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NADH Dehydrogenase

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Definition: A flavoprotein and iron sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. In eukaryotes the enzyme can be found as a component of mitochondrial electron transport complex I. Under experimental conditions the enzyme can use CYTOCHROME C GROUP as the reducing cofactor. The enzyme was formerly listed as EC 1.6.2.1.  do not confuse with NADPH DEHYDROGENASE; do not confuse X ref NADH CYTOCHROME C REDUCTASE with NADPH CYTOCHROME C REDUCTASE    Other names NADH Cytochrome c Reductase; Dehydrogenase, NADH; NADH Cytochrome c Oxidoreductase; NADH (Acceptor) Oxidoreductase; Diaphorase (NADH Dehydrogenase)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NAD7 protein, Arabidopsis  EC 1.6.99.3   *NADH Dehydrogenase *Arabidopsis Proteins Protein Subunits. J Biol Chem 2011 Jun 17;286(24):21361-71
ndhG protein, Arabidopsis  EC 1.6.99.3   *NADH Dehydrogenase *Arabidopsis Proteins Protein Subunits. Plant J. 2010 Jan;61(2):339-49
ND5 protein, mouse  EC 1.6.99.3   *NADH Dehydrogenase *Mitochondrial Proteins Protein Subunits. Hum Mol Genet 2009 May 1;18(9):1578-89
1-hydroxy-2-dodecyl-4(1H)quinolone  0   *Quinolones NADH Dehydrogenase/antagonists & inhibitors. Antimicrob Agents Chemother 2007 Apr;51(4):1217-22
NADH dehydrogenase subunit 2, human  EC 1.6.99.3   *NADH Dehydrogenase. Hypertens Res 2007 Mar;30(3):213-8
NADH dehydrogenase subunit 1, human  EC 1.6.99.3   *NADH Dehydrogenase. Diabetes Res Clin Pract 2006 Jul;73(1):77-82
NDUFA3 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Mol Vis 2006;12 (dup#7):384-8
NDUFA5 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Cytogenet Cell Genet 1999;84(1-2):125-7
NADH dehydrogenase subunit 6, mouse  EC 1.6.99.3   *NADH Dehydrogenase. Mol Cell Biol 2006 Feb;26(3):1077-86
MT-ND6 protein, human  EC 1.6.99.3   *NADH Dehydrogenase. FEBS Lett 2005 Dec 19;579(30):6909-13
NDUFAF1 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. FEBS J 2005 Oct;272(20):5317-26
mt-Nd2 protein, mouse  EC 1.6.5.3   *NADH Dehydrogenase. Diabetologia 2005 Feb;48(2):261-7
NDUFS2 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Biochim Biophys Acta 2004 Dec 6;1659(2-3):136-47
NDUFS7 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Biochim Biophys Acta 2004 Dec 6;1659(2-3):136-47
NDUFS6 protein, human  EC 1.6.99.3   *NADH Dehydrogenase. J Clin Invest 2004 Sep;114(6):837-45
NDUFV2 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Eur J Biochem. 2004 Sep;271(17):3588-95
mt-Nd1 protein, rat  EC 1.6.5.3   *NADH Dehydrogenase.
mt:ND1 protein, Drosophila  EC 1.6.5.3   *NADH Dehydrogenase *Drosophila Proteins.
NdhF protein, plant  EC 1.6.99.-   *NADH Dehydrogenase *Plant Proteins.
NDUFS1 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Cell. 2004 Jun 11;117(6):773-86
NuoL protein, E coli  EC 1.6.2.1   *NADH Dehydrogenase *Escherichia coli Proteins Protein Subunits. J Biol Chem 2003 Oct 31;278(44):43114-20
NuoM protein, E coli  EC 1.6.2.1   *NADH Dehydrogenase *Escherichia coli Proteins. J Biol Chem 2003 Jul 11;278(28):25731-7
NDUFS3 protein, human  EC 1.6.5.3   *NADH Dehydrogenase.
GAS-1 protein, C elegans  EC 1.6.5.3   *NADH Dehydrogenase *Caenorhabditis elegans Proteins. Anesthesiology 1999 Feb;90(2):545-54
NDUFS4 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Hum Mol Genet 2001 Mar 1;10(5):529-35
NDUFB9 protein, human  EC 1.6.5.3   *NADH Dehydrogenase Branchio-Oto-Renal Syndrome. Hum Hered 1999 Mar;49(2)75-80:75-80
NDUFA1 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Proc Natl Acad Sci U S A 1999 Apr 13;96(8):4354-9
NDUFA8 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Hum Genet 1998 Nov;103(5):557-63
NDUFS8 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Gene 1998 Jul 17;215(1):1-10
NDUFV1 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Biochem Biophys Res Commun 1998 Apr 17;245(2):599-606
NADH dehydrogenase subunit 4  EC 1.6.5.3   *NADH Dehydrogenase Drosophila Proteins. Curr Genet 1995 Nov;28(6):553-9
MT-ND1 protein, human  EC 1.6.5.3   *NADH Dehydrogenase. Mol Phylogenet Evol 1995 Sep;4(3):235-46
NADH dehydrogenase II  EC 1.6.99.-   *NADH Dehydrogenase Escherichia coli Proteins. Mol Microbiol 1994 May;12(3):433-44
NdhF protein, bacteria  EC 1.6.99.-   *Bacterial Proteins *NADH Dehydrogenase. J Bacteriol 1993 Jun;175(11):3343-52
neutrophil cytosol factor 67K  0   *Phosphoproteins NADH Dehydrogenase NADPH Dehydrogenase Neutrophils NADPH Oxidase. Biochem J 1993 Feb 15;290(Pt 1):173-8
ndhB protein, Arabidopsis  EC 1.6.5.3   *NADH Dehydrogenase *Arabidopsis Proteins. Nucleic Acids Res 1992 Dec 11;20(23):6189-94
4-chlorophenylmethoxybenzyl ketoxime  138772-64-2   *Oximes NADH Dehydrogenase/antagonists & inhibitors. FEBS Lett 1991;287(1-2):215
Tinopal AN  24260-77-3   *Benzoxazoles NADH Dehydrogenase/antagonists & inhibitors. FEBS Lett 1982;104(2):248

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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