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Nigericin

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Definition: A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)     
Pharmacological Action Ionophores; Anti-Bacterial Agents 		Other names Pandavir; Epinigericin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
octacyclomycin  98824-17-0   Nigericin/*analogs & derivatives Streptomyces. J Antibiot (Tokyo) 1992 Oct;45(10):1686-91
1,30-didehydroxy-1,30-dichloronigericinol  138285-65-1   Nigericin/*analogs & derivatives. J Med Chem 1992 Mar 6;35(5):939-44
semduramicin  113378-31-7   Nigericin/*analogs & derivatives Ionophores. Anal Chem 1991 Sep 1;63(17):1789-94
2-epimutalomycin  124985-96-2   Nigericin/*analogs & derivatives. J Antibiot (Tokyo) 1989;42(6):897
28-epimutalomycin  124918-42-9   Nigericin/*analogs & derivatives. J Antibiot (Tokyo) 1989;42(6):897
lonomycin C  68537-50-8 Lonomycin A, 2-demethyl  Nigericin/*analogs & derivatives. J Antibiot (Tokyo) 1980:33(11):1224
A-130C  73522-76-6 Dianemycin, 10-demethyl-19-de((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-, (11(2R,5S,6R),12R,28S)  Nigericin/*analogs & derivatives. J Antibiot (Tokyo) 1980;33(1):94
A-130B  73492-07-6 Dianemycin, 10-demethyl-19-de((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-27-((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-, (11(2R,5S,6R),12R,27S(2R,5S,6R))  Nigericin/*analogs & derivatives. J Antibiot (Tokyo) 1980;33(1):94
dihydrogrisorixin  71641-04-8 Nigericin, 25,29-deepoxy-30-deoxy-25-hydroxy  Nigericin/*analogs & derivatives Ionophores. J Antibiot (Tokyo) 1979;32(7):740
mutalomycin  62618-08-0 Lonomycin A, 23,27-didemethoxy-11-O-demethyl  Nigericin/*analogs & derivatives. J Antibiot (Tokyo) 1979;31(5):535; J Antibiot 30(11):903;1977
lonomycin  58785-63-0   Nigericin/*analogs & derivatives Ionophores. Experientia 32(3):318;1976; J Antibiot 29(1):14-15;1976; J Antibiot 29(4):354;1976; J Antibiot 31(9):929;1978; Poult Sci 57(5):1227;1978
grisorixin  31357-58-1   Nigericin/*analogs & derivatives Ionophores. Biochim Biophys Acta 511(3):499;1978; Biochimie 57(6-7):787;1975; Biochimie 59:497;1977; J Antibiot (Tokyo) 1979;32(7):740; J Antibiotics 28(5):345;1975; J Antibiotics 28(5):351;1975

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