encyclopedia of medical concepts
ψ 
ψ 
ψ 
ψ 

Pancreatic Polypeptide

More information in Books or onNLM PubMed
Definition: A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.     
Pharmacological Action Gastrointestinal Agents; Hormones 		Other names Pancreatic Prohormone; Pancreatic Polypeptide Hormone; Pancreatic Polypeptide (PP)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PP 1420  0   Pancreatic Polypeptide/*analogs & derivatives. Br J Clin Pharmacol. 2012 Feb;73(2):232-9.
PPY2 protein, human  0   *Pancreatic Polypeptide. Genomics 2000 Mar 15;64(3):318-23
skin peptide tyrosine-tyrosine  0   *Pancreatic Polypeptide. Proc Natl Acad Sci U S A 1994 Oct 25;91(22):10295-9
gut PLY, Torpedo marmorata  0   *Pancreatic Polypeptide. Biochem Soc Trans 1994 Feb;22(1):6S
pancreatic polypeptide, salmon  107949-92-8   *Pancreatic Polypeptide Salmonidae. Biochem Biophys Res Commun 1986;141(3):1084
PPY protein, human  0   *Pancreatic Polypeptide *Protein Precursors. J Biol Chem 1984;259(23):14702
pancreatic eicosapeptide  0   *Pancreatic Polypeptide *Peptide Fragments Protein Precursors. Proc Natl Acad Sci USA 1984;81(3):708
pancreatic polypeptide (31-36)  0   *Pancreatic Polypeptide *Peptide Fragments. Diabetes 1982;31(2):178
receptors, pancreatic polypeptide-specific  0   *Receptors, Gastrointestinal Hormone Glycoproteins Pancreatic Polypeptide. Biochem Soc Trans 1981;9(1):31
pancreatic polypeptide, avian  58591-52-9   *Pancreatic Polypeptide. Endocrine Gut Pancreas WK170 I605e:133;1975; Gastroenterology 72(4):662;1977; Gastroenterology 74(1):294;1978; Gen Comp Endocrinol 34:421;1978; Histochemistry 42(4):377;1974

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy