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Norpregnadienes

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Definition: Pregnadienes which have undergone ring contractions or are lacking carbon-18 or carbon-19.     
Examples Promegestone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
17,20-((1-methoxyethylidene)bis(oxy))-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester  0   *Norpregnadienes Androgens. Biol Pharm Bull 2011 Mar;34(3):318-23
ulipristal acetate  0   *Norpregnadienes Contraceptive Agents. Obstet Gynecol 2010 Feb;115(2 Pt 1):257-63ELLA
CDB 4124  0   *Norpregnadienes. Mol Cell Endocrinol 2002 Feb 25;188(1-2):111-23
CDB-4453  0   *Norpregnadienes. Mol Cell Endocrinol 2002 Feb 25;188(1-2):111-23
quingestanol  10592-65-1   *Norpregnadienes. Chung Hua Fu Chan Ko Tsa Chih 1979;14(2):68
ulipristal  0   *Norpregnadienes. Contraception 1995 Mar;51(3):215-8
buxaminol E  14155-76-1 B(9a)-Homo-19-norpregna-9(11),9a-dien-16-ol, 20-amino-3-(dimethylamino)-4,4,14-trimethyl-, (3beta,5alpha,16alpha,20S)  *Alkaloids *Norpregnadienes. Bratisl Lek Listy 1990;91(4):309
RU 25055  67983-56-6   *Norpregnadienes. Cancer Lett 1985;27(3):329
nomegestrol acetate  58652-20-3   *Megestrol *Norpregnadienes Antineoplastic Agents, Hormonal Progesterone Congeners. Arzneimittelforsch 1983;33(5):710
Me-quingestanol  79030-51-6   *Norpregnadienes *Megestrol Acetate Contraceptives, Oral, Combined. Chung Hua Fu Chan Ko Tsa Chih 1979;14(2):68
ethynerone  3124-93-4 21-chloro-17-hydroxy-19-nor-17 alpha-pregna-4,9-dien- 20-yn-3-one  *Norpregnadienes Progesterone Congeners. Exp Mol Pathol 30(2):279;1979; J Nat Can Inst 60(6):1351;1978
(4R)-5,10-seco-19-norpregna-4,5-diene-3,10,20-trione  60398-19-8 1H-Cyclodec(e)indene-6,9-dione, 3-acetyl-11,12-didehydro-2,3,3a,4,5,5a,7,8,12,13,13a,13b-dodecahydro-3a-methyl-, (3S-(3R*,3aR*,5aR*,10S*,13aR*,13bR*))  *Norpregnadienes. J Steroid Biochem 8(4):307;1977
norgesterone  13563-60-5 17-beta-hydroxy-19-nor-17-alpha-pregna-5(10),20- dien-3-one  *Norpregnadienes Progesterone Congeners.
amadinone  30781-27-2 6-chloro-17-acetoxy-19-norpregnane-4,6-diene-3,20-dione  *Norpregnadienes. Clin Pharmacol Therap 13(2):205;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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