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Phencyclidine

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Definition: A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.     
Pharmacological Action Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hallucinogens
See Also Phencyclidine Abuse; Receptors, Phencyclidine 		Other names GP121; GP 121; Dust, Angel; CL395; CL 395; Serylan; Phencyclidine Hydrochloride; Sernyl; Phencyclidine Hydrobromide; GP-121; CL-395; Angel Dust; 1-(1-Phenylcyclohexyl)piperidine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(1-(2-methylphenyl)(cyclohexyl))-3-piperidinol  0   Phencyclidine/*analogs & derivatives. Arzneimittelforschung. 2010;60(8):492-6
N-(1-phenylcyclohexyl)-2-methoxyethanamine  0   Phencyclidine/*analogs & derivatives Designer Drugs. J Mass Spectrom 2008 Mar;43(3):305-16
N-(1-phenylcyclohexyl)-2-ethoxyethanamine  0   Phencyclidine/*analogs & derivatives Designer Drugs. J Mass Spectrom 2008 Mar;43(3):305-16
2-methoxyphencyclidine  0   Phencyclidine/*analogs & derivatives. Arzneimittelforschung 2006;56(5):346-50
2-hydroxyphencyclidine  0   Phencyclidine/*analogs & derivatives. Arzneimittelforschung. 2005;55(3):172-6
N-(1-(2-benzo(b)thiophenyl)cyclohexyl)piperidin-3-ol  0   Phencyclidine/*analogs & derivatives. Neuroreport 2001 Dec 21;12(18):4165-9
2-phenyl-2-(1-piperidinyl)propane  0   Phencyclidine/*analogs & derivatives. Drug Metab Dispos. 2000 Aug;28(8):905-11
glycyldodecylamide  0   Glycine/*analogs & derivatives Phencyclidine/antagonists & inhibitors Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors. Psychopharmacology (Berl) 1997 Jan;129(1):96-8
1-(1-phenyl-4-hydroxycyclohexyl)-4'-hydroxypiperidine  0   Phencyclidine/*analogs & derivatives. J Anal Toxicol 1997 Sep;21(5):356-62
1-(1-phenyl-2-methylcyclohexyl)piperidine  59397-29-4   Phencyclidine/*analogs & derivatives. J Med Chem 1991;34(8):2615
fourphit  104639-01-2   Phencyclidine/*analogs & derivatives. Biochem Pharmacol 1990;39(11):1825
GK 86  116917-90-9 GK 86  Phencyclidine/*analogs & derivatives. Neurosci Lett 1988;91(2):199
3-nitrophencyclidine  70227-29-1   Phencyclidine/*analogs & derivatives. FEBS Lett 1988;235(1-2):156
3-aminophencyclidine  72242-00-3   Phencyclidine/*analogs & derivatives. FEBS Lett 1988;235(1-2):156
3-phenyl-3-(N-piperidinyl)bicyclo(3.1.0)hexane  114200-20-3   Phencyclidine/*analogs & derivatives. J Med Chem 1988;31(8):1571
1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine  112726-66-6   Phencyclidine/*analogs & derivatives.
Pharma Action Dopamine Agonists 		Eur J Pharmacol 1988;148(3):427
pentalidol  0   *DDT *Lindane *Phencyclidine. Cesk Pediatr 1987;42(10):623
1-(1-phenylcyclohexyl)hexamethyleneimine  2808-81-3 1H-Azepine, hexahydro-1-(1-phenylcyclohexyl)  Phencyclidine/*analogs & derivatives. Drug Metab Dispos 1987;15(5):648
metaphit  96316-00-6   Phencyclidine/*analogs & derivatives. FEBS Lett 1985;181(2):318
1-(1-phenylcyclohexyl)-4-phenyl-4-piperidinol  77179-39-6   Phencyclidine/*analogs & derivatives. J Pharmacol Exp Ther 1984;230(2):383
3-azidophencyclidine  0   *Azides Phencyclidine/*analogs & derivatives. J Neurosci 1984;4(3):627
phencyclidine N-oxide  82413-33-0   Phencyclidine/*analogs & derivatives. Acta Pharm Suec 1983;20(3):181
phenyladamantylpiperidine  72241-99-7   Adamantane/*analogs & derivatives Phencyclidine/*analogs & derivatives. J Med Chem 1983;26(4):479
2-hydroxy-N-(1-phenylcyclohexyl)piperidine  83400-97-9   Phencyclidine/*analogs & derivatives. Drug Metab Dispos 1983;11(1):47
N-(1-phenylcyclohexyl)-1,2,3,4-tetrahydropyridine  85089-73-2 Pyridine, 1,2,3,4-tetrahydro-1-(1-phenylcyclohexyl)  Phencyclidine/*analogs & derivatives. Drug Metab Dispos 1983;11(1):47
5-(1-phenylcyclohexylamine valeraldehyde)  77160-81-7   Phencyclidine/*analogs & derivatives. Drug Metab Dispos 1983;11(1):47
1-(1-phenylcyclohexyl)-3-methylpiperidine  2201-41-4   Phencyclidine/*analogs & derivatives. J Pharmacol Exp Ther 1982;223(3):599
1-(1-phenylcyclohexyl)-4-methylpiperidine  2201-42-5   Phencyclidine/*analogs & derivatives Street Drugs. J Anal Toxicol 1982;6(1):41
3-hydroxyphencyclidine  79787-43-2 Phenol, 3-(1-(1-piperidinyl)cyclohexyl)  Phencyclidine/*analogs & derivatives. Eur J Pharmacol 1981;73(2-3):229
4'-(4-hydroxypiperidino)-4-phenylcyclohexanol  60756-84-5   Phencyclidine/*analogs & derivatives. Drug Metab Dispos 1981;9(3):274
1-(1-phenylcyclohexyl)-4-hydroxypiperidine  60232-85-1   Phencyclidine/*analogs & derivatives. Drug Metab Dispos 1981;9(3):274
4-phenyl-4-piperidinocyclohexanol  60756-83-4   Phencyclidine/*analogs & derivatives. Drug Metab Dispos 1981;9(3):27
5-(N-(1'-phenylcyclohexyl)amino)pentanoic acid  77160-83-9 Pentanoic acid, 5-((1-phenylcyclohexyl)amino)  Phencyclidine/*analogs & derivatives. J Med Chem 1981;24(6):666
1-(1-(2-thienyl)cyclohexyl)pyrrolidine  22912-13-6   Phencyclidine/*analogs & derivatives. J Chromatogr 1980;202(2):309
1-(1-(2-thienyl)cyclohexyl)morpholine  21602-66-4   Phencyclidine/*analogs & derivatives. J Chromatogr 1980;202(2):309
1-(1-phenylcyclohexyl)morpholine  2201-40-3   Phencyclidine/*analogs & derivatives. J Chromatogr 1980;202(2):309
phencyclidine methiodide  7418-82-8   Phencyclidine/*analogs & derivatives. Mol Pharmacol 1980;18(2):179
1-(1-phenylcyclohexyl)pyrrolidine  2201-39-0   Phencyclidine/*analogs & derivatives. Clin Toxicol 14(4):383;1979
1-(1-(2-thienyl)cyclohexyl)piperidine  21500-98-1   Phencyclidine/*analogs & derivatives Street Drugs.
Pharma Action Neuroprotective Agents 		Biochem Biophys Res Commun 88(4):1244;1979; J Chromatogr 117(1):232;1976; Pharmacol Biochem Behav 1980;12(1):67
1-piperidinocyclohexanecarbonitrile  3867-15-0   Phencyclidine/*analogs & derivatives. J Chromatogr 117(1):232;1976; J Pharm Pharmacol 28(9):713;1976; NE J Med 301(8):438;1979

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