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Oxytocics

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Definition: Drugs that stimulate contraction of the myometrium. They are used to induce LABOR, OBSTETRIC at term, to prevent or control postpartum or postabortion hemorrhage, and to assess fetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (ABORTIFACIENTS). Oxytocics used clinically include the neurohypophyseal hormone OXYTOCIN and certain prostaglandins and ergot alkaloids. (From AMA Drug Evaluations, 1994, p1157)  use no qualifiers for oxytocics when used to induce labor; note entry term OXYTOCIC EFFECT: use only for the oxytocic effect of a chemical substance    Other names Uterine Stimulants; Stimulants, Uterine; Effects, Oxytocic; Effect, Oxytocic; Drugs, Oxytocic; Agents, Oxytocic; Oxytocic Effects; Oxytocic Effect; Oxytocic Drugs; Oxytocic Agents
Substances having this pharmacologic action: dinoprost tromethamine; carbetocin; syntometrine; deaminooxytocin; Quipazine; Misoprostol; Sparteine; Vasotocin; Dinoprostone; Dinoprost; Oxytocin; Methylergonovine; Ergonovine; Ergotamine; Carboprost; carboprost tromethamine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
asoprisnil  0 benzaldehyde, 4-((11beta, 17beta)-17-methoxy-17-(methoxymethyl)-3-oxoestra-4, 9-dien-11beta-yl)-, 1-oxime  *Estrenes *Oximes Oxytocics. Steroids. 2003 Nov;68(10-13):1019-32
4-(17beta-methoxy-17alpha-(methoymethyl)-3-oxoestra-4,9-dien-11beta-yl)benzaldehyd-1-(E)-(O-(ethylamino)carbonyl)oxime  0   *Estrenes *Oximes Oxytocics. J Reprod Fertil Suppl 2001;57():249-54

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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