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Pactamycin

More information in Books or onNLM PubMed
Definition: Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.     
Pharmacological Action Antibiotics, Antineoplastic; Protein Synthesis Inhibitors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5''-fluoropactamycin  0   Pactamycin/*analogs & derivatives. J Antibiot (Tokyo) 1994 Dec;47(12):1456-65
8''-hydroxypactamycin  104820-97-5 Benzoic acid, 2-hydroxy-6-methyl-, (4-amino-3-(((dimethylamino)carbonyl)amino)-1,2-dihydroxy-5-((3-(hydroxyacetyl)phenyl)amino)-3-(1-hydroxyethyl)-2-methylcyclopentyl)methyl ester, (1S-(1alpha,2beta,3alpha,3(R*),4alpha,5beta))  Pactamycin/*analogs & derivatives. J Antibiot (Tokyo) 1986;39(8):1086
cranomycin  11005-94-0   Pactamycin/*analogs & derivatives. J Antibiot (Tokyo) 1986;39(8):1086

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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