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Phenothiazines

More information in Books or onNLM PubMed
Definition: Compounds containing dibenzo-1,4-thiazine. Some of them are neuroactive.     
See Also Antipsychotic Agents
Examples Acepromazine; Azure Stains; Chlorpromazine; Fluphenazine; Mesoridazine; Methotrimeprazine; Methylene Blue; Moricizine; Nonachlazine; Perazine; Perphenazine; Prochlorperazine; Promazine; Promethazine; Thiethylperazine; Thioridazine; Tolonium Chloride; Trifluoperazine; Triflupromazine; Trimeprazine 		Drugs* : PROKETAZINE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-amino-N-(2-(4-(3-(2-trifluoromethylphenothiazin-10-yl)propyl)piperazin-1-yl)-ethyl)acetamide  0   *Acetamides *Phenothiazines. Allergy Asthma Proc. 2011 Sep-Oct;32(5):359-65.
2-amino-N-(2-(4-(3-(2-trifluoromethylphenothiazin-10-yl)propyl)piperazin-1-yl)ethyl)acetamide  0   *Phenothiazines *Piperazines Serotonin 5-HT2 Receptor Antagonists. Eur J Pharmacol. 2011 Nov 16;670(1):195-203.
10-octyl-3-(2-(10-octyl-10H-phenothiazin-3-yl)vinyl)-7-(2-(10-octyl-3-(2-(10-octyl-3-(2-(10-octyl-10H-phenothiazin-7-yl)vinyl)-10H-phenothiazin-7-yl)vinyl)-10H-phenothiazin-7-yl)vinyl)-10H-phenothiazine  0   *Phenothiazines. Talanta 2010 Oct 15;82(5):1943-9
10-octyl-3-(2-(10-octyl-3-(2-(10-octyl-10H-phenothiazin-7-yl)vinyl)-10H-phenothiazin-7-yl)vinyl)-10H-phenothiazine  0   *Phenothiazines. Talanta 2010 Oct 15;82(5):1943-9
7-nitro-1,3-diaza-2-oxophenothiazine  0   *Nitro Compounds *Phenothiazines. J Am Chem Soc. 2009 Apr 1;131(12):4288-93
cyamemazine sulfoxide  0   *Cyclic S-Oxides *Phenothiazines. J Pharm Pharmacol 2008 Nov;60(11):1507-13
monodesmethyl cyememazine  0   *Phenothiazines. J Pharm Pharmacol 2008 Nov;60(11):1507-13
N,N-bis((7-dimethylamino)phenothiazin-5-ium-3-yl)-4,4-ethylenedipiperidine diiodide  0   *Phenothiazines *Piperidines. Org Biomol Chem. 2008 Nov 7;6(21):4026-35
2,3,7,8-tetrachlorophenothiazine  0   *Phenothiazines Tetrachlorodibenzodioxin/*analogs & derivatives. ChemMedChem 2007 Jun;2(6):890-7
RP 12274  0   *Quaternary Ammonium Compounds *Phenothiazines. Chembiochem 2008 Apr 14;9(6):849-52
3,7-bis(N,N-dibutylamino)phenothiazinium bromide  0   *Phenothiazines. Photochem Photobiol Sci 2007 Oct;6(10):1067-75
BN 82204  0   *Phenothiazines. J Neurochem 2006 Aug;98(4):1217-28
2-cyano-10-(3-(dimethylamino)-2-methylpropyl)-5-oxide-phenothiazine  0   *Phenothiazines. Photochem Photobiol Sci 2006 Mar;5(3):336-42
2-cyano-10-(3-(dimethylamino,N-oxide)-2-methylpropyl)-5-oxide-phenothiazine  0   *Phenothiazines. Photochem Photobiol Sci 2006 Mar;5(3):336-42
1,3-diaza-2-oxophenothiazin-3-ylacetic acid  0   *Phenothiazines. Nucleic Acids Res 2004;32(17):5087-95
10-(N,N-dimethylaminopentyl)-2-(trifluoromethyl) phenothiazine  0   *Phenothiazines. Drug Metab Dispos. 2003 Jul;31(7):854-60
2-trifluoromethyl-10-(4-(methylsulfonylamido)butyl)phenothiazine  0   *Phenothiazines *Sulfonamides. Cell Mol Biol Lett 2002;7(2):303
10-(4-(pyrrolidin-1-yl)butyl)phenothiazine  0   *Phenothiazines. J Med Chem 2002 Jun 20;45(13):2741-8
2-amino-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine  0   *Phenothiazines *Piperazines. J Immunol 2001 Sep 1;167(5):2929-35
6-methyl-5-oxo-5H-benzo(a)phenothiazine  0   *Phenothiazines. Int J Antimicrob Agents 2001 Jul;18(1):67-72
5-oxo-5H-benzo(a)phenothiazine  0   *Phenothiazines. Int J Antimicrob Agents 2001 Jul;18(1):67-72
3,7-diaminophenothiazin-5-ium  0   *Phenothiazines. Bioorg Med Chem Lett 2001 Aug 20;11(16):2193-5
OFK 006  0   *Phenothiazines. Biotechnol Appl Biochem 2000 Aug;32 ( Pt 1) 61-7
oxomemazine  3689-50-7   *Cyclic S-Oxides *Phenothiazines. Arch Pharm Res 1994 Dec;17(6):443-51
RP 23618  0   *Phenothiazines Chemokine CCL5/antagonists & inhibitors. Bioorg Med Chem Lett 1998 Apr 7;8(7):771-4
4-bromomethylene violet  0   *Phenothiazines. Photochem Photobiol 1997 Aug;66(2):245-52
benzophenothiazine  28453-74-9   *Phenothiazines. Anticancer Res 1997 Jul-Aug;17(4A):2539-43
10-(4-chlorobutyl)-3-nitrophenothiazine  0   *Phenothiazines. Acta Crystallogr B 1996 Aug 1;52(Pt 4):713-9
1,3,4-trifluoro-2-nitrophenothiazine  0   *Phenothiazines. Acta Crystallogr B 1996 Aug 1;52(Pt 4):713-9
10-(4-chlorobutyl)-1,3,4-trifluoro-2-nitrophenothiazine  0   *Phenothiazines. Acta Crystallogr B 1996 Aug 1;52(Pt 4):713-9
diethazine  60-91-3   *Phenothiazines. Fortschr Med 1983;101(25):1184
metiazinic acid  13993-65-2   *Phenothiazines. Sem Hop Paris 1983;59(46):3197
thiopropazate  84-06-0   *Phenothiazines.
mepazine  60-89-9   *Phenothiazines.
acetophenazine  2751-68-0   *Phenothiazines. TINDAL
fonazine  7456-24-8   *Phenothiazines.
Pharma Action Histamine H1 Antagonists
azure D2  0   *Phenothiazines. Eur J Clin Chem Clin Biochem 1995 Sep;33(9):595-601
RP 60180  0   *Phenothiazines. Prog Neuropsychopharmacol Biol Psychiatry 1995 Jul;19(4):687-97
thioproperazine  316-81-4 10H-Phenothiazine-2-sulfonamide, N,N-dimethyl-10-(3-(4-methyl-1-piperazinyl)propyl)  *Phenothiazines.
profenamine  522-00-9 10H-Phenothiazine-10-ethanamine, N,N-diethyl-alpha-methyl  *Phenothiazines.
Pharma Action Histamine Antagonists ; Adrenergic Antagonists ; Muscarinic Antagonists 		PARSIDOL
pipothiazine  39860-99-6 10H-Phenothiazine-2-sulfonamide,10-(3-(4-(2-hydroxyethyl)-1-piperidinyl)propyl)-N,N-dimethyl  *Phenothiazines.
pipothiazine palmitate  37517-26-3 Hexadecanoic acid, 2-(1-(3-(2-((dimethylamino)sulfonyl)-10H-phenothiazin-10-yl)propyl)-4-piperidinyl)ethyl ester  *Phenothiazines.
butaperazine  653-03-2 1-Butanone, 1-(10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazin-2-yl)  *Phenothiazines.
propiomazine  362-29-8 1-Propanone, 1-(10-(2-(dimethylamino)propyl)-10H-phenothiazin-2-yl)  *Phenothiazines. LARGON
periciazine  2622-26-6   *Phenothiazines.
2-(10H-phenothiazin-2-yloxy)-N,N-dimethylethanamine  137966-38-2   *Phenothiazines. J Med Chem 1992 Feb 21;35(4):716-24
piperacetazine  3819-00-9 1-(10-(3-(4-(2-hydroxyethyl)-1-piperidinyl)propyl)-10H-phenothiazin-2-yl)ethanone  *Phenothiazines. QUIDE
10-N-methylcarbamoyl-3,7-dimethylamino-10H-phenothiazine  0   *Phenothiazines.
methylene violet  2516-05-4   *Phenothiazines. Analyst 1989;114(4):513
L 156903  116740-51-3   *Oligopeptides *Phenothiazines. Brain Res 1988;457(2):212
sulforidazine-5-sulfoxide  106939-06-4   *Phenothiazines. J Chromatogr 1987;423:227
duoperone  62030-88-0   *Phenothiazines. J Chromatogr 1987;419:452
4-bromo-2,7-dimethoxy-3H-phenothiazin-3-one  93211-49-5   *Phenothiazines.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Lipoxygenase Inhibitors 		Eur J Pharmacol 1987;139(1):11
LG 30435  101396-42-3   *Phenothiazines. Eur J Pharmacol 1986;126(1-2):81
10-(3-(3-hydroxypyrrolidinyl)propyl)-2-trifluoromethylphenothiazine  62848-18-4   *Phenothiazines *Pyrrolidines. J Chromatogr 1986;377:436
fenoverine  37561-27-6   *Phenothiazines.
Pharma Action Parasympatholytics 		Pharmatherapeutica 1986;4(7):422
ethacizine  33414-33-4   *Phenothiazines.
Pharma Action Anti-Arrhythmia Agents ; Psychotropic Drugs 		Farmakol Toksikol 1985;48(4):112
phenothiazine-calmodulin complex  0   *Calmodulin *Phenothiazines. Biochim Biophys Acta 1985;845(3):533
N-methylphenothiazine  1207-72-3   *Phenothiazines. Pharmazie 1985;40(3):202
methdilazine  1982-37-2   *Phenothiazines. Neuropharmacology 1985;24(1):1TACARYL; METHDILAZINE HYDROCHLORIDE
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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