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Phosphatidic Acids

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Definition: Fatty acid derivatives of glycerophosphates. They are composed of glycerol bound in ester linkage with 1 mole of phosphoric acid at the terminal 3-hydroxyl group and with 2 moles of fatty acids at the other two hydroxyl groups.     
Examples Glycerophospholipids; Lysophospholipids 		Other names Phosphatidate, Ammonium; Acids, Phosphatidic; Acid, Phosphatidic; Phosphatidic Acid; Diacylglycerophosphates; Ammonium Phosphatidate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-carba-cyclic phosphatidic acid  0   *Phosphatidic Acids. Biochim Biophys Acta. 2011 Apr;1811(4):271-7
3-carba cyclic-phosphatidic acid  0   *Phosphatidic Acids. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7525-8
cyclic phosphatidic acid 16:0  0   *Heterocyclic Compounds, 1-Ring *Phosphatidic Acids. Biochem Biophys Res Commun 2011 Jan 7;404(1):109-14
3-O-carba-oleoyl-cyclic phosphatidic acid  0   *Phosphatidic Acids. Eur J Pharmacol. 2006 Aug 14;543(1-3):27-31
1-palmitoyl-2-oleoyl-phosphatidyl-uridine  0   *Phosphatidic Acids Uridine/*analogs & derivatives. Biophys J 2006 Feb 15;90(4):1260-9
1-oleoyl-2-O-methylglycerophosphothioate  0   *Organothiophosphorus Compounds *Phosphatidic Acids. J Med Chem 2003 Dec 18;46(26):5575-8
dilauroylphosphatidic acid  0   *Phosphatidic Acids Phospholipids. Biophys J. 2002 Dec;83(6):3507-12
1-oleoyl-2-O-methyl-rac-glycerophosphothionate  0   *Phosphatidic Acids *Thiophosphoric Acid Esters. J Biol Chem 2003 Apr 4;278(14):11962-9
1-O-oleoyl-2-O-(12-(N-(azido-2,3,5,6-tetrafluorobenzoyl))aminododecanoyl)-sn-glycero-3-phosphate  0   *Azides *Phosphatidic Acids. J Med Chem 2002 Apr 1;45(8):1678-85
1-O-(12-(N-(4-azido-2,3,5,6-tetrafluorobenzoyl))aminododecanoyl)-2-O-oleoyl-sn-glycero-3-phosphate  0   *Azides *Phosphatidic Acids. J Med Chem 2002 Apr 1;45(8):1678-85
1-O-palmitoyl-2-O-(12-(N-(4-azido-2,3,5,6-tetrafluorobenzoyl))aminododecanoyl)-sn-glycero-3-phosphate  0   *Azides *Phosphatidic Acids. J Med Chem 2002 Apr 1;45(8):1678-85
docosahexaenoylnoylphosphatidate  0   *Docosahexaenoic Acids *Phosphatidic Acids. Neurochem Res 2000 May;25(5):693-703
alpha-(N-acetylneuraminyl)phosphatidyloctanediol  0   *Phosphatidic Acids *Sialic Acids. J Med Chem 1997 Oct 10;40(21):3332-5
methyl 2,3,4-tri-O-acetyl-6-(1'-O-stearoyl-2'-O-acetyl-DL-glycero-3'-phosphoryl)-alpha-D-glucopyranoside ammonium salt  0   *Glucosides *Phosphatidic Acids. Int J Biochem Cell Biol 1997 May;29(5):767-74
1,2-dipalmitoyl-sn-glycero-3-phosphatidylethanol  0   *Phosphatidic Acids. Biophys J 1996 Sep;71(3):1440-9
1-palmitoyl-2-oleoyl-glycero-3-phosphatidic acid  0   *Phosphatidic Acids. Anal Biochem 1996 Aug 15;240(1):37-47
phosphatidylpropanol  0   *Phosphatidic Acids. Biochem J 1996 Feb 15;314(Pt 1):129-38
GlyT-(GlyA-GlyT)9  0   *Phosphatidic Acids Thymine/*analogs & derivatives. Int J Biol Macromol 1995 Oct;17(5):239-46
(GlyA-dT)10  0   *Phosphatidic Acids Thymidine/*analogs & derivatives. Int J Biol Macromol 1995 Oct;17(5):239-46
dodecaglycerol-adenine  0   *Phosphatidic Acids Adenine/*analogs & derivatives. Int J Biol Macromol 1995 Oct;17(5):239-46
dodecaglycerol-thymine  0   *Phosphatidic Acids Thymine/*analogs & derivatives. Int J Biol Macromol 1995 Oct;17(5):239-46
1-(2-nitrophenyl)ethyl-phosphatidic acid  0   *Phosphatidic Acids. J Biol Chem 1995 Dec 15;270(50):29656-9
1,2-didecanoyl-3-phosphatidic acid  80164-20-1   *Phosphatidic Acids. J Biochem (Tokyo) 1994 Feb;115(2):238-44
1-oleoyl-2-((N-(7-(nitro)-2,1,3-benzoxadiazol-4-yl)amino)hexanoyl)glycero-3-phosphate  0   *Phosphatidic Acids 4-Chloro-7-nitrobenzofurazan/*analogs & derivatives. Biochemistry 1994 Apr 19;33(15):4517-20
N(6)-(7-nitro-2,1,3-benzoxadiazol-4-yl)aminohexanoyl-1-phosphatidic acid  0   *Phosphatidic Acids 4-Chloro-7-nitrobenzofurazan/*analogs & derivatives. J Biol Chem 1994 Jan 21;269(3):1763-9
dioctanoylphosphatidic acid  102731-57-7   *Phosphatidic Acids. J Biol Chem 1993 Dec 5;268(34):25302-10
phosphatidic acid-beta-lactoglobulin  0   *Lactoglobulins *Lipoproteins *Phosphatidic Acids. Nature 1993 Sep 16;365(6443):213-4
triethylammonium 1,2-di-O-hexadecyl-glycero-3-H-phosphonate  129983-81-9   *Quaternary Ammonium Compounds *Phosphatidic Acids. Nucleic Acids Res 1990;18(13):3777
fluorescein phosphatidylethanolamine thiocarbamide  0   *Phosphatidic Acids. Biochemistry 1990;29(1):37
dicaproylphosphatidic acid  97525-39-8   *Phosphatidic Acids. J Biol Chem 1989;265(1):166
1-palmitoyl-2-((2-(4-(6-phenyl-1,3,5-hexatrienyl)phenyl)ethyl)carbonyl)-3-phosphatidic acid  124345-22-8   *Phosphatidic Acids. Biophys J 1989;56(4):723
1-stearoyl-2-arachidonoylphosphatidic acid  119904-30-2   *Phosphatidic Acids. J Cell Physiol 1989;139(3):558
1-palmitoyl-2-(6-(pyren-1-yl)hexanoyl)-sn-glycero-3-phosphatidic acid  121496-64-8   *Pyrenes *Phosphatidic Acids. Biochemistry 1988;27(9):3433
fluorescein phosphatidylethanolthiocarbamide  0   *Fluoresceins *Phosphatidic Acids. Biochim Biophys Acta 1988;939(2):289
1,2-dipalmitoyl-sn-glycerol 3-((((4-azido-2-nitrophenyl)amino)ethyl)phosphate)  110457-62-0   *Azides *Phosphatidic Acids. Biochemistry 1987;26(22):7107
1,2-dipalmitoyl glycero-3-thiophosphate  106249-23-4   *Phosphatidic Acids. Chem Phys Lipids 1986;41(2):173
1,2-dipentadecylmethylidene phosphatidic acid  76749-50-3 1,3-Dioxolane-4-methanol, 2,2-dipentadecyl-, (R)  *Phosphatidic Acids. Biochim Biophys Acta 1985;813(2):221
1,2-dilauroylphosphatidic acid  79806-85-2   *Phosphatidic Acids. Biochim Biophys Acta 1984;774(2):227
dioleoylphosphatidic acid  14268-17-8   *Phosphatidic Acids. Biochem Biophys Res Commun 1983;111(2):675
dipalmitoylphosphatidic acid  19698-29-4   *Phosphatidic Acids. Mol Pharmacol 1981;19(3):432
active pressor principle  0   *Phosphatidic Acids. Am J Obstet Gynecol 1980;138(7 pt 1):741
semilysobisphosphatidic acid  0   *Phosphatidic Acids. Biochim Biophys Acta 574(3):461;1979
bisphosphatidic acid  0   *Phosphatidic Acids. Biochim Biophys Acta 574(3):461;1979
1,2-(ditetradecyl)phosphatidic acid  78529-88-1 1-Propanol, 2,3-bis(tetradecyloxy)-, dihydrogen phosphate, disodium salt, (R)  *Phosphatidic Acids. Biochim Biophys Acta 555(3):409;1979
darmstoff  0   *Phosphatidic Acids. J Med Chem 21(3):245;1978
YN emulsifier  55965-13-4   *Phosphatidic Acids *Triglycerides Emulsions. Food Cosmet Toxicol 13(1):23;1975; Food Cosmet Toxicol 15(1):1;1977
2,3-di-O-phytanyl-1-glycerophosphate  0   *Phosphatidic Acids.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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