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S100 Proteins

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Definition: A family of highly acidic calcium-binding proteins found in large concentration in the brain and believed to be glial in origin. They are also found in other organs in the body. They have in common the EF-hand motif (EF HAND MOTIFS) found on a number of calcium binding proteins. The name of this family derives from the property of being soluble in a 100% saturated ammonium sulfate solution.     
Examples Leukocyte L1 Antigen Complex 		Other names Nerve Tissue Protein S 100; Antigen S 100; S 100 Protein; S100 Protein Family; S-100 Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
S100A16 protein, rat  0   *S100 Proteins. Biochem Biophys Res Commun. 2004 Jan 9;313(2):237-44.
trichohyalin-like 1 protein, human  0   *S100 Proteins. J Invest Dermatol. 2011 Aug;131(8):1761-3
S100A16 protein, mouse  0   *S100 Proteins. Endocrinology 2011 Mar;152(3):903-11
S100A2 protein, mouse  0   *S100 Proteins. Arch Dermatol Res 2009 Mar;301(3):205-17
sentan protein, mouse  0   *Microtubule-Associated Proteins S100 Proteins. Mol Biol Cell 2008 Dec;19(12):5338-46
CBRLK1 protein, Arabidopsis  EC 2.7.11.1   *Protein-Serine-Threonine Kinases *Arabidopsis Proteins S100 Proteins. FEBS Lett 2009 Jan 5;583(1):36-42
S100A11 protein, mouse  0   *S100 Proteins. J Immunol 2008 Jun 15;180(12):8378-85
dicalcin protein, Xenopus  0   *S100 Proteins *Xenopus Proteins Egg Proteins. DNA Seq 2007 Oct;18(5):400-4
S-100A8 N-terminal peptide, human  0   *S100 Proteins Peptide Fragments. Clin Chim Acta 2006 Oct;372(1-2):120-8
S100A15 protein, mouse  0   *S100 Proteins. J Invest Dermatol 2006 Jul;126(7):1600-8
S100a13 protein, mouse  0   *S100 Proteins.
S100A13 protein, human  0   *S100 Proteins.
S100A7A protein, human  0   *S100 Proteins. FASEB J 2003 Oct;17(13):1969-71
S100RVP protein, rat  0   *S100 Proteins. Prostate 2006 May 15;66(7):768-78
S100A7 protein, mouse  0   *S100 Proteins Tumor Markers, Biological. BMC Cancer 2005 Feb 17;5(1):17
S100A4 protein, Bos taurus  0   *S100 Proteins.
S100a4 protein, rat  0   *S100 Proteins.
S100a3 protein, mouse  0   *S100 Proteins Hair Follicle.
S100a6 protein, mouse  0   *S100 Proteins *Cell Cycle Proteins.
calcyclin protein, Gallus gallus  0   *S100 Proteins *Cell Cycle Proteins.
S100a6 protein, rat  0   *S100 Proteins *Cell Cycle Proteins.
S100A2 protein, rat  0   *Chemotactic Factors *S100 Proteins. Cell Mol Biol (Noisy-le-grand) 2003 Jun;49(4):485-6
S100a4 protein, mouse  0   *S100 Proteins. J Biomol NMR 2002 Jun;23(2):153-4
S100Z protein, human  0   *S100 Proteins EF Hand Motifs. Biochemistry 2001 Dec 25;40(51):15538-48
calcitermin peptide, human  0   *S100 Proteins *Peptides. FEBS Lett. 2001 Aug 24;504(1-2):5-10
S100 calcium binding protein A10  0   *S100 Proteins *Annexin A2 Apoptosis. J Biol Chem 1987 Aug 5;262(22):10663-71
P26OLF protein, Rana catesbeiana  0   *S100 Proteins *Amphibian Proteins Ranidae. Biochem Biophys Res Commun 1998 Oct 29;251(3):860-7
calcium-binding protein p6, human  0   *S100 Proteins. Protein Expr Purif 1998 Aug;13(3):313-8
S100A1 protein  0   *S100 Proteins. Biochemistry 1996 May 21;35(20):6263-6
RPTN protein, mouse  0   *S100 Proteins. Genomics 1997 Aug 1;43(3):339-48
S100A2 protein, human  0   *Chemotactic Factors *S100 Proteins. J Cell Biol 1989 Feb;108(2):569-78
S100A12 protein, human  0   *S100 Proteins. Biochem Biophys Res Commun 1996 Aug 5;225(1):146-50; J Biol Chem 1994 Nov 18;269(46):28929-36
S100A7 protein, human  0   *S100 Proteins Tumor Markers, Biological. J Invest Dermatol 1994 Sep;103(3):370-5
S100A3 protein, human  0   *S100 Proteins. J Invest Dermatol 1998 Nov;111(5):879-86; Proc Natl Acad Sci U S A 1993 Jul 15;90(14):6547-51
S100A5 protein, human  0   *S100 Proteins. Proc Natl Acad Sci U S A 1993 Jul 15;90(14):6547-51
S100A4 protein, human  142662-27-9   *S100 Proteins. Biochemistry 1992 Oct 27;31(42):10258-64; Oncogene 1992 Jan;7(1):109-19
S100A11 protein, human  146909-89-9   *S100 Proteins. FEBS Lett 1991;295(1-3):93
S-100 calcium-binding protein beta subunit  0   *Nerve Growth Factors *S100 Proteins Autoantigens Biological Markers. Proc Natl Acad Sci USA 1991;88(9):3554
S100A6 protein, human  105504-00-5   *S100 Proteins *Cell Cycle Proteins. J Biol Chem 1988;263(10):4758
S-100 calcium-binding protein alpha subunit  0   *S100 Proteins. Eur J Biochem 1981;115(3):469

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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