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Neoplasm Proteins

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Definition: Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (TUMOR MARKERS, BIOLOGICAL) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.  IM & coord with specific protein (IM) + specific histol type (IM) + specific organ/neoplasms term (IM); Manual 24.4.4.4   
See Also Antigens, Neoplasm; Tumor Markers, Biological
Examples Melanoma-Specific Antigens; Myeloma Proteins; Oncogene Proteins; Tumor Suppressor Proteins 		Other names Proteins, Neoplasm
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TMEM207 protein, human  0   *Carrier Proteins *Membrane Proteins Neoplasm Proteins. Carcinogenesis. 2012 Mar;33(3):548-54.
Bcas1 protein, mouse  0   *Neoplasm Proteins. Neurosci Res. 2011 Jul;70(3):269-76
ERRF protein, human  0   *Nuclear Proteins Neoplasm Proteins. Am J Pathol. 2012 Mar;180(3):1189-201.
C4.4A protein, rat  0   *Neoplasm Proteins *GPI-Linked Proteins. Oncogene. 1998 Oct 15;17(15):1989-2002.
CREPT protein, human  0   *Neoplasm Proteins *Cell Cycle Proteins. Cancer Cell. 2012 Jan 17;21(1):92-104
CREPT protein, mouse  0   *Neoplasm Proteins *Cell Cycle Proteins. Cancer Cell. 2012 Jan 17;21(1):92-104
SLC35F2 protein, human  0   *Membrane Transport Proteins Neoplasm Proteins. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11032-7.
novel metastasis-promoting gene 1 protein, human  0   *Neoplasm Proteins. J Pathol 2011 Sep;225(1):96-105
OS9 protein, mouse  0   *Neoplasm Proteins *Lectins. Mol Med Report. 2011 Jul-Aug;4(4):687-92
PRUNE2 protein, mouse  0   *Neoplasm Proteins. J Mol Neurosci. 2011 Jun;44(2):103-14
POTE ankyrin domain family, member H, human  0   *Proteins Antigens, Neoplasm Neoplasm Proteins Ankyrin Repeat. Brain Res 2011 May 19;1391:125-31
Pramel6 protein, mouse  0   *Antigens, Neoplasm *Neoplasm Proteins. Stem Cells 2011 Mar;29(3):474-85
Pramel7 protein, mouse  0   *Antigens, Neoplasm *Neoplasm Proteins. Stem Cells 2011 Mar;29(3):474-85
IRIZIO protein, human  0   *Neoplasm Proteins. Carcinogenesis 2011 Apr;32(4):452-61
PLXDC2 protein, human  0   *Receptors, Cell Surface Neoplasm Proteins Tumor Markers, Biological. Ophthalmology. 2011 Apr;118(4):642-8
Biot2 protein, human  0   *Neoplasm Proteins Tumor Markers, Biological. Oncol Rep 2011 Jan;25(1):75-80
PHF10 protein, human  0   *Neoplasm Proteins *Homeodomain Proteins Zinc Fingers. Mol Cancer Ther 2010 Jun;9(6):1764-74
DOC45 protein, human  EC 3.6.1.-   *Adenosine Triphosphatases Neoplasm Proteins. Mol Cancer Res 2010 Jan;8(1):57-66
CD109 protein, mouse  0   *Neoplasm Proteins *Antigens, CD. J Dermatol Sci. 2010 Feb;57(2):140-2
TM9SF4 protein, human  0   *Membrane Proteins Neoplasm Proteins Biological Markers. EMBO Rep 2009 Dec;10(12):1348-54
MELOE-2 antigen, human  0   *Antigens, Neoplasm *Neoplasm Proteins. Cancer Immunol Immunother 2010 Mar;59(3):431-9
T351 protein, human  0   *Membrane Proteins *Neoplasm Proteins. Cancer Biol Ther 2009 May;8(9):835-43
J1-31 protein, human  0   *Nerve Tissue Proteins Neoplasm Proteins. Neuropathology. 2009 Oct;29(5):521-7
REG4 protein, mouse  0   *Neoplasm Proteins. PLoS One 2009;4(10):e7495
FAM46D protein, human  0   *Neoplasm Proteins. Genomics 2009 Sep;94(3):153-60
RHBDD2 protein, human  0   *Neoplasm Proteins. Biochim Biophys Acta 2009 Oct;1792(10):988-97
esophageal cancer related gene 4 protein, mouse  0   *Neoplasm Proteins. Gene. 2009 Dec 1;448(1):7-15
GPATCH2 protein, human  0   *Carrier Proteins *Neoplasm Proteins. Cancer Sci 2009 Aug;100(8):1443-50
RTAP2 protein, rat  0   *Neoplasm Proteins. J Biosci Bioeng 2009 Jun;107(6):589-95
STEAP1 protein, rat  0   *Antigens, Surface *Neoplasm Proteins. Endocrine 2008 Aug-Dec;34(1-3):108-16
LRRC26 protein, human  0   *Neoplasm Proteins. Biochem Biophys Res Commun 2009 Mar 13;380(3):508-13
ZKSCAN3 protein, mouse  0   *Transcription Factors Neoplasm Proteins Zinc Fingers. J Biol Chem 2008 Dec 12;283(50):35295-304
C8orf4 protein, mouse  0   *Neoplasm Proteins. BMB Rep 2008 Oct 31;41(10):733-8
NGO-Pr-54 protein, human  0   *Neoplasm Proteins. Cancer Immun. 2008;8() (dup#9):15
MELOE-1 antigen, human  0   *Antigens, Neoplasm *Neoplasm Proteins. J Exp Med 2008 Oct 27;205(11):2673-82
Hec1 protein, mouse  0   *Microtubule-Associated Proteins *Cell Cycle Proteins Neoplasm Proteins Nuclear Proteins. Proc Natl Acad Sci U S A 2008 Oct 28;105(43):16719-24
GP-1D8 glycoprotein, human  0   *Glycoproteins Neoplasm Proteins. Prep Biochem Biotechnol. 2008;38(4):321-33
ugene protein, human  0   *Carrier Proteins *Neoplasm Proteins Nuclear Proteins. Cancer Res 2008 Aug 1;68(15):6118-26
EMSY protein, mouse  0   *Neoplasm Proteins *Nuclear Proteins *Repressor Proteins. J Biosci 2008 Mar;33(1):27-44
BJ-TSA-9 protein, human  0   *Neoplasm Proteins Tumor Markers, Biological. Biochem Biophys Res Commun 2008 Aug 8;372(4):756-60
Blcap protein, mouse  0   *Membrane Proteins *Neoplasm Proteins. RNA 2008 Jun;14(6):1110-8
P16 protein, human  0   *Neoplasm Proteins. Gynecol Oncol. 2008 May;109(2):285-90
ovarian cancer immuno-reactive antigen domain containing 1, human  0   *Neoplasm Proteins. Gynecol Oncol. 2008 May;109(2):226-33
Dnd1 protein, human  0   *Neoplasm Proteins. Genes Chromosomes Cancer. 2008 Mar;47(3):247-52
GSDMB protein, human  0   *Neoplasm Proteins. Pathology 2008 Jan;40(1):13-24
TAX1BP1 protein, mouse  0   *Neoplasm Proteins *Intracellular Signaling Peptides and Proteins Apoptosis. EMBO J 2007 Sep 5;26(17):3910-22
HEPT3 protein, human  0   *Neoplasm Proteins. Int J Oncol 2007 Aug;31(2):293-301
Melan-A 51-73 peptide  0   *Antigens, Neoplasm *Neoplasm Proteins Peptide Fragments. Cancer Immunol Immunother. 2007 Oct;56(10):1565-75
peptide NY-ESO-1 157-170  0   *Neoplasm Proteins *Peptide Fragments. Proc Natl Acad Sci U S A 2007 Jul 31;104(31):12837-42
FAM134B protein, human  0   *Neoplasm Proteins. Int J Mol Med 2007 Jun;19(6):915-23
NBPF3 protein, human  0   *Neoplasm Proteins. Virology 2007 May 25;362(1):1-5
MAGEA9 protein, human  0   *Antigens, Neoplasm *Neoplasm Proteins. Clin Cancer Res 2007 Mar 15;13(6):1713-9
PC3-secreted microprotein, human  0   *Neoplasm Proteins. Biol Chem 2007 Mar;388(3):289-95
MIEN1 protein, human  0   *Neoplasm Proteins *Intracellular Signaling Peptides and Proteins Tumor Markers, Biological. Mol Cancer Ther 2006 Nov;5(11):2919-30
Ikaros 6 protein, rat  0   *Ikaros Transcription Factor Neoplasm Proteins. Mol Endocrinol 2006 Nov;20(11):2976-86
FAM163A protein, human  0   *Membrane Proteins *Neoplasm Proteins Tumor Markers, Biological. J Pediatr Surg 2007 Jan;42(1):148-52
C8orf17 protein, human  0   *Neoplasm Proteins. Int J Oncol. 2007 Jan;30(1):81-9
NACC1 protein, human  0   *Neoplasm Proteins *Repressor Proteins Zinc Fingers. Proc Natl Acad Sci U S A 2006 Dec 5;103(49):18739-44
Tax1-binding protein 1, rat  0   *Intracellular Signaling Peptides and Proteins Neoplasm Proteins Apoptosis. Biochem J 2007 Jan 15;401(2):429-36
FAM129A protein, human  0   *Neoplasm Proteins *Tumor Markers, Biological. Hum Pathol 2006 Dec;37(12):1592-600
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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