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Omeprazole

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Definition: A highly effective inhibitor of gastric acid secretion used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits the H(+)-K(+)-ATPase (H(+)-K(+)-EXCHANGING ATPASE) in the proton pump of GASTRIC PARIETAL CELLS.     
Pharmacological Action Anti-Ulcer Agents; Enzyme Inhibitors 		Other names Esomeprazole; H 16868; H 168 68; Prilosec; Nexium; H 168-68Drugs* : PRILOSEC; NEXIUM; ESOMEPRAZOLE MAGNESIUM; OMEPRAZOLE MAGNESIUM; PRILOSEC OTC; OMEPRAZOLE; NEXIUM IV; VIMOVO
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
AGN 201904  0   Omeprazole/*analogs & derivatives. Aliment Pharmacol Ther 2008 Jul;28(2):187-99
omeprazole, sodium bicarbonate drug combination  0   *Omeprazole *Sodium Bicarbonate Drug Combinations.
Pharma Action Proton Pump Inhibitors 		Drugs R D. 2004;5(4):234-5ZEGERID; ZEGERID OTC; OMEPRAZOLE AND SODIUM BICARBONATE; MAGNESIUM HYDROXIDE AND OMEPRAZOLE AND SODIUM BICARBONATE
TU 199  0   *Imidazoles Omeprazole/*analogs & derivatives. Methods Find Exp Clin Pharmacol 1999 Mar;21(2):115-22
SK&F 95601  103949-62-8   Omeprazole/*analogs & derivatives. J Med Chem 1989;32(8):1970
omeprazole acid  120003-84-1   Omeprazole/*analogs & derivatives. Drug Metab Dispos 1989;17(1):69
2-(2-ethylaminobenzylsulfinyl)-5,6-dimethoxybenzimidazole  108499-48-5   Omeprazole/*analogs & derivatives H(+)-K(+)-Exchanging ATPase/antagonists & inhibitors. Pharmacology 1988;36(5):289
omeprazole cyclic sulfenamide  102332-89-8   Omeprazole/*analogs & derivatives. Biochem Pharmacol 1988;37(5):843
omeprazole sulfone  88546-55-8   Omeprazole/*analogs & derivatives. J Chromatogr 1983;278(2):311
omeprazole sulfide  73590-85-9   Omeprazole/*analogs & derivatives. J Chromatogr 1983;278(2):311
timoprazole  57237-97-5   Omeprazole/*analogs & derivatives. Gut 1983;24(6):557

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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