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Virulence Factors, Bordetella

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Definition: A set of BACTERIAL ADHESINS and TOXINS, BIOLOGICAL produced by BORDETELLA organisms that determine the pathogenesis of BORDETELLA INFECTIONS, such as WHOOPING COUGH. They include filamentous hemagglutinin; FIMBRIAE PROTEINS; pertactin; PERTUSSIS TOXIN; ADENYLATE CYCLASE TOXIN; dermonecrotic toxin; tracheal cytotoxin; Bordetella LIPOPOLYSACCHARIDES; and tracheal colonization factor.     
Examples Adenylate Cyclase Toxin; Pertussis Toxin
Other names Bordetella Virulence Factors; Virulence Determinant, Bordetella; Lymphocytosis Promoting Factor Hemagglutinin; Leukocytosis Promoting Factor Hemagglutinin; LP HA; LFP Hemagglutinin; Hemagglutinin, Leukocytosis-Promoting Factor; Factors, Bordetella Virulence; Factor-Hemagglutinin, Lymphocytosis-Promoting; Factor Hemagglutinin, Leukocytosis-Promoting; Determinant, Bordetella Virulence; Agglutinins, Pertussis; Pertussis Agglutinins; Lymphocytosis-Promoting Factor-Hemagglutinin; Leukocytosis-Promoting Factor Hemagglutinin; LFP-Hemagglutinin; Bordetella Virulence Determinant; Agglutinogen 2, Bordetella Pertussis; LP-HA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FHA protein, Bordetella bronchiseptica  0   *Virulence Factors, Bordetella *Adhesins, Bacterial Antigens, Bacterial. Infect Immun 2009 May;77(5):2136-46
FimN protein, Bordetella bronchiseptica  0   *Antigens, Bacterial *Virulence Factors, Bordetella *Fimbriae Proteins Fimbriae, Bacterial. Gene 2000 Oct 3;256(1-2):149-55
fim3 protein, Bordetella  0   *Antigens, Bacterial *Virulence Factors, Bordetella *Fimbriae Proteins Fimbriae, Bacterial. FEMS Microbiol Lett 1990 Jan 1;54(1-3):327-31
fim2 protein, Bordetella  0   *Antigens, Bacterial *Virulence Factors, Bordetella *Fimbriae Proteins Fimbriae, Bacterial. J Struct Biol 1996 Mar-Apr;116(2):264-9
fhaC protein, Bordetella pertussis  0   *Bacterial Outer Membrane Proteins Virulence Factors, Bordetella. J Bacteriol 1996 Feb;178(4):1053-60
tracheal colonization factor, Bordetella pertussis  0   *Bacterial Proteins *Virulence Factors, Bordetella. Mol Microbiol 1995 May;16(4):625-34
pertussis endotoxin  0   *Lipopolysaccharides *Virulence Factors, Bordetella Antigens, Bacterial Bordetella pertussis. Springer Semin Immunopathol 1993;15(2-3):205-15
pertactin  0   *Bacterial Outer Membrane Proteins *Virulence Factors, Bordetella Bordetella pertussis Bordetella bronchiseptica. Eur J Immunol 1991;21(5):1147
filamentous hemagglutinin adhesin, Bordetella pertussis  0   *Virulence Factors, Bordetella *Adhesins, Bacterial Antigens, Bacterial. Infect Immun. 2005 Aug;73(8):4960-71; Mol Microbiol 1990;4(5):787
dermonecrotic toxin, Bordetella  0   *Virulence Factors, Bordetella *Transglutaminases Bordetella. Microb Pathog 1989;6(5):361
tracheal cytotoxin, Bordetella pertussis  118013-66-4   *Peptidoglycan *Virulence Factors, Bordetella Cytotoxins. Biochemistry 1989;28(4):1744

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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