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Paraproteinemias

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Definition: A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.     
Examples Cryoglobulinemia; Heavy Chain Disease; Multiple Myeloma; POEMS Syndrome; Waldenstrom Macroglobulinemia 		Other names Plasma Cell Dyscrasias; Paraimmunoglobulinemias; Monoclonal Gammopathies; Gammopathy, Monoclonal; Gammapathy, Monoclonal; Plasma Cell Dyscrasia; Paraproteinemia; Paraimmunoglobulinemia; Gammopathies, Monoclonal; Monoclonal Gammapathy; Gammapathies, Monoclonal; Dyscrasias, Plasma Cell; Dyscrasia, Plasma Cell; Cell Dyscrasias, Plasma; Cell Dyscrasia, Plasma; Monoclonal Gammopathy; Monoclonal Gammapathies

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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