisoprodol; Dantrolene; Y 27632; HOE 234; GYKI 52466; chlorproethazine

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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