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Pentobarbital

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Definition: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)     
Pharmacological Action Adjuvants, Anesthesia; GABA Modulators; Hypnotics and Sedatives 		Other names Mebubarbital; Mebumal; Monosodium Salt Pentobarbital; Sagatal; Pentobarbitone; Pentobarbital, Monosodium Salt; Pentobarbital Sodium; Nembutal; Ethaminal; Etaminal; DiabutalDrugs* : SODIUM PENTOBARBITAL; PENTOBARBITAL SODIUM; NEMBUTAL; NEMBUTAL SODIUM
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cyclopentobarbital  76-68-6   Pentobarbital/*analogs & derivatives. J Org Chem 2000 Mar 10;65(5):1569-73
1-(glucopyranosyl)pentobarbital  147839-07-4   Pentobarbital/*analogs & derivatives. Pharm Res 1994 Nov;11(11):1535-9
2-hydroxylamine-5-ethyl-5-sec-pentylbarbituric acid  102856-34-8   Pentobarbital/*analogs & derivatives. Methods Find Exp Clin Pharmacol 1988;10(4):267
benzobamil  7279-57-4   Pentobarbital/*analogs & derivatives. Sud Med Ekspert 1980;23(2):42
N-allylpentobarbital  99683-86-0   Pentobarbital/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 1985;50(2):209
N,N-diallylpentobarbital  95575-11-4   Pentobarbital/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 1985;50(2):209
4'-hydroxypentobarbitone  87079-96-7 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(4-hydroxy-1-methylbutyl)  Pentobarbital/*analogs & derivatives. Xenobiotica 1983;13(3):179
3'-hydroxypentobarbital  4241-40-1   Pentobarbital/*analogs & derivatives. J Chromatogr 1983;275(1):107
chloropent  39373-60-9   *Chloral Hydrate *Magnesium Sulfate *Pentobarbital. J Neurochem 1982;39(1):235

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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