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Peroxides

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Definition: A group of compounds that contain a bivalent O-O group, i.e., the oxygen atoms are univalent. They can either be inorganic or organic in nature. Such compounds release atomic (nascent) oxygen readily. Thus they are strong oxidizing agents and fire hazards when in contact with combustible materials, especially under high-temperature conditions. The chief industrial uses of peroxides are as oxidizing agents, bleaching agents, and initiators of polymerization. (From Hawley's Condensed Chemical Dictionary, 11th ed)     
Pharmacological Action Oxidants
See Also Benzoyl Peroxide; Lipid Peroxides; Reactive Oxygen Species
Examples Hydrogen Peroxide; Superoxides
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
diacarperoxide S  0   *Peroxides *Terpenes. Nat Prod Commun. 2012 Jan;7(1):9-12
OZ 439  0   *Peroxides Adamantane/*analogs & derivatives. Proc Natl Acad Sci U S A 2011 Mar 15;108(11):4400-5
5-hydroxy-6-hydroperoxy-5,6-dihydrothymidine  0   *Peroxides Thymidine/*analogs & derivatives. J Phys Chem B 2010 Oct 7;114(39):12641-54
epimuqubilin A  0   *Peroxides *Sesquiterpenes. Mar Drugs 2010;8(3):429-37
hydrogen thioperoxide  0   *Peroxides. Phys Chem Chem Phys 2010 Aug 1;12(29):8387-97
ascorbylperoxide  0   *Peroxides Ascorbic Acid/*analogs & derivatives. J Pharmacol Exp Ther 2010 Jul;334(1):278-84
plakinic acid L  0   *Peroxides. Org Lett. 2010 Apr 2;12(7):1520-3
plakinic acid K  0   *Peroxides. Org Lett. 2010 Apr 2;12(7):1520-3
merulin C  0   *Peroxides. J Nat Prod. 2010 May 28;73(5):1005-7
merulin B  0   *Peroxides. J Nat Prod. 2010 May 28;73(5):1005-7
merulin A  0   *Peroxides. J Nat Prod. 2010 May 28;73(5):1005-7
peroxybicarbonic acid  0   *Bicarbonates *Peroxides. J Phys Chem A 2009 Aug 13;113(32):9138-49
chromium peroxide  0   *Peroxides *Chromium Compounds. Eur J Med Chem 2009 Oct;44(10):4162-8
plakinic acid J  0   *Acetic Acids *Peroxides. Angew Chem Int Ed Engl 2009;48(24):4367-71
plakinic acid I  0   *Acetic Acids *Peroxides. Angew Chem Int Ed Engl 2009;48(24):4367-71
4-isopropylpyridine hydroperoxide  0   *Peroxides *Pyridines. J Phys Chem B 2009 Apr 9;113(14):4555-9
1-butylnaphthalene-4-propionic acid endoperoxide  0   *Naphthalenes *Peroxides. Cell Biol Int 2008 Nov;32(11):1380-7
methyl peroxynitrite  0   *Nitrites *Peroxides. J Am Chem Soc 2008 Aug 20;130(33):11234-9
mycangimycin  0   *Peroxides *Acetic Acids. Science 2008 Oct 3;322(5898):63
urticic acid  0   *Fatty Acids, Monounsaturated *Peroxides. Arch Pharm Res 2008 Aug;31(8):999-1003
hydroxymethyl hydroperoxide  0   *Peroxides. J Chem Phys. 2008 May 7;128(17):174304
2-butanone peroxide  0   *Butanones *Peroxides. J Hosp Infect 2008 Mar;68(3):248-54
rembrant xtra comfort  0   *Peroxides. Am J Dent 2008 Feb;21(1):17-20
nite white excel 2Z  0   *Peroxides. Am J Dent 2008 Feb;21(1):17-20
OZ381  0   *Peroxides *Spiro Compounds Adamantane/*analogs & derivatives. Bioorg Med Chem Lett 2008 Mar 1;18(5):1555-8
OZ397  0   *Peroxides *Spiro Compounds Adamantane/*analogs & derivatives. Bioorg Med Chem Lett 2008 Mar 1;18(5):1555-8
Forte whitening agent  0   *Peroxides Tooth Bleaching. J Clin Dent 2007;18(4):126-30
1,2-dimethylethyl hydroperoxide  0   *Peroxides. J Dairy Sci 2007 Aug;90(8):3640-6
S-(fluoroformyl)O-(trifluoroacetyl) thioperoxide  0   *Hydrocarbons, Fluorinated *Peroxides. J Phys Chem A 2006 Aug 31;110(34):10201-5
lophine hydroperoxide  0   *Imidazoles *Peroxides. Luminescence 2007 Mar-Apr;22(2):72-6
1-(4-methoxy-3-(6-methoxy-3-acetylphenylperoxy)phenyl)ethanone  0   *Peroxides. Nat Prod Res 2007 Mar;21(3):203-10
magnesium peroxide  0   *Peroxides *Magnesium Compounds. Bioresour Technol 2007 Jan;98(2):478-83
7-hydroperoxymanool  0   *Diterpenes *Peroxides. Arch Pharm Res 2006 Oct;29(10):845-8
7-hydroperoxyeudesma-11-en-4-ol  0   *Peroxides *Sesquiterpenes. Arch Pharm Res 2006 Oct;29(10):845-8
triacetone triperoxide  0   *Heterocyclic Compounds, 1-Ring *Peroxides. J Forensic Sci 2004 Sep;49(5):935-8
plakorstatin 2  0   *Peroxides. J Nat Prod 2004 Sep;67(9);1611-3
plakorstatin 1  0   *Peroxides. J Nat Prod 2004 Sep;67(9);1611-3
arterolane  0   *Heterocyclic Compounds, 1-Ring *Peroxides *Spiro Compounds Antimalarials. Nature 2004 aug 19;430(7002):900-4
Colgate Simply White Night  0   *Peroxides Tooth Bleaching.
Pharma Action Tooth Bleaching Agents 		Am J Dent. 2003 Nov;16 Spec No():17B-21B
tasnemoxide C  0   *Peroxides *Terpenes. J Nat Prod 2004 Jan;67(1):112-4
tasnemoxide B  0   *Peroxides *Terpenes. J Nat Prod 2004 Jan;67(1):112-4
tasnemoxide A  0   *Peroxides *Terpenes. J Nat Prod 2004 Jan;67(1):112-4
2-cyano-2-propyl hydroperoxide  0   *Nitriles *Peroxides. J Am Chem Soc 2003 Sep 24;125(38):11532-8
andavadoic acid  0   *Heterocyclic Compounds, 1-Ring *Peroxides. J Nat Prod 2003 May;66(5);682-5
plakortolide I  0   *Heterocyclic Compounds, 2-Ring *Peroxides. J Nat Prod 2003 May;66(5);682-5
plakortolide H  0   *Heterocyclic Compounds, 2-Ring *Peroxides. J Nat Prod 2003 May;66(5);682-5
mycaperoxide H  0   *Peroxides *Terpenes. J Nat Prod 2003 Feb;66(2):289-91
Colgate Simply White Clear Whitening Gel  0   *Peroxides Complex Mixtures Dentifrices Tooth Bleaching.
Pharma Action Tooth Bleaching Agents 		Compend Contin Educ Dent 2002 Nov;23(11 Suppl 1):4-11
2-methyl-1-phenylprop-2-yl hydroperoxide  0   *Peroxides. J Am Chem Soc 2003 Apr 2;125(13):3678-9
bungein A  0   *Peroxides Phenylethyl Alcohol/*analogs & derivatives. J Asian Nat Prod Res 2002 Sep;4(3):165-9
yingzhaosu A  73301-54-9   *Peroxides *Sesquiterpenes Malaria Annonaceae. J Med Chem 2002 Oct 10;45(21):4732-6
N-acetyltryptophan methyl ester peroxide  0   *Peroxides Tryptophan/*analogs & derivatives. FEBS Lett 2002 Sep 11;527(1-3):289-92
tryptophan peroxide  0   *Peroxides Tryptophan/*analogs & derivatives. FEBS Lett 2002 Sep 11;527(1-3):289-92
6-epiplakortolide E  0   *Lactones *Peroxides. Org Lett 2002 Aug 8;4(16):2763-5
1,2-bis(methyldioxy)cyclododecane  0   *Cycloparaffins *Peroxides. J Med Chem 2002 Mar 14;45(6):1374-8
4-(tert-butylperoxymethyl)morpholine  0   *Morpholines *Peroxides. Bioorg Med Chem Lett 2001 Sep 3;11(17):2269-72
plakortolide F  0   *Peroxides. J Nat Prod 2001 Feb;64(2):262-4
epiplakinic acid F  0   *Peroxides. J Nat Prod 2001 Feb;64(2):262-4
plakinic acid F  0   *Peroxides. J Nat Prod 2001 Feb;64(2):262-4
bis(trimethylsilyl) peroxide  0   *Peroxides *Silanes. J Org Chem 2001 Jun 29;66(13):4713-8
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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