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ψ 
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Ornithine

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Definition: An amino acid produced in the urea cycle by the splitting off of urea from arginine.  /biosyn /physiol permitted   
Examples Eflornithine 		Other names 2,5 Diaminopentanoic Acid; Ornithine, (L)-Isomer; Ornithine, (DL)-Isomer; Ornithine, (D)-Isomer; Ornithine Sulfate (1:1), (L)-Isomer; Ornithine Phosphate (1:1), (L)-Isomer; Ornithine Monohydrochloride, (DL)-Isomer; Ornithine Monohydrochloride, (D)-Isomer; Ornithine Monohydrobromide, (L)-Isomer; Ornithine Monoacetate, (L)-Isomer; Ornithine Hydrochloride, (L)-Isomer; Ornithine Hydrochloride, (DL)-Isomer; Ornithine Hydrochloride, (D)-Isomer; Ornithine Dihydrochloride, (L)-Isomer; 2,5-Diaminopentanoic Acid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-alpha-(2-carboxyl)benzoyl-N5-(2-chloro-1-iminoethyl)ornithine amide  0   *Amidines Ornithine/*analogs & derivatives. J Med Chem. 2011 Oct 13;54(19):6919-35.
N-alpha-(2-carboxyl)benzoyl-N5-(2-fluoro-1-iminoethyl)ornithine amide  0   *Amidines Ornithine/*analogs & derivatives. J Med Chem. 2011 Oct 13;54(19):6919-35.
N-alpha-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide  0   Ornithine/*analogs & derivatives. J Immunol. 2011 Apr 1;186(7):4396-404
3-methylornithine  0   Ornithine/*analogs & derivatives. Nature. 2011 Mar 31;471(7340):647-50
N(alpha)-chloroacetylornithine  0   Ornithine/*analogs & derivatives. Amino Acids 2010 Apr;38(4):1155-64
Nalpha-9-fluorenylmethoxycarbonyl-Ndelta-sulfamoyl(benzyloxycarbonyl)-ornithine methyl ester  0   *Sulfonamides Ornithine/*analogs & derivatives. Amino Acids 2010 Mar;38(3):691-700
JBIR 16  0   *Benzamides Ornithine/*analogs & derivatives. J Antibiot (Tokyo) 2009 Oct;62(10):601-3
HHH syndrome  0   *Hyperammonemia *Urea Cycle Disorders, Inborn Ornithine/deficiency.
delta-cyano-L-ornithine  0   Ornithine/*analogs & derivatives. J Org Chem. 2008 Feb 1;73(3):1025-30
carbocyclic sinefungin  0   Adenosine/*analogs & derivatives Ornithine/*analogs & derivatives. J Org Chem 2006 May 26;71(11):4164-9
sagittamide B  0   Ornithine/*analogs & derivatives Valine/*analogs & derivatives. Org Lett 2005 May 26;7(11):2281-4
sagittamide A  0   Ornithine/*analogs & derivatives Valine/*analogs & derivatives. Org Lett 2005 May 26;7(11):2281-4
(4-amino-5-(4-(4-(2,4-dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido)tetrahydro-2H-4-pyranoylcarbonyl)piperazino)-5-oxopentyl)(trimethyl)ammonium  0   *Sulfonamides Ornithine/*analogs & derivatives Receptor, Bradykinin B2/antagonists & inhibitors. J Pharmacol Exp Ther 2005 Nov;315(2):616-23
furornithine  0   *Furans Ornithine/*analogs & derivatives. J Biol Chem 2004 Dec 24;279(52):54173-84
N(delta)-carboxymethylornithine  0   Ornithine/*analogs & derivatives. J Biol Chem 2004 Dec 24;279(52):54173-84
SLC25A2 protein, human  0   *Amino Acid Transport Systems, Basic Ornithine.
Slc25a15 protein, mouse  0   *Membrane Transport Proteins Ornithine.
N(alpha)-(4-(5-(2,4-diaminopteridin-6-yl)pent-1-yn-4-yl)benzoyl)-N(delta)-hemiphthaloylornithine  0   *Pteridines Ornithine/*analogs & derivatives. J Med Chem 2002 Apr 1;45(8):1690-6
N(alpha)-(4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)-N(delta)-hemiphthaloylornithine  0   *Quinazolines Ornithine/*analogs & derivatives. J Med Chem 2002 Apr 1;45(8):1690-6
4-hydroxyornithine  0   Ornithine/*analogs & derivatives. Org Lett 2001 Oct 4;3(20):3153-5
N(5)-(4-(5-amino-5-carboxypentyl)pyridino(2,3-d)imidazol-2-yl)ornithinate  0   *Imidazoles Ornithine/*analogs & derivatives. J Biol Chem 2001 Jun 29;276(26):23405-12
N(5)-(4-(5-amino-5-carboxypentyl)azepino(2,3-d)-5,6,7,8,8a-pentahydro-6,7-dihydroxyimidazol-2-yl)ornithinate  0   *Azepines Ornithine/*analogs & derivatives. J Biol Chem 2001 Jun 29;276(26):
N(omega)-acetyl-N(omega)-hydroxyornithine  0   Ornithine/*analogs & derivatives. Org Lett 2001 Feb 22;3(4):519-21
ornithinoalanine  0   *Alanine *Dipeptides *Ornithine. J Agric Food Chem 1999 Mar;47(3):939-44
N(delta)-(4,5-dihydrothiazol-2-yl)ornithine  0   *Thiazoles Ornithine/*analogs & derivatives Nitric Oxide Synthase/antagonists & inhibitors. Bioorg Med Chem 1999 Sep;7(9):1787-96
2-amino-6-(2-((4-amino-4-carboxybutyl)amino)-6,7-dihydroxy-4,5,6,7,8,8a-hexahydroimidazo(4,5-b)azepin-4-yl)hexanoic acid  0   *Azepines Ornithine. Bioorg Med Chem 1999 Jun;7(6):1081-8
N(5)-(1-imino-3-butenyl)ornithine  0   Ornithine/*analogs & derivatives Nitric Oxide Synthase/antagonists & inhibitors. J Biol Chem 1998 Apr 10;273(15):8882-9
1',2'-dioleoyl-sn-glycero-3'-succinyl-1,6-hexanediol ornithiine conjugate  0   *Lipids Ornithine/*analogs & derivatives. Biochem Biophys Res Commun 1998 Jan 6;242(1):141-5
1,2-dioleoyl-sn-glycero-3-succinyl-2-hydroxyethyl disulfide ornithine conjugate  0   *Lipids Ornithine/*analogs & derivatives. Biochem Biophys Res Commun 1998 Jan 6;242(1):141-5
N(delta)-(5-methyl-4-oxo-2-imidazolin-2-yl)ornithine  149204-50-2   *Imidazoles Ornithine/*analogs & derivatives. Biosci Biotechnol Biochem 1997 Jun;61(6):1007-10
argpyrimidine  0   *Pyrimidines Ornithine/*analogs & derivatives. Arch Biochem Biophys 1997 Aug 1;344(1):29-36
N alpha-(4-amino-4-deoxy-10-methylpteroyl)-4,4-difluoroornithine  0   Ornithine/*analogs & derivatives. J Med Chem 1996 Jun 21;39(13):2536-40
4-fluoroornithine  0   Ornithine/*analogs & derivatives. Biochem Pharmacol 1995 Oct 26;50(9):1433-43
PT 619  0   *Quinazolines Ornithine/*analogs & derivatives. Mol Pharmacol 1995 Oct;48(4):758-65
N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L-ornithine  113857-87-7   *Pterins Ornithine/*analogs & derivatives. Adv Exp Med Biol 1993;338:461-4
ornithine alpha-ketoisocaproate  0   *Keto Acids Ornithine/*analogs & derivatives. Am J Clin Nutr 1993 Jun;57(6):889-96
2,4-dinitrophenylornithine  10457-27-9   *Dinitrobenzenes Ornithine/*analogs & derivatives. Immunol Lett 1992 Jul;33(2):139-44
N-(alpha)-(N,N-dimethylcarbamoyl)-alpha-azaornithine 4-nitrophenyl ester  142181-98-4   *Aza Compounds Ornithine/*analogs & derivatives. Farmaco 1991 Dec;46(12):1517-29
N(alpha)-(N,N-dimethylcarbamoyl)-alpha-azaornithine phenyl ester  142181-97-3   *Aza Compounds Ornithine/*analogs & derivatives. Farmaco 1991 Dec;46(12):1517-29
PotE protein, E coli  0   *Antiporters *Escherichia coli Proteins Ornithine Putrescine. J Biol Chem 1991;266(31):20992
5,8-dideazapteroylornithine  118675-83-5   Ornithine/*analogs & derivatives. Arch Biochem Biophys 1990;281(2):198
N(G)-iminoethylornithine  36889-13-1   Ornithine/*analogs & derivatives Nitric Oxide Synthase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Biochem J 1990;269(1):207
S-(2-ornithylamino-4-methoxy-5-(1'-methyl-4'-piperidylamino)carboxyphenyl)glutathione  129596-89-0   Glutathione/*analogs & derivatives Ornithine/*analogs & derivatives. Mol Pharmacol 1990;37(6):983
staphyloferrin A  127902-98-1 Butanedioic acid, 2,2'-((1-carboxy-1,4-butanediyl)bis(imino(2-oxo-2,1-ethanediyl)))bis(2-hydroxy)  *Citrates Ornithine/*analogs & derivatives Siderophores. FEMS Microbiol Lett 1990;55(1-2):201
5,8,10-trideaza-5,6,7,8-tetrahydropteroylornithine  118537-34-1   *Pterins Ornithine/*analogs & derivatives. J Med Chem 1989;32(3):709
5-fluoromethylornithine  116292-10-5   Ornithine/*analogs & derivatives Ornithine-Oxo-Acid Transaminase/antagonists & inhibitors. Biochem J 1988;253(2):481
ornithine containing aminolipid  0   *Lipids Ornithine/*analogs & derivatives Thiobacillus. Biochem Biophys Res Commun 1987;42(3):925
2-amino-5-iodoacetamidovaleric acid  63984-35-0   Ornithine/*analogs & derivatives Arginase/antagonists & inhibitors. Contraception 1986;33(6):597
N(5)-(1-carboxyethyl)ornithine  104537-93-1   Ornithine/*analogs & derivatives. J Bacteriol 1986;167(2):522
N(2)-succinylornithine  99590-80-4   *Succinates Ornithine/*analogs & derivatives. J Bacteriol 1985;164(2):882
octicidine  65370-68-5   Ornithine/*analogs & derivatives Ornithine Carbamoyltransferase/antagonists & inhibitors. Biochem J 1985;228(2):347
ornithine transporter  0   *Amino Acid Transport Systems, Basic Ornithine. FEBS Lett 1984;170(1):131
delta-N-acetyl-delta-N-hydroxy-L-ornithine  18928-01-3   Ornithine/*analogs & derivatives. Biochim Biophys Acta 1981;657(2):313
delta-methylornithine  0   Ornithine/*analogs & derivatives. Anal Biochem 1980;104(2):343
N-delta-chloroacetyl-L-ornithine  20584-81-0   Ornithine/*analogs & derivatives. Arch Biochem Biophys 1980;204(1):234
alpha-methylornithine  48047-94-5 ornithine, 2-methyl  Ornithine/*analogs & derivatives.
Pharma Action Antineoplastic Agents 		Biochem Biophys Res Commun 86(2):312;1979; Biochim Biophys Acta 520(2):291;1978; C R Acad Sci (D) (Paris) 286:1215;1978; Exp Cell Res 115(2):387;1978; Exp Cell Res 119(1):63;1979; Experientia 1980;36(4):409; J Antibiot (Tokyo) 29(3):221;1976; J Med Chem 17(4):447;1974
N(delta)-acetylornithine  2185-16-2 N(5)-acetyl-L-ornithine  Ornithine/*analogs & derivatives. Biochim Biophys Acta 587(4):638;1979
phaseolotoxin  62249-77-8   Ornithine/*analogs & derivatives Ornithine Carbamoyltransferase. Biochem Biophys Res Commun 89(4):1361;1979
N(delta)-(phosphonoacetyl)-L-ornithine  63446-55-9   Ornithine/*analogs & derivatives. Arch Biochem Biophys 188(1):137;1978; Arch Int Physiol Biochim 1979;87(1):198; Eur J Biochem 1979;100(1):309; FEBS Lett 88:94;1978; J Biol Chem 254(14):6392;1979
desferritriacetylfusigen  20186-12-3 Acetamide, N,N',N''-(7,19,31-trihydroxy-10,22,34-trimethyl-2,8,14,20,26,32-hexaoxo-1,13,25-trioxa-7,19,31-triazacyclohexatriaconta-9,21,33-triene-3,15,27-triyl)tris-, (3S-(3R*,9Z,15R*,21Z,27R*,33Z))  Ornithine/*analogs & derivatives. J Antibiotics 30(2):125;1977
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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