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N-Acetylmuramoyl-L-alanine Amidase

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Definition: An autolytic enzyme bound to the surface of bacterial cell walls. It catalyzes the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell wall glycopeptides, particularly peptidoglycan. EC 3.5.1.28.      Other names Mucopeptide Amidohydrolase; N Acetylmuramoyl L alanine Amidase; Lysozyme, T7; LE Enzyme; Hydrolase, Peptidoglycan; Hydrolase, Murein; Endolysin, T7; Amidohydrolase, Mucopeptide; Amidase, N-Acetylmuramoyl-L-alanine; T7 Lysozyme; T7 Endolysin; Peptidoglycan Hydrolase; Murein Hydrolase; LE-Enzyme; Autolysin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Auto autolysin, Listeria monocytogenes  EC 3.5.1.28   *Bacterial Proteins *Membrane Proteins *N-Acetylmuramoyl-L-alanine Amidase. Mol Microbiol 2004 Mar;51(6):1601-14
PlyG lysin, gamma phage  EC 3.-   *N-Acetylmuramoyl-L-alanine Amidase *Viral Proteins Peptidoglycan. Nature 2002 Aug 22;418(6900):884-9
LytC protein, Streptococcus  EC 3.5.1.-   *N-Acetylmuramoyl-L-alanine Amidase. Res Microbiol. 2000 Jul-Aug;151(6):435-43
CwlH protein, Bacillus subtilis  EC 3.5.1.28   *Bacterial Proteins *N-Acetylmuramoyl-L-alanine Amidase. J Bacteriol 1999 Oct;181(20):6230-7
LytB protein, Streptococcus  EC 3.5.1.-   *N-Acetylmuramoyl-L-alanine Amidase. Mol Microbiol 1999 Feb;31(4):1275-81
PLYTW protein, Staphylococcus phage Twort  EC 3.5.1.28   *N-Acetylmuramoyl-L-alanine Amidase *Viral Proteins. FEMS Microbiol Lett 1998 May 15;162(2):256-74
LytE protein, Bacillus subtilis  EC 3.5.1.28   *Bacterial Proteins *N-Acetylmuramoyl-L-alanine Amidase. J Bacteriol 1998 May;180(9):2549-55
LytH protein, Staphylococcus aureus  EC 3.5.1.28   *Bacterial Proteins *N-Acetylmuramoyl-L-alanine Amidase Drug Resistance, Microbial. J Bacteriol 1997 Oct;179(20):6294-301
CwlD protein, Bacillus subtilis  EC 3.5.1.28   *Bacterial Proteins *N-Acetylmuramoyl-L-alanine Amidase. J Bacteriol 1995 Oct;177(19):5582-9
CwlL protein, Bacillus licheniformis  EC 3.5.1.28   *Bacterial Proteins *N-Acetylmuramoyl-L-alanine Amidase. Mol Gen Genet 1993 Nov;241(3-4):380-8
cwlC protein, Bacillus subtilis  EC 3.-   *Bacterial Proteins *N-Acetylmuramoyl-L-alanine Amidase. J Bacteriol 1993 Oct;175(19):6260-8
EJL amidase  EC 3.5.1.-   *N-Acetylmuramoyl-L-alanine Amidase. J Bacteriol 1992 Sep;174(17):5516-25
AmpD protein, Bacteria  EC 3.5.1.28   *Bacterial Proteins *N-Acetylmuramoyl-L-alanine Amidase. Mol Microbiol 1989;3(8):1091
L-11 cell wall lytic enzyme  0   *Multienzyme Complexes *N-Acetylmuramoyl-L-alanine Amidase *Endopeptidases. Arch Oral Biol 1979;24(7):529

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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