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Phenacetin

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Definition: A phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market. (From Smith and Reynard, Textbook of Pharmacology,1991, p431)     
Pharmacological Action Analgesics, Non-Narcotic 		Other names Acetophenetidin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Keganmin  0   *Aminopyrine *Caffeine *Phenacetin Drug Combinations. Guang Pu Xue Yu Guang Pu Fen Xi. 1997 Feb;17(1):123-5
vicedrin  0   *Ascorbic Acid *Ephedrine *Phenacetin Drug Combinations. Cesk Pediatr 1991;46(2):98
pircophen  8075-94-3   *Aminopyrine *Caffeine *Phenacetin Drug Combinations. Klin Med (Mosk) 1990;68(8):91
O-isopropyl acetaminophen  7146-61-4   Phenacetin/*analogs & derivatives. Xenobiotica 1990;20(12):1281
O-propyl acetaminophen  20367-32-2   Phenacetin/*analogs & derivatives. Xenobiotica 1990;20(12):1281
N-(pivaloyloxy)phenacetin  102725-57-5   Phenacetin/*analogs & derivatives. J Med Chem 1986;29(8):1424
aspirin, codeine, phenacetin, phenobarbital drug combination  52453-04-0   *Aspirin *Codeine *Phenacetin *Phenobarbital Drug Combinations. Eksp Med Morfol 1983;22(1):39
4-nitrosophenetole  3420-97-1   Phenacetin/*analogs & derivatives. Chem Biol Interact 1982;42(2):209
DP-neuralgen  86290-92-8 Benzoic acid, 2-(acetyloxy)-, mixt. with (S-(R*,S*))-3-(dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)propyl propanoate 2-naphthalenesulfonate and N-(4-ethoxyphenyl)acetamide  *Aspirin *Phenacetin Drug Combinations Dextropropoxyphene/*analogs & derivatives. Cas Lek Cesk 1983;122(3):83
Midol  83514-22-1 Benzoic acid, 2-(acetyloxy)-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, N-(4-ethoxyphenyl)acetamide and alpha-(1-(methyl(3-phenyl-2-propenyl)amino)ethyl)benzenemethanol hydrochloride  *Aspirin *Caffeine *Phenacetin Drug Combinations Ephedrine/*analogs & derivatives. Arch Intern Med 1982;142(8):1583MIDOL
3-hydroxyphenacetin phosphate  72755-24-9   Phenacetin/*analogs & derivatives. Drug Metab dispos 1980;8(3):188
Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination  64336-56-7   *Aspirin *Caffeine *Oxycodone *Phenacetin Drug Combinations. Kidney Int 1980;17(2):250PERCODAN; ROXIPRIN; PERCODAN-DEMI; OXYCODONE AND ASPIRIN; OXYCODONE AND ASPIRIN (HALF-STRENGTH); CODOXY
N-hydroxyphenacetin glucuronide  69783-19-3 beta-D-Glucopyranuronic acid, 1-((acetyl(4-ethoxyphenyl)amino)oxy)-1-deoxy  Phenacetin/*analogs & derivatives. Pharmacology 1979;19(5):237
Synalgos  79102-58-2 Benzoic acid, 2-(acetyloxy)-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, N-(4-ethoxyphenyl)acetamide and N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine monohydrochloride  *Aspirin *Caffeine *Phenacetin *Promethazine Drug Combinations. Oral Surg 47(6):513;1979
Saridon  8064-93-5   *Caffeine *Phenacetin *Pyridones Antipyrine/*analogs & derivatives Drug Combinations. Br J Dermatol 100(2):183;1979
aspirin, codeine, phenacetin drug combination  52623-91-3   *Aspirin *Codeine *Phenacetin Drug Combinations. Kidney Int 13(1):58;1978
aspirin, caffeine, phenacetin drug combination  0   *Aspirin *Caffeine *Phenacetin Drug Combinations. Kidney Internat 13(1):80;1978
N-hydroxyphenacetin  19315-64-1 N-(4-ethoxyphenyl)-N-hydroxyacetamide  Phenacetin/*analogs & derivatives. Anal Biochem 1980;101(2):462; Chem Biol Interact 8(2):87;1974
Felsol (powder)  8055-46-7   *Antipyrine *Iodine *Phenacetin *Plant Extracts Drug Combinations. Brit Med J 2(805):87;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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