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Pentazocine

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Definition: The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)     
Pharmacological Action Adjuvants, Anesthesia; Analgesics, Opioid; Narcotic Antagonists; Narcotics 		Other names Lactate, Pentazocine; Hydrochloride, Pentazocine; Talwin; Pentazocine Lactate; Pentazocine Hydrochloride; Lexir; FortralDrugs* : TALWIN 50; TALWIN; TALACEN; ACETAMINOPHEN AND PENTAZOCINE HYDROCHLORIDE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
JO 2871  0   Pentazocine/*analogs & derivatives Ligands. Gut 2002 Oct;51(4):522-8
3'-iodopentazocine  0   Pentazocine/*analogs & derivatives Ligands. Eur J Pharmacol 1997 Mar 5;321(3):361-8
talwin Nx  126663-39-6   *Naloxone *Pentazocine Drug Combinations. JAMA 1986;256(18):2562PENTAZOCINE AND NALOXONE HYDROCHLORIDES; PENTAZOCINE AND NALOXONE HYDROCHLORIDE; TALWIN NX
pentazocine glucuronide  54763-91-6   Pentazocine/*analogs & derivatives. Z Rechtsmed 1985;95(2):123
4,6-ethano-3,4,4a,5,6,10b-hexahydro-2,5,6-trimethylbenzo(f)quinolin-8-ol  77502-66-0 3H-4,6-Ethanobenzo(f)quinolin-8-ol, 4a,5,6,10b-tetrahydro-2,5,6-trimethyl-, (4alpha,4abeta,5beta,6alpha,10bbeta)  Pentazocine/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1983;31(7):2520
5,7-ethano-4,5,5a,6,7,11b-hexahydro-2,6,7-trimethyl-1H-benzo(g)homoquinolin-9-ol  77502-64-8 5,7-Ethano-5H-naphth(2,1-b)azepin-9-ol, 1,4,5a,6,7,11b-hexahydro-2,6,7-trimethyl-, (5alpha,5abeta,6beta,7alpha,11bbeta)  Pentazocine/*analogs & derivatives. Chem Pharm Bull(Tokyo) 1983;31(7):2520
KF 1820  0   Pentazocine/*analogs & derivatives. Acta Med Okayama 1981;35(3):179

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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