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Oxamniquine

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Definition: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martidale, The Extra Pharmacopoeia, 31st ed, p121)     
Pharmacological Action Schistosomicides
Other names UK4271; UK 4271; UK-4271; OxaminiquineDrugs* : VANSIL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
technetium Tc 99m oxamniquine  0   *Organotechnetium Compounds Oxamniquine/*analogs & derivatives. J Nucl Biol Med 1994 Dec;38(4 Suppl 1):109-12
desoxyoxamniquine  21738-41-0 1,2,3,4-tetra- hydro-6-methyl-N-(1-methylethyl)-7-nitro-2- quinolinemethanamine  Oxamniquine/*analogs & derivatives. Xenobiotica 1979;9(5):323

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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