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Osmotic Fragility

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Definition: RED BLOOD CELL sensitivity to change in OSMOTIC PRESSURE. When exposed to a hypotonic concentration of sodium in a solution, red cells take in more water, swell until the capacity of the cell membrane is exceeded, and burst.  do not coord with ERYTHROCYTES since this is defined in terms of erythrocytes; NIM    Other names Saline Fragility; Fragility, Saline; Fragility, Osmotic

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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