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Parabens

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Definition: Methyl, propyl, butyl, and ethyl esters of p-hydroxybenzoic acid. They have been approved by the FDA as antimicrobial agents for foods and pharmaceuticals. (From Hawley's Condensed Chemical Dictionary, 11th ed, p872)  D25-26 qualif   
Pharmacological Action Food Preservatives; Preservatives, Pharmaceutical
Other names para-Hydroxybenzoic Acids; 4-Hydroxybenzoic Acids; para Hydroxybenzoic Acids; 4 Hydroxybenzoic Acids
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
juniferdin  0   *Parabens *Sesquiterpenes Protein Disulfide-Isomerases/antagonists & inhibitors. ACS Chem Biol 2011 Mar 18;6(3):
citrate, isopropyl alcohol, methylene blue, parabens drug combination  0   *Citrates *Methylene Blue *Parabens *2-Propanol Drug Combinations. J Infect 2010 Jan;60(1):36-43
phenylcarbinyl 5-O-(4-hydroxy)benozylapiofuranosyl-1-2-glucopyranoside  0   *Disaccharides *Parabens. Nat Prod Commun 2009 Apr;4(4):511-2
ratanhine  0   *Benzofurans *Parabens. J Am Chem Soc 2007 May 30;129(21):6716-7
isoquercitrin 6''-O-4-hydroxybenzoate  0   *Parabens Quercetin/*analogs & derivatives. Phytother Res 2006 Mar;20(3):200-5
sinapyl 4-hydroxybenzoate  0   *Parabens. Org Biomol Chem 2004 Oct 21;2(20):2888-90
3-nitro-4-hydroxybenzoate  0   *Nitro Compounds *Parabens. Protein Sci. 2003 Sep;12(9):1902-13
myrsinoic acid E  0   *Parabens *Terpenes. Biosci Biotechnol Biochem 2003 Sep;67(9):2038-41
heptylparaben  0   *Parabens. Int J Pharm. 2003 Oct 20;265(1-2):133-40
isobutylparaben  0   *Parabens. J Appl Toxicol 2002 Jul-Aug;22(4):219-26
dichloroisoeverninic acid  0   *Parabens. Chem Biol 2001 Jun;8(6):569-81
tagetenolone  0   *Parabens. J Agric Food Chem 2001 Mar;49(3):1228-32
tagetolone  0   *Parabens. J Agric Food Chem 2001 Mar;49(3):1228-32
noscomin  0   *Parabens *Phenanthrenes. J Nat Prod 1999 Mar;62(3):502-3
tetrafluoro-4-hydroxybenzoic acid  652-34-6   *Parabens. Biochemistry 1997 Nov 18;36(46):14192-201
methyl 4-hydroxy-3-(3'-methyl-2'-butenyl)benzoate  101511-34-6   *Parabens. J Nat Prod 1997 Mar;60(3):282-4
RPR 102359  0   *Parabens *Phenylenediamines Receptors, LDL/agonists. J Med Chem 1996 Aug 16;39(17):3343-56
cylindol B  159225-90-8   *Parabens *Phenyl Ethers. J Nat Prod 1994 Sep;57(9):1290-3
cylindrol A  0   *Parabens *Phenyl Ethers. J Nat Prod 1994 Sep;57(9):1290-3
proglobeflowery acid  146367-85-3 Benzoic acid, 4-hydroxy-3-methoxy-5-(3-methyl-2-butenyl)  *Parabens Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1992;27(11):837-40
methyl 4-hydroxy-5-iodo-2,3-dimethoxy-6-methylbenzoate  127761-05-1   Parabens. Int J Rad Appl Instrum (B) 1991;18(5):445
katoko  0   *Parabens *Thimerosal Drug Combinations. Acta Med Iugosl 1990;44(4):433
3,5-di-tert-butyl-4-hydroxybenzoic acid  1421-49-4   *Parabens. Food Chem Toxicol 1989;27(12):765
benzylparaben  94-18-8   *Parabens. Contact Dermatitis 1988;19(3):189
isobutyl-4-hydroxybenzoate  4247-02-3   *Parabens. Food Chem Toxicol 1985;23(6):575
4-hydroxybenzoic acid  99-96-7   *Parabens. Science 1983;221(4606):163
butylparaben  94-26-8   *Parabens. J Appl Bacteriol 1983;54(2):237
Grisaldon  8014-03-7   *Parabens Drug Combinations. Zahn Mund Kieferheilkd 67(6):579;1979
methylparaben  99-76-3   *Parabens.
Pharma Action Preservatives, Pharmaceutical
Arch Dermatol 113(10):1463;1977; J Chromatogr 148(2):453;1978; J Econ Entomol 67(2):147;1974; Zahn Mund Kieferheilkd 1979;67(6):579
ethyl-p-hydroxybenzoate  120-47-8   *Parabens. Acta Obstet Gynaecol Jap 22(2):94;1975
neomedrol-veriderm  78232-14-1 Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6alpha,11beta)-, mixture with butyl 4-hydroxybenzoate, methyl 4-hydroxybenzoate and neomycin sulfate (salt)  *Methylprednisolone *Neomycin Drug Combinations Parabens. Med Arh 29(6):641;1975; Med Arh 30(1):39;1976NEO-MEDROL ACETATE
Medrol Veriderm  78065-40-4   *Methylprednisolone Drug Combinations Parabens. Med Arh (Sarajevo) 29(6):641;1975; Med Arh (Sarajevo) 30(1):39;1976
2-hydroxy-5-carbomethoxybenzyloxyamine  38573-39-6 3-((aminooxy)methyl)-4-hydroxybenzoic acid methyl ester  *Parabens Histidine Decarboxylase/antagonists & inhibitors. Biochem Pharmacol 22(18):2253;1973
aspirin, 4-hydroxybenzoic acid propyl ester, drug combination  57762-41-1   *Aspirin *Parabens Drug Combinations. Czas Stomatod 29(9):793;1976; Int J Oral Surg 4:157;1975; J Dental Res 54(5):1082;1975; Sven Tandlak Tidskrift 66(5):475;1973
propylparaben  94-13-3 4-hydroxybenzoic acid, propyl ester  *Parabens.
Pharma Action Preservatives, Pharmaceutical
Dtsch Zahnaerztl Z 29(11):1018;1974; Oral Surg 43(1):32;1977; Zahn Mund Kieferheilkd 1979;67(6):579

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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