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Nucleoside Q

More information in Books or onNLM PubMed
Definition: A modified nucleoside which is present in the first position of the anticodon of tRNA-tyrosine, tRNA-histidine, tRNA-asparagine and tRNA-aspartic acid of many organisms. It is believed to play a role in the regulatory function of tRNA. Nucleoside Q can be further modified to nucleoside Q*, which has a mannose or galactose moiety linked to position 4 of its cyclopentenediol moiety.  /biosyn /physiol permitted    Other names Q Ribonucleoside; Q-Ribonucleoside; Q Nucleoside; Nucleoside Q*; Queuosine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7-aminomethyl-7-deaza-2'-deoxyguanosine  0   Nucleoside Q/*analogs & derivatives. J Am Chem Soc 2009 Sep 2;131(34):12068-9
nucleoside oQ  107865-20-3   Nucleoside Q/*analogs & derivatives. J Biol Chem 1987;262(8):3462
7-aminomethyl-7-deazaguanosine  66048-70-2 4H-Pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-5-(aminomethyl)-1,7-dihydro-7-beta-D-ribofuranosyl  Nucleoside Q/*analogs & derivatives. Nucleic Acids Res 7(1):231;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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