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Nucleotidyltransferases

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Definition: A class of enzymes that transfers nucleotidyl residues. EC 2.7.7.     
Examples N-Acylneuraminate Cytidylyltransferase; Choline-Phosphate Cytidylyltransferase; DNA Nucleotidyltransferases; Glucose-1-Phosphate Adenylyltransferase; Nicotinamide-Nucleotide Adenylyltransferase; 2',5'-Oligoadenylate Synthetase; Polynucleotide Adenylyltransferase; Rec A Recombinases; RNA Nucleotidyltransferases; Sulfate Adenylyltransferase; Transposases; Transposon Resolvases; UDPglucose-Hexose-1-Phosphate Uridylyltransferase; UTP-Glucose-1-Phosphate Uridylyltransferase; UTP-Hexose-1-Phosphate Uridylyltransferase; VDJ Recombinases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
aminoglycoside adenyltransferase AadD, methicillin-resistant Staphylococcus aureus  EC 2.7.7.-   *Bacterial Proteins *Nucleotidyltransferases. Med Dosw Mikrobiol. 2010;62(4):289-95
fucose-1-phosphate guanylyltransferase, mouse  EC 2.7.7.30   *Nucleotidyltransferases. J Immunol. 2011 Jun 1;186(11):6398-405
CTP-molybpterin cytiylyltransferase, E coli  EC 2.7.7.-   *Nucleotidyltransferases *Escherichia coli Proteins. J Biol Chem 2011 Jan 14;286(2):1400-8
cytidine monophosphate-3-deoxymannooctulosonate synthetase, Arabidopsis  EC 2.7.7.38   *Nucleotidyltransferases *Arabidopsis Proteins. J Biosci Bioeng 2009 Dec;108(6):527-9
GlmU protein, Mycobacterium tuberculosis  0   *Bacterial Proteins *Multienzyme Complexes Acetyltransferases Nucleotidyltransferases. Int J Biochem Cell Biol 2008;40(11):2560-71
VTC5 protein, Arabidopsis  EC 2.7.7.-   *Nucleotidyltransferases *Arabidopsis Proteins. J Biol Chem 2008 Jul 4;283(27):18483-92
NAADP synthase, Lytechinus pictus  EC 2.7.7.-   *Nucleotidyltransferases. Biochem J 2008 Apr 1;411(1):63-70
CGM1 protein, Trypanosoma brucei  EC 2.7.7.-   *Nucleotidyltransferases *Protozoan Proteins. Mol Biochem Parasitol 2007 Dec;156(2):246-54
thiamine diphosphate adenylyl transferase, E coli  EC 2.7.7.65   *Nucleotidyltransferases *Escherichia coli Proteins. BMC Biochem 2007;8:17
Glc-1-P thymidyltransferase, Streptomyces globisporus  EC 2.7.7.-   *Nucleotidyltransferases. J Am Chem Soc 2006 Oct 25;128(42):13694-5
Cid1 protein, S pombe  EC 2.7.7.19   *Nucleotidyltransferases *Schizosaccharomyces pombe Proteins. Mol Cell Biol 2000 May;20(9):3234-44
3,4-dihydroxybenzoic acid-AMP ligase, Bacillus anthracis  EC 2.7.7.-   *Nucleotidyltransferases. Biochemistry 2007 Apr 3;46(13):4147-57
Pect1 protein, Arabidopsis  EC 2.7.7.14   *Nucleotidyltransferases *Arabidopsis Proteins. Plant Cell 2006 Dec;18(12):3370-85
mummy protein, Drosophila  EC 2.7.7.23   *Nucleotidyltransferases. Mech Dev 2006 Jun;123(6):487-99
UDP-sugar pyrophosphorylase, Arabidopsis  EC 2.7.7.-   *Nucleotidyltransferases *Arabidopsis Proteins. Planta 2006 Aug;224(3):520-32
Rngtt protein, mouse  EC 3.1.3.33   *Nucleotidases *Nucleotidyltransferases. Cell Biochem Funct 2006 Mar-Apr;24(2):95-102
Thg1 protein, S cerevisiae  EC 2.7.7.-   *Nucleotidyltransferases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2005 Sep;25(18):8191-201
REV1 protein, Arabidopsis  EC 2.7.7.-   *Nucleotidyltransferases *Arabidopsis Proteins. Plant Physiol 2005 Jun;138(2):870-81
MOCS3 protein, human  EC 2.7.7.-   *Nucleotidyltransferases *Sulfurtransferases. Biochemistry 2005 May 31;44(21):7912-20
RDE-3 protein, C elegans  EC 2.7.7.-   *Nucleotidyltransferases *Caenorhabditis elegans Proteins. Curr Biol 2005 Feb 22;15(4):378-83
MoeB protein, E coli  EC 2.7.7.-   *Nucleotidyltransferases *Escherichia coli Proteins.
glnK protein, E coli  EC 2.7.7   *Nucleotidyltransferases *Escherichia coli Proteins *PII Nitrogen Regulatory Proteins.
Rev1l protein, mouse  EC 2.7.7.-   *Nucleotidyltransferases. Nucleic Acids Res 2005;33(1):356-65
alpha-d-glucopyranosyl-1-phosphate thymidylyltransferase, Streptomyces globisporus  EC 2.7.7.-   *Nucleotidyltransferases. J Nat Prod 2004 Feb;67(2);206-13
JAR1 protein, Arabidopsis  EC 2.7.7.-   *Nucleotidyltransferases *Arabidopsis Proteins. Plant Cell 2002 Jun;14(6):1405-15
D,D heptose 7-phosphate kinase-D,D-heptose 1-phosphate adenylyltransferase, E coli  EC 3.1.3.-   *Multienzyme Complexes *Nucleotidyltransferases *Phosphotransferases (Alcohol Group Acceptor). J Bacteriol 2002 Jan;184(2):363-9
aadA8 protein, Enterobacter aerogenes  EC 2.7.7.-   *Bacterial Proteins *Nucleotidyltransferases. Antimicrob Agents Chemother 2001 Oct;45(10):2961-4
MxcG protein, Stigmatella aurantiaca  EC 2.7.7.-   *Bacterial Proteins *Nucleotidyltransferases. Proc Natl Acad Sci U S A 2001 Sep 25;98(20):11136-41
2-C-methyl erythritol 4-phosphate cytidylyltransferase  EC 2.7.7.-   *Nucleotidyltransferases. Bioorg Med Chem 2001 Jun;9(6):1467-77
lipoate activating enzyme  EC 2.7.7.-   *Nucleotidyltransferases. J Biol Chem 2001 Aug 3;276(31):28819-23
signal recognition particle RNA 3'-adenylating enzyme  EC 2.7.7.-   *Nucleotidyltransferases. J Biol Chem 2001 Jun 15;276(24):21791-6
REV1 protein, human  EC 2.7.7.-   *Nuclear Proteins *Nucleotidyltransferases. J Biol Chem 2001 May 4;276(18):15051-8
Ant(4')-Ia protein, Staphylococcus aureus  EC 2.7.7.-   *Bacterial Proteins *Nucleotidyltransferases Drug Resistance, Microbial. J Antimicrob Chemother 1999 Feb;43(2):253-9
aminocyclitol adenylyltransferase  EC 2.7.7.-   *Nucleotidyltransferases.
aminoglycoside 4'-adenylyltransferase  EC 2.7.7.-   *Nucleotidyltransferases.
4,4''-aminoglycoside nucleotidyltransferase  EC 2.7.7.-   *Nucleotidyltransferases.
glucose-1-phosphate guanylyltransferase  EC 2.7.7.34   *Nucleotidyltransferases. Eur J Biochem 2000 Dec;267(23):6866-74
cobY protein, Methanobacterium thermoautotrophicum  EC 2.7.7.-   *Nucleotidyltransferases *Archaeal Proteins. J Bacteriol 2000 Aug;182(15):4227-33
ThiF protein, E coli  EC 2.7.7.-   *Nucleotidyltransferases *Escherichia coli Proteins. J Bacteriol 1993 Feb;175(4):982-92
aadA6 protein, Pseudomonas aeruginosa  EC 2.7.7.-   *Bacterial Proteins *Nucleotidyltransferases. Biochim Biophys Acta 1999 Dec 23;1489(2-3):445-51
4-diphosphocytidyl-2-C--methylerythritol synthase  EC 2.7.7.-   *Nucleotidyltransferases. Proc Natl Acad Sci U S A 1999 Oct 12;96(21):11758-63
Rep75 protein, Pyrococcus abyssi  0   *Nucleotidyltransferases *DNA Ligases *Archaeal Proteins. Mol Microbiol 1999 Aug;33(3):537-45
ATP-dependent capping enzyme, chimeric  0   *Nucleotidyltransferases *DNA Ligases *Recombinant Fusion Proteins. Nucleic Acids Res 1999 Aug 15;27(16):3253-8
NAD - penicillamine ADP transferase  EC 2.7.7.-   *Nucleotidyltransferases. J Biol Chem 1999 Jan 8;274(2):795-800
mRNA capping enzyme, Kluyveromyces lactis  EC 2.7.7.-   *Methyltransferases *Nucleotidyltransferases *Acid Anhydride Hydrolases. Plasmid 1998 Nov;40(3):243-6
WbpW protein, Pseudomonas aeruginosa  0   *Bacterial Proteins *Multienzyme Complexes Mannose-6-Phosphate Isomerase Nucleotidyltransferases. Mol Microbiol 1998 Sep;29(6):1419-34
GDP-L-fucose pyrophosphorylase  EC 2.7.7.-   *Nucleotidyltransferases. J Biol Chem 1998 Nov 13;273(46):30165-74
mat1 maturase  EC 2.7.7.-   *Nucleotidyltransferases RNA Splicing. Mol Biol Evol 1998 Jan;15(1):76-86
CEL-1 protein, C elegans  EC 3.1.3.33   *Nucleotidyltransferases *Acid Anhydride Hydrolases *Caenorhabditis elegans Proteins. Cell 1997 Jun 13;89(6):867-73
RibC protein, bacteria  EC 2.7.-   *Bacterial Proteins *Nucleotidyltransferases *Phosphotransferases (Alcohol Group Acceptor) Bacillus subtilis Bacterial Proteins. Mol Gen Genet 1997 Mar 18;254(1):81-4
REV1 protein, S cerevisiae  EC 2.7.7.-   *Nucleotidyltransferases *Saccharomyces cerevisiae Proteins. Nature 1996 Aug 22;382(6593):729-31
ManB protein, bacteria  EC 2.7.7.-   *Bacterial Proteins *Mannose-6-Phosphate Isomerase *Multienzyme Complexes *Nucleotidyltransferases. Int J Biol Macromol 1994 Dec;16(6):287-9
Ap(4)A phosphorylase II protein, Kluyveromyces lactis  EC 2.7.7.-   *Fungal Proteins *Nucleotidyltransferases. Biochim Biophys Acta 1994 Nov 22;1219(3):719-23
dTDP-D-glucose synthase  EC 2.7.7.-   *Mannose-6-Phosphate Isomerase *Nucleotidyltransferases ATP-Binding Cassette Transporters. J Bacteriol 1994 Jan;176(1):92-9
phosphomannose isomerase-guanosine diphospho-D-mannose pyrophosphorylase  134688-81-6   *Bacterial Proteins *Mannose-6-Phosphate Isomerase *Multienzyme Complexes *Nucleotidyltransferases. Biochim Biophys Acta 1993 Mar 20;1172(3):329-31
CTP-CMP-3-deoxynonulosonate cytidyltransferase  EC 2.7.7.-   *Nucleotidyltransferases. J Biol Chem 1993 Feb 5;268(4):2640-8
AadS protein, Bacteroides erm transposon, Tn4551  EC 2.7.7.-   *Nucleotidyltransferases. Mol Microbiol 1992 Aug;6(16):2287-97
actinomycin synthetase I  EC 2.7.7.-   *Nucleotidyltransferases. J Biol Chem 1992 Jun 15;267(17):11745-52
reovirus protein lambda2  0   *Nucleotidyltransferases *Viral Core Proteins RNA Caps. Virology 1991;185(1):376
cobinamide phosphate guanylyltransferase  EC 2.7.7.-   *Nucleotidyltransferases Multienzyme Complexes Vitamin B 12. J Bacteriol 1991;173(19):6052
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