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Nitromifene

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Definition: A non-steroidal estrogen antagonist (as the 1:1 citrate) most commonly used as a research tool in animal studies.     
Pharmacological Action Estrogen Antagonists 		Other names CI 628; Nitromiphene; Nitromifene, (Z)-Isomer; Nitromifene, (E)-Isomer; Nitromifene Citrate (1:1); Nitromifene Citrate; CN-55945-27; CN-55,945-27; CI628; CI-628
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(4-(2-nitro-1-(4-methoxyphenyl)-2-phenylvinyl)phenoxy)-N-ethylpyrrolidin-2-one  87261-96-9   Nitromifene/*analogs & derivatives. J Med Chem 1983;26(12):1701
2-(4-methoxyphenyl)-4'-(2-(1-pyrrolidinyl)ethoxy)deoxybenzoin  87198-64-9   Nitromifene/*analogs & derivatives Receptors, Estrogen/drug effects. J Med Chem 1983;26(12):1701; Life Sci 1983;33(11):1051
4-(beta(N-pyrrolidinyl)ethoxy)-4'-methoxybenzophenone  13278-77-8 Methanone, (4-methoxyphenyl)(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)  Nitromifene/*analogs & derivatives. Life Sci 1983;33(11):1051

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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