encyclopedia of medical concepts
ψ 

Oxazoles

More information in Books or onNLM PubMed
Definition: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.  includes oxazolines, oxazolidines   
Examples Aminorex; Dimethadione; Fura-2; Muscimol; Oxadiazoles; Oxazolidinones; Oxazolone; Pemoline; Trimethadione 		Other names 1,3 Oxazolium 5 Oxides; Munchnones; 1,3-Oxazolium-5-Oxides
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(2,4-hexadienoyl)-7-(2-(5-methyl-2-(5-methylhexen-1-yl)oxazol-4-yl)ethoxy)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid  0   *Isoquinolines *Oxazoles PPAR gamma/agonists. Bioorg Med Chem. 2012 Jan 15;20(2):1060-75.
2-(2'-naphthyl)-5-(2'-naphthyl)-2-acetyl-2,3-dihydro-1,3,4-oxadiazoline  0   *Naphthalenes *Oxazoles. Bioorg Med Chem. 2012 Jan 15;20(2):903-9.
di(2-(5-phenyloxazolyl))benzene  0   *Oxazoles *Benzene Derivatives. Radiats Biol Radioecol. 2011 Nov-Dec;51(6): 660-9
MK-3328  0   *Oxazoles *Pyridines. Nucl Med Biol. 2011 Nov;38(8):1193-203.
KR33426  0   *Guanidines *Oxazoles Lupus Erythematosus, Systemic/drug therapy. Eur J Pharmacol. 2011 Oct 15;668(3):459-66
MDS 11  0   *Oxazoles. Biochem Pharmacol. 2011 Dec 15;82(12):1832-42.
MDS-11P compound  0   *Oxazoles *Phosphoric Acid Esters. Biochem Pharmacol. 2011 Dec 15;82(12):1832-42.
texaline  0   *Oxazoles *Pyridines Antitubercular Agents. Chemistry. 2011 Aug 29;17(36):10113-22
CP2-disorazole C1  0   *Oxazoles *Macrolides. Org Lett. 2011 Aug 5;13(15):4088-91
tert-butyl-4-((3-nitrophenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate  0   *Oxazoles. Life Sci. 2011 Nov 21;89(21-22):786-94
N1-(2-(2,3-dihydroxyphenyl)-5-methyl-2-oxazoline-4-carboxamido)-N3-(2,3-dihydroxyphenyl)-1,3-diaminopropane  0   *Catechols *Oxazoles. Mar Biotechnol (NY). 2011 Jun;13(3):451-61.
8-(3-(4-chlorophenyl)prop-2-enoyl)-3-((3,4-dichlorophenyl)methyl)-1-oxa-3,8-diazaspiro(4.5)decan-2-one  0   *Oxazoles *Spiro Compounds. J Biol Chem 2011 Aug 19;286(33):29292-302
2-phenyl-2-oxazoline  0   *Oxazoles. Phys Chem Chem Phys. 2011 Jul 7;13(25):11892-904
2-methyl-2-oxazoline  0   *Oxazoles. Phys Chem Chem Phys. 2011 Jul 7;13(25):11892-904
5-phenyl oxazole  0   *Oxazoles. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3404-6
kabiramide K  0   *Oxazoles *Macrolides. J Nat Prod. 2011 May 27;74(5):1288-92
kabiramide J  0   *Oxazoles *Macrolides. J Nat Prod. 2011 May 27;74(5):1288-92
spoxazomicin C  0   *Oxazoles. J Antibiot (Tokyo). 2011 Apr;64(4):303-7
spoxazomicin B  0   *Oxazoles *Thiazoles. J Antibiot (Tokyo). 2011 Apr;64(4):303-7
spoxazomicin A  0   *Oxazoles *Thiazoles. J Antibiot (Tokyo). 2011 Apr;64(4):303-7
2-(((4-methoxyphenoxy)carbonyl)(1-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)ethyl)amino)acetic acid  0   *Oxazoles Glycine/*analogs & derivatives PPAR alpha/agonists PPAR gamma/agonists. Drug Metab Dispos 2011 Feb;39(2):228-38
CG 301269  0   *Oxazoles *Thiazolidines PPAR alpha/agonists PPAR gamma/agonists. Diabetes 2011 Feb;60(2):496-506
diazonamide B  0   *Heterocyclic Compounds with 4 or More Rings *Oxazoles. Org Lett. 2011 Feb 4;13(3):390-3
SSJ 127  0   *Oxazoles *Benzothiazoles. Bioorg Med Chem 2010 Nov 15;18(22):7804-8
poly(2-methyl-2-oxazoline-block-(2-isopropyl-2-oxazoline-co-2-butyl-2-oxazoline)-block-2-methyl-2-oxazoline)  0   *Oxazoles *Polymers. Macromol Biosci 2010 Aug 11;10(8):916-24
aristoxazole  0   *Oxazoles. J Nat Prod. 2010 Dec 27;73(12):1979-86
inthomycin C  0   *Oxazoles. Org Lett. 2010 Nov 19;12(22):5088-91
1-(4-(2-(5-methyl-2-p-tolyloxazol-4-yl)ethoxy)benzyl)piperidine-2-carboxylic acid  0   *Oxazoles *Pipecolic Acids PPAR alpha/agonists PPAR gamma/agonists. Mol Pharmacol 2010 Nov;78(5):877-85
enigmazole A  0   *Organophosphorus Compounds *Oxazoles *Macrolides. J Am Chem Soc. 2010 Aug 4;132(30):10278-85
3-fluoro-5-(2-(pyridin-2-yl)-7,8-dihydro-4H-oxazolo(4,5-c)azepin-5(6H)-yl)benzonitrile  0   *Azepines *Oxazoles Receptors, Metabotropic Glutamate/antagonists & inhibitors. J Med Chem 2010 Oct 14;53(19):7107-18
mycalolide A  0   *Oxazoles. Org Lett. 2010 Aug 6;12(15):3348-51
2-(4-aminophenyl)-2-oxazoline  0   *Oxazoles. J Mater Sci Mater Med. 2010 Mar;21(3):879-86
2-ethyl-2-oxazoline  0   *Oxazoles. J Mater Sci Mater Med. 2010 Mar;21(3):879-86
2,6-bis(tert-butylcarbamoyl-2-oxazolin-2-yl)pyridine  0   *Oxazoles *Pyridines Ligands. Inorg Chem 2010 Jun 7;49(11):4717-9
4-(2-hydroxybenzylidene)-2-methyloxazol-5(4H)-one  0   *Oxazoles. Chem Commun (Camb) 2010 Apr 28;46(16):2868-70
GIT 27NO compound  0   *Oxadiazoles *Oxazoles. Free Radic Biol Med 2010 Apr 15;48(8):1090-9
calyculin C  0   *Oxazoles Phosphoprotein Phosphatases/antagonists & inhibitors. Mar Drugs. 2010;8(1):122-72
L1H1-70TD compound  0   *Oxazoles. Nucleic Acids Symp Ser (Oxf) 2009;(53):231-2
2-(4-methoxyphenyl)-N-((1-(3-phenoxybenzyl)-1H-1,2,3-triazol-4-yl)methyl)oxazole-4-carboxamide  0   *Oxazoles *Triazoles. J Med Chem 2010 Apr 22;53(8):3389-95
2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid  0   *Oxazoles Glycine/*analogs & derivatives PPAR alpha/agonists. J Med Chem 2010 Apr 8;53(7):2854-64
1,3-oxazolidin-2-imine  0   *Imines *Oxazoles. J Org Chem. 2010 Jan 15;75(2):514-7
4-(5-methyloxazolo(4,5-b)pyridin-2-yl)-1,4-diazabicyclo(3.2.2)nonane  0   *Oxazoles *Azabicyclo Compounds. J Med Chem 2010 Feb 11;53(3):1222-37
5-aminooxazole  0   *Oxazoles. Org Lett. 2010 Feb 19;12(4):820-3
doxazolidine  0   *Oxazoles Doxorubicin/*analogs & derivatives. J Med Chem 2005 Dec 1;48(24):7648-57
(3,5-bis(4-fluorophenyl)tetrahydro-1H-oxazolo(3,4-c)oxazol-7a-yl)methanol  0   *Oxazoles. J Med Chem 2009 Dec 10;52(23):7537-43
2-methyl-6-(3-(2-phenyloxazol-4-ylmethoxy)propoxymethyl)benzoic acid  0   *Oxazoles *Benzoic Acids PPAR alpha/agonists. Acta Pharmacol Sin 2009 Jul;30(7):935-46
ethyl-4,5-dihydro-5,5-diphenylisoxazol-3-carboxylate  0   *Oxazoles. Clin Toxicol (Phila). 2009 Sep;47(8):792-7
CPUY013 compound  0   *Oxazoles *Fluoroquinolones DNA Topoisomerases, Type I/antagonists & inhibitors. Yao Xue Xue Bao 2008 Aug;43(8):811-8
poly(2-methyl oxazoline)-block polydimethylsiloxane-block-poly(2-methyl oxazoline)  0   *Oxazoles *Polymers. Pharm Res 2009 Jul;26(7):1711-7
aleglitazar  0   *Oxazoles *Thiophenes. Lancet. 2009 Jul 11;374(9684):126-35
3-(1-methylethyl)-9b-phenyl-(1,3)oxazolo(2,3-a)isoindole-2,5(3H,9bH)-dione  0   *Oxazoles *Isoindoles. J Endocrinol 2009 Jun;201(3):261-7
disorazole E1  0   *Oxazoles *Macrolides. Nat Prod Rep 2009 May;26(5):585-601
2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid  0   *Oxazoles *Propionic Acids. Drug Metab Dispos 2009 May;37(5):946-55
5,5-(dimethyl)-i-Pr-PHOX  0   *Oxazoles. Org Lett 2009 May 21;11(10):2201-4
9-desmethylkbiramide B  0   *Oxazoles *Peptides, Cyclic. J Nat Prod 2009 Apr;72(4):732-8
33-methyltetrahydrohalichondramide  0   *Oxazoles *Peptides, Cyclic. J Nat Prod 2009 Apr;72(4):732-8
hemiphorboxazole A  0   *Heterocyclic Compounds with 4 or More Rings *Oxazoles. Org Lett 2009 May 7;11(9):1967-70
4,6-dinitrobenzo(d)isoxazole-3-carbonitrile  0   *Nitriles *Oxazoles. Org Biomol Chem. 2009 Mar 21;7(6):1137-46
UA 62784  0   *Oxazoles *Xanthones. Mol Cancer Ther 2009 Jan;8(1):36-44
3,5,5-trimethyloxazolidine 2,4-dione  0   *Oxazoles. Ann N Y Acad Sci 2008 Dec;1149():183-5
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy