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Noscapine

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Definition: A naturally occurring opium alkaloid that is a centrally acting antitussive agent.     
Pharmacological Action Antitussive Agents 		Other names Narcotine; prikkelhoest, Librochin; Tropfen, Capval; Noscapine Dreluso Brand; Hydrogen Embonate, Noscapine; Hydrochloride, Noscapine; Embonate, Noscapine Hydrogen; Tuscalman; Noscapine Hydrogen Embonate; Noscapine Hydrochloride; Noscapect; Librochin prikkelhoest; Dreluso Brand of Noscapine Hydrochloride; Dreluso Brand of Noscapine; Capval Tropfen; Capval; Byk Brand of Noscapine Hydrochloride; Boots Brand of Noscapine Hydrochloride; Berna Brand of Noscapine Hydrochloride
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
9-azido-noscapine  0   Noscapine/*analogs & derivatives Antineoplastic Agents. J Biomol Screen. 2011 Oct;16(9):1047-58
amino-noscapine  0   Noscapine/*analogs & derivatives. J Comput Aided Mol Des. 2011 May;25(5):443-54
9-bromo-5-(4,5-dimethoxy-1,3-dihydroisobenzofuran-1-yl)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-(1,3)-dioxolo(4,5-g)isoquinoline  0   Noscapine/*analogs & derivatives. J Biol Chem 2010 Jun 11;285(24):18737-48
meconin  0   Noscapine/*analogs & derivatives Biological Markers/urine. Anal Toxicol 2007 Mar;31(2):105-8
9-nitronoscapine  0   Noscapine/*analogs & derivatives. Mol Pharmacol 2006 Jun;69(6):1801-9
EM015  0   Noscapine/*analogs & derivatives. Cancer Res 2006 Apr 1;66(7):3782-91
N-methylnoscapine  0   Noscapine/*analogs & derivatives. J Med Chem 2005 Jul 28;48(15):4972-82
narcotoline  521-40-4   Noscapine/*analogs & derivatives. J Chromatogr 1988;459:301
alpha-narcotinediol  23942-99-6   Noscapine/*analogs & derivatives. Pharmazie 1988;43(8):561
spasmofen  82824-08-6 Morphinan 3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5alpha,6alpha)-, hydrochloride, mixt. with (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol hydrochloride, 1-((3,4-dimethoxyphenyl)methyl)-6,7-dimethoxyisoquinoline hydrochl  *Codeine *Morphine *Noscapine *Papaverine *Scopolamine Derivatives Drug Combinations. Lancet 1982;1(8281):1096
Neo-fluvaleas  79682-27-2 Benzenepropanaminium, gamma-(aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-gamma-phenyl-, iodide, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, (S-(R*,S*))-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinoli  *Acetaminophen *Quaternary Ammonium Compounds *Diphenhydramine *Noscapine Drug Combinations. Arch Sci Med (Torino) 1980;137(2):321
Fluvaleas  79682-26-1 Benzenepropanaminium, gamma-(aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-gamma-phenyl-, iodide, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, (S-(R*,S*))-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinoli  *Acetaminophen *Quaternary Ammonium Compounds *Amobarbital *Noscapine Drug Combinations. Arch Sci Med (Torino) 1980;137(2):321
l-alpha-methyl-8-methoxy-6,7-dihydroxy-1-(6,7-dimethoxy-3-phthalidyl)-1,2,3,4-tetrahydroisoquinoline  78213-27-1 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(1,2,3,4-tetrahydro-6,7-dihydroxy-8-methoxy-2-methyl-1-isoquinolinyl)-, (S-(R*,S*))  *Tetrahydroisoquinolines Noscapine/*analogs & derivatives. Xenobiotica 1981;11(1):23
narcotic acid  55836-07-2   Noscapine/*analogs & derivatives. Pol J Pharmacol Pharm 27(1):69;1975
duopect  76404-10-9 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, hydrochloride, (S-(R*,S*))-, mixt. with 1-(4-hydroxy-3-methoxyphenyl)-1,2,3-propanetriol  *Noscapine *Guaifenesin Drug Combinations. Arch Immunol Therap Exp 23(1):135;1975

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