encyclopedia of medical concepts
ψ 

Naphthyridines

More information in Books or onNLM PubMed
Definition:      
Examples Nalidixic Acid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-(4-fluoro-2-methoxy-benzyl)-7-hydroxy-8,9-dihydro-3H,7H-pyrrolo(2,3-c)(1,7)naphthyridin-6-one  0   *Naphthyridines HIV Integrase Inhibitors. Xenobiotica. 2012 Jan;42(1):57-74.
NM13 compound  0   *Naphthyridines Anti-HIV Agents. ChemMedChem. 2011 Jul 4;6(7):1249-57
3-(4-(3-chlorophenyl)-1-ethyl-7-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)propanoic acid  0   *Naphthyridines Cyclic Nucleotide Phosphodiesterases, Type 4. Int Immunopharmacol 2011 Jun;11(6):732-9
Genz-644282  0   *Naphthyridines. Clin Cancer Res. 2011 May 1;17(9):2777-87
PF 00217830  0   *Naphthyridines *Piperazines. Bioorg Med Chem Lett 2011 May 1;21(9):2621-5
9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo(h)(1,6)naphthyridin-2(1H)-one  0   *Naphthyridines. J Med Chem 2011 Mar 10;54(5):1473-80
CX 5461  0   *Naphthyridines *Benzothiazoles RNA Polymerase I/antagonists & inhibitors. Cancer Res 2011 Feb 15;71(4):1418-30
1-hydroxy-1,8-naphthyridin-2(1H)-one  0   *Naphthyridines. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6754-7
7-(2-methoxyethoxy)-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine  0   *Naphthyridines *Pyridazines. Chem Res Toxicol 2010 Nov 15;23(11):1743-52
7-methoxy-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine  0   *Naphthyridines *Pyridazines Carbon Radioisotopes. Chem Res Toxicol 2010 Nov 15;23(11):1743-52
5-(3-chlorophenylamino)benzo(c)(2,6)naphthyridine-8-carboxylic acid  0   *Naphthyridines Casein Kinase II/antagonists & inhibitors. Cancer Res 2010 Dec 15;70(24):10288-98
1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one  0   *Naphthyridines. J Med Chem 2010 Oct 14;53(19):7146-55
1,8-naphthyridine-pyrido(2,3-b)pyrazine  0   *Naphthyridines *Pyrazines. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4359-63
GSK966587  0   *Naphthyridines. Org Lett. 2010 Aug 6;12(15):3422-5
4-(2-(4-methoxybenzyl)perhydropyrido(3,2,1-ij)(1,6)naphthyridin-1-yl)butanoic acid  0   *Naphthyridines. Hepatology 2010 Sep;52(3):845-53
2,4,9-trimethylbenzo(b)(1,8)naphthyridin-5-amine  0   *Naphthyridines. J Pharmacol Exp Ther 2010 Sep 1;334(3):988-98
cyclohexyl-(4-(1-piperazin-1-yl(2,6)naphthyridin-3-yl)pyridin-2-yl)amine  0   *Aminopyridines *Naphthyridines. J Med Chem 2010 Aug 12;53(15):5400-21
vinyl-1,8-naphthyridine  0   *Naphthyridines *Vinyl Compounds. Inorg Chem. 2010 May 17;49(10):4524-33
ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo(b)(1,8)naphthyridine-3-carboxylate  0   *Naphthyridines Acetylcholinesterase. Bioorg Med Chem Lett 2010 May 1;20(9):2950-3
1-cyclopropyl-5-fluoro-7-(4-(4-formyl-1H-1,2,3-triazol-1-yl)piperidin-1-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid  0   *Naphthyridines. Bioorg Med Chem Lett 2010 May 1;20(9):2859-63
7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo(3,4-c)(2,7)-naphthyridin-1-ylamine  0   *Naphthyridines *Pyrazoles Receptors, Bombesin/agonists. Bioorg Med Chem Lett 2010 May 1;20(9):2785-9
((3)H)-1-methyl-5-((N-propylpiperidin-4-yl)methoxy)pyrrolo(1,2-a)thieno(2,3-e)pyrazinenzo(h)(1,6)naphthyridine  0   *Naphthyridines. Eur J Med Chem. 2010 Mar;45(3):1263-5
((3)H)-5-((N-propylpiperidin-4-yl)methoxy)-1,2,3,4-tetrahydrobenzo(h)(1,6) naphthyridine  0   *Naphthyridines *Piperidines. Eur J Med Chem. 2010 Mar;45(3):1263-5
7-(3-(trifluoromethyl)pyridin-2-yl)-N-(5-(trifluoromethyl)pyridin-2-yl)-1,8-naphthyridin-4-amine  0   *Naphthyridines TRPV Cation Channels/antagonists & inhibitors. J Med Chem 2010 Apr 22;53(8):3330-48
N-(3-(1-methylethyl)-3-((3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)carbonyl)cyclopentyl)tetrahydro-2H-pyran-4-amine  0   *Naphthyridines Receptors, CCR2/antagonists & inhibitors. Arterioscler Thromb Vasc Biol 2010 Feb;30(2):253-9
4-(3-(2-nitro-1-imidazolyl)propylamino)-1,5-naphthyridine hydrochloride  0   *Naphthyridines *Nitroimidazoles. Anticancer Drugs. 2009 Jul;20(6):493-502
pyrimido(4,5-b)(1,6)naphthyridine  0   *Naphthyridines. J Comb Chem. 2009 Sep-Oct;11(5):809-12
4,5,7a,8,9,10,11,11a-octohydro-7H-10-methylindolol(1,7bc)(2,6)-napthyridine  0   *Indoles *Naphthyridines. Neuropharmacology. 2009 Sep;57(3):259-67
7-chloro-4-hydroxy-2-phenyl-1,8-naphthyridine  0   *Naphthyridines Receptor, Adenosine A1/antagonists & inhibitors. Blood 2009 Jul 30;114(5):1110-22
N-(3-aminopropyl)-5,6,7-trimethyl-1,8-naphthyridine-2-amine  0   *Naphthyridines. Nucleic Acids Symp Ser (Oxf) 2008;(52):117-8
3-(isopentylamino)demethyl(oxy)aaptamine  0   *Naphthyridines. Mar Drugs 2009;7(1):1-8
3-(phenethylamino)demethyl(oxy)aaptamine  0   *Naphthyridines. Mar Drugs 2009;7(1):1-8
4-methoxy-5-hydroxycanthin-6-one  0   *Indoles *Naphthyridines. Planta Med 2009 Feb;75(2):142-5
(6-(3-chloro-4-fluoro-benzyl)-4-hydroxy-2-methyl-3,5-dioxo-2,3,5,6,7,8-hexahydro-(2,6)naphthyridine-1-carboxylic acid dimethylamide)  0   *Dimethylamines *Naphthyridines. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 1;875(1):118-21
2,7-diamino-1,8-naphthyridine  0   *Naphthyridines. Bioorg Med Chem. 2008 Dec 15;16(24):10338-44
N,N-bis((benzo(g)(1,5)naphthyridin-2-yl)methyl)propane-2-amine  0   *Naphthyridines Ligands. Angew Chem Int Ed Engl. 2008;47(50):9768-71
N-(2-(dimethylamino)ethyl)-2,6-dimethyl-1-oxo-1,2-dihydroxybenzo(b)-1,6-naphthyridine-4-carboxamide  0   *Naphthyridines. Cancer Chemother Pharmacol 2008 Oct;62(5):753-62
1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-naphthyl ester  0   *Naphthalenes *Naphthyridines.
N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamide  0   *Naphthyridines. Bioorg Med Chem Lett 2008 Oct 1;18(19):5309-10
MK 0873  0   *Naphthyridines Cyclic Nucleotide Phosphodiesterases, Type 4/antagonists & inhibitors. Pulm Pharmacol Ther 2008;21(3):573-7
12-aza-5H-8,9-dimethoxy-5-(2-(N,N-dimethylamino)ethyl)-2,3-methylenedioxydibenzo(c,h)(1,6)naphthyridin-6-one  0   *Naphthyridines. Bioorg Med Chem Lett 2008 Jun 15;18(12):3570-2
pumafentrine  0   *Naphthyridines. Eur Respir J 2008 Mar;31(3):599-610
2-amino-5,6,7-trimethyl-1,8-naphthyridine  0   *Naphthyridines. Nucleic Acids Symp Ser (Oxf) 2007;(51):313-4
4-(3-(7-methyl-1,8-naphthyridin-2-ylamino)propyl)-7-N,N-dimethylaminosulfonylbenzo-2-oxa-1,3-diazole  0   *Naphthyridines *Oxadiazoles Ligands. Nucleic Acids Symp Ser (Oxf) 2007;(51):297-8
N-(5,7-dimethyl-1,8-naphthyridin-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid-10-acetamide  0   *Heterocyclic Compounds, 1-Ring *Naphthyridines. Nucleic Acids Symp Ser (Oxf) 2007;(51):303-4
2-(ferrocenylmethylamino)-7-methyl-1,8-naphthyridine  0   *Ferrous Compounds *Naphthyridines. Nucleic Acids Symp Ser (Oxf) 2007;(51):295-6
2-ethyl-8-(4-fluorophenyl)-6-methyl-3,4-dihydro-2H-(2,7)naphthyridin-1-one  0   *Naphthyridines. Biochem Pharmacol 2008 Mar 1;75(5):1054-64
ferrocenyl aminonaphthyridine  0   *Ferrous Compounds *Naphthyridines. Org Biomol Chem. 2008 Jan 21;6(2):266-8
JNJ-26076713  0   *Naphthyridines *Quinolines. J Pharmacol Exp Ther 2008 Mar;324(3):894-901
2,6-diauro-1,5-naphthyridine  0   *Naphthyridines. Phys Chem Chem Phys. 2008 Jan 7;10(1):114-20
GPD-1116  0   *Naphthyridines. Am J Physiol Lung Cell Mol Physiol 2008 Feb;294(2):L196-204
2-(4-methyl piperazin-1-yl)-1,8-naphthyridine-3-carbonitrile  0   *Naphthyridines *Nitriles. Pharmazie. 2007 Dec;62(12):919-24
1-tert-butyl-1,4-dihydro-7-(4,4-dimethyloxazolidin-3-yl)-6-nitro-4-oxo-1,8-naphthyridine-3-carboxylic acid  0   *Naphthyridines. J Med Chem 2007 Nov 29;50(24):6232-9
bioxalomycin beta2  0   *Naphthyridines *Oxazoles. inhibits 5-enolpyruvylshikimate-3-phosphate synthase; structure in first source15460-1
5,10-dihydrobenzo(beta)(1,8)naphthyridine-N-oxide  0   *Cyclic N-Oxides *Naphthyridines. Chem Res Toxicol. 2007 Nov;20(11):1709-17
canthin-6-one-1-O-xylopyranosyl-1-6-glucopyranoside  0   *Disaccharides *Naphthyridines. J Asian Nat Prod Res 2007 Apr-Aug;9(3-5):253-9
canthin-6-one-5-O-xylopyranosyl-1-6-glucopyranoside  0   *Disaccharides *Naphthyridines. J Asian Nat Prod Res 2007 Apr-Aug;9(3-5):253-9
8,9-demethylaaptamine  0   *Naphthyridines. Mar Biotechnol (NY) 2006 Jul-Aug;8(4):366-72
N,N'-bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine  0   *Naphthyridines. Chemistry 2007;13(16):4452-7
7-(4-aza-6-(7-methylnaphthyridin-2-ylcarbonyl)hexanamidomethyl)-8-azaquinolone  0   *Naphthyridines *Quinolones Ligands. Nucleic Acids Symp Ser (Oxf) 2006;(50):147-8
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy