encyclopedia of medical concepts
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Oxytocin

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Definition: A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION.     
Pharmacological Action Oxytocics
See Also Receptors, Oxytocin 		Other names Ocytocin; Syntocinon; PitocinDrugs* : OXYTOCIN 5 USP UNITS IN DEXTROSE 5%; OXYTOCIN 10 USP UNITS IN DEXTROSE 5%; SYNTOCINON; OXYTOCIN; OXYTOCIN 20 USP UNITS IN DEXTROSE 5%; PITOCIN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-(2,3-dihydro-1H-inden-2-yl)-1-(1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl)-6-(1-methylpropyl)-2,5-piperazinedione  0   *Morpholines *Diketopiperazines Oxytocin/antagonists & inhibitors. J Med Chem. 2012 Jan 26;55(2):783-96.
mono-6-deoxy-6-oxytocinyl-beta-cyclodextrin 5  0   *Oxytocin *beta-Cyclodextrins Drug Carriers. Bioorg Med Chem Lett 2008 Mar 15;18(6):1855-8
conopressin-T, Conus tulipa  0   Oxytocin/*analogs & derivatives Mollusk Venoms. J Biol Chem 2008 Mar 14;283(11):7100-8
gamma-conopressin-vil, Conus villepinii  0   *Mollusk Venoms Oxytocin/*analogs & derivatives. Biochem J 2007 Jun 15;404(3):413-9
1,6-bis(L-alpha, beta-diaminopropionic acid) oxytocin  0   Oxytocin/*analogs & derivatives. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2006 Aug;23(4):818-21
2-(2,4-difluorophenyl)-2-(3-(2,3-dihydro-1H-inden-2-yl)-6-(2-methylpropyl)-2,5-dioxo-1-piperazinyl)-N,N-dimethylethanamide  0   *Indenes *Piperazines Oxytocin/antagonists & inhibitors. J Med Chem 2006 Jul 13;49(14):4159-70
oxytocin, d(CH2)5(1)-Tyr(OMe)(2)-Orn(8)  0   Oxytocin/*analogs & derivatives. Am J Obstet Gynecol 2006 Jan;194(1):252-60
F 792  0   *Peptides, Cyclic Oxytocin/antagonists & inhibitors. Bioorg Med Chem Lett 1999 Oct 4;9(19):2801-4
ANTAG III  0   Oxytocin/*analogs & derivatives Oxytocin/antagonists & inhibitors. J Soc Gynecol Investig 1998 Sep-Oct;5(5):251-4
ANTAG II  0   Oxytocin/*analogs & derivatives Oxytocin/antagonists & inhibitors. J Soc Gynecol Investig 1998 Sep-Oct;5(5):251-4
ANTAG I  0   Oxytocin/*analogs & derivatives Oxytocin/antagonists & inhibitors. J Soc Gynecol Investig 1998 Sep-Oct;5(5):251-4
carbetocin, desleucylglycine  0   Oxytocin/*analogs & derivatives. Eur J Pharmacol 1998 Aug 21;355(2-3):203-10
carbetocin, desglycyl  0   Oxytocin/*analogs & derivatives. Eur J Pharmacol 1998 Aug 21;355(2-3):203-10
mesotocin, Phe(2)  0   Oxytocin/*analogs & derivatives. Proc Natl Acad Sci U S A 1997 Nov 25;94(24):13339-44
VAP 259  0   Oxytocin/*analogs & derivatives Oxytocin/analogs & derivatives. Regul Pept 1996 Dec 3;67(2):69-73
oxytocin, 1-d(CH2)5-(2-O-methyl)Tyr-Thr(4)-Orn(8)-Tyr-NH2(9)  0   Oxytocin/*analogs & derivatives Ligands. Peptides 1996;17(2):251-6
tocinamide  13018-33-2   Oxytocin/*analogs & derivatives. Pharmacol Ther 1980;9(1):75
tocinoic acid  34330-23-9   Oxytocin/*analogs & derivatives. Fiziol Zh SSSR 1982;68(1):112
F 314  0   Oxytocin/*analogs & derivatives. Int J Cancer 1996 Jun 11;66(6):817-20
L 371257  0   *Piperidines *Benzoxazines Oxytocin/antagonists & inhibitors. J Med Chem 1995 Nov 10;38(23):4634-6
seritocin  0   Oxytocin/*analogs & derivatives. Int J Pept Protein Res 1995 May;45(5):482-7
F 382  0   Oxytocin/*analogs & derivatives. J Endocrinol 1995 Apr;145(1):97-103
F 372  0   Oxytocin/*analogs & derivatives. J Clin Invest 1995 Jan;95(1):13-9
phasvatocin  144334-53-2 Vasopressin, 4-L-asparagine-8-L-valine  Oxytocin/*analogs & derivatives. Proc Natl Acad Sci U S A 1994 Nov 8;91(23):11266-70
asvatocin  144334-52-1 Oxytocin, 4-L-asparagine-8-L-valine  Oxytocin/*analogs & derivatives. Proc Natl Acad Sci U S A 1994 Nov 8;91(23):11266-70
F 327  151272-15-0   Oxytocin/*analogs & derivatives. Br J Obstet Gynaecol 1993 Jun;100(6):581-6
oxytocin, Hmp(1)-Phe(2)-Hgn(4)-Dab(Ala)(8)  0   Oxytocin/*analogs & derivatives. Neuroendocrinology 1993;57(2):314-21
oxytocin, Pmp(1)-Trp(2)-Cys(6)-Arg(8)  0   Oxytocin/*analogs & derivatives. J Med Chem 1993 Mar 19;36(6):747-9
oxytocin, 3,2'-di-Me-Phe(2)  0   Oxytocin/*analogs & derivatives. Int J Pept Protein Res 1992 Aug;40(2):148-51
conopressin G  111317-91-0 Oxytocin, 2-L-phenylalanine-4-L-arginine-8-L-lysine  Oxytocin/*analogs & derivatives. Can J Physiol Pharmacol 1992 Feb;70(2):259-67
(phenylmethoxy)carbonylcysteinyl(phenylmethyl)-tyrosyl-isoleucine tert-butyl ester  52668-03-8   *Oligopeptides Oxytocin. Pept Res 1991 Nov-Dec;4(6):340-6
preproconopressin  0   *Protein Precursors Oxytocin/*analogs & derivatives. Proc Natl Acad Sci U S A 1992 May 15;89(10):4593-7
oxytocin, Mpa(1)-cyclo(Glu(4)-Lys(8))  125666-62-8   Oxytocin/*analogs & derivatives. J Med Chem 1992 May 1;35(9):1558-63
oxytocin, beta mercapto-beta,beta-cyclopentamethylenepropionic acid-Trp(2)-Arg(8)  133851-41-9   Oxytocin/*analogs & derivatives. Int J Pept Protein Res 1991 Aug;38(2):169-75
oxytocin, Trp(2)  37883-08-2   Oxytocin/*analogs & derivatives. Biochemistry 1992 Feb 18;31(6):1585-94
oxytocin, Pen(1)-Phe(2)-Thr(4)-Orn(8)  136429-81-7   Oxytocin/*analogs & derivatives. Int J Pept Protein Res 1991;38(1):32
oxytocin, MePhe(2)  3714-57-6   Oxytocin/*analogs & derivatives. Peptides 1991;12(1):113
oxytocin, -1-(beta-mercapto-(beta,beta-cyclopentamethylene)propionic acid)-Phe(Me)(2)-Thr(4)-Orn(8)  110220-69-4   Oxytocin/*analogs & derivatives. Peptides 1991;12(1):113
oxytocin, Pen(1)-(4-MePhe)(2)-Thr(4)-Orn(8)  106128-84-1   Oxytocin/*analogs & derivatives. Brain Res 1990;512(2):291
oxytocin, GlyNH2(10)  21687-84-3   Oxytocin/*analogs & derivatives. Neuroendocrinology 1990;51(4):437
1-deamino-2-Trp-4-Val-8-Orn-OT  92407-79-9   Oxytocin/*analogs & derivatives. Endocrinology 1990;126(2):728
oxytocin, Glu(NHNH2)(4)  127716-65-8   Oxytocin/*analogs & derivatives. Int J Pept Protein Res 1989;34(5):353
KB 5-21  0   Oxytocin/*analogs & derivatives.
Pharma Action Hormone Antagonists 		Eur J Pharmacol 1988;147(2):197
oxytocin, 1'-(1'-thio-4'-methylcyclohexane)acetic acid  113789-43-8   Oxytocin/*analogs & derivatives. Pol J Pharmacol Pharm 1987;39(3):303
oxytocin, 1'-(1'-methyl-4'-thiopiperidine)acetic acid  113789-44-9   Oxytocin/*analogs & derivatives. Pol J Pharmacol Pharm 1987;39(3):303
N-acetyloxytocin  10551-48-1   Oxytocin/*analogs & derivatives. J Biol Chem 1988;263(1):72
oxypressin  642-35-3   Oxytocin/*analogs & derivatives. Can J Physiol Pharmacol 1987;65(1):6
oxytocin, 1-(1-mercaptocyclohexaneacetic acid)-(OEt-Tyr)(2)-Orn(8)  77327-46-9   Oxytocin/*analogs & derivatives. Peptides 1986;7(4):695
oxytocin, His(4)  57735-87-2   Oxytocin/*analogs & derivatives. Neurosci Behav Physiol 1986;16(2):160
oxytocin, Phe(2)-Orn(8)  2480-41-3   Oxytocin/*analogs & derivatives. Am J Physiol 1985;249(5 Pt 2):H1001
oxytocin, Sar(7)  77225-24-2   Oxytocin/*analogs & derivatives. Neurosci Behav Physiol 1985;15(3):240
oxytocin, Gly-Lys-Arg  90685-16-8   Oxytocin/*analogs & derivatives Protein Precursors. J Biol Chem 1985;260(18):10118
oxytocin, Thr(4)-Gly(7)  60786-59-6   Oxytocin/*analogs & derivatives. Clin Exp Hypertens A 1984;6(10-11):1943
oxytocin, 1-penicillamyl-O-MeTyr(2)  89070-65-5   Oxytocin/*analogs & derivatives. Cesk Gynekol 1984;49(6):404
oxytocin,1-(beta-mercapto-(beta, beta-cyclopentamethylene)propionic acid)-Tyr(OMe)(2)-Orn(8)  77327-45-8   Oxytocin/*analogs & derivatives. Neurosci Lett 1984;48(2):161
oxytocin, 1-desaminopenicillamyl-Leu(2)  92444-08-1 Oxytocin, 1-(3-mercapto-3-methylbutanoic acid)-2-L-leucine-, (SP-4-2)  Oxytocin/*analogs & derivatives. Neurosci Lett 1984;48(2):161
oxytocin, 1-desaminopenicillamyl-Orn(8)  72915-18-5   Oxytocin/*analogs & derivatives. Neurosci Lett 1984;48(2):161
nacartocin  77727-10-7   Oxytocin/*analogs & derivatives Natriuresis/drug effects. Endocrinol Exp (Bratisl) 1984;18(2):117
oxytocin, (1-(2-hydroxy-3-mercaptopropionic acid))-Thr(4)-Gly(7)  60786-60-9   Oxytocin/*analogs & derivatives. Brain Res 1984;300(1):83
Glanduphen  80955-19-7   *Oxytocin *Vasopressins Drug Combinations. Arch Exp Veterinarmed 1984;38(2):133
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