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Multiple Endocrine Neoplasia

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Definition: A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively.  general or unspecified; prefer specifics; coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent; DF MULTIPLE ENDOCRINE NEOPL   
Examples Multiple Endocrine Neoplasia Type 1; Multiple Endocrine Neoplasia Type 2a; Multiple Endocrine Neoplasia Type 2b 		Other names Neoplasms, Multiple Endocrine; Neoplasia, Multiple Endocrine; Endocrine Neoplasia, Multiple; Adenomatosis, Familial Endocrine; Multiple Endocrine Adenopathies; Multiple Endocrine Adenomatosis; Multiple Endocrine Adenomatoses; Familial Endocrine Adenomatosis; Familial Endocrine Adenomatoses; Endocrine Neoplasms, Multiple; Endocrine Adenopathy, Multiple; Endocrine Adenopathies, Multiple; Endocrine Adenomatosis, Multiple; Endocrine Adenomatosis, Familial; Endocrine Adenomatoses, Multiple; Endocrine Adenomatoses, Familial; Adenopathy, Multiple Endocrine; Adenopathies, Multiple Endocrine; Adenomatoses, Multiple Endocrine; Adenomatoses, Familial Endocrine

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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