Definition: A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.
coordinate with MITOCHONDRIAL PROTEINS or BACTERIAL PROTEINS if pertinent
Other names Elongation Factor Tu; eEF Tu; Factor Tu, Elongation; EF Tu; eEF-Tu; Protein Synthesis Elongation Factor Tu; Eucaryotic Elongation Factor Tu; EF-Tu