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Plasminogen

More information in Books or onNLM PubMed
Definition: Precursor of plasmin (FIBRINOLYSIN). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.  an enzyme precursor & fibrinolytic agent; /antag: do not confuse with PLASMINOGEN INACTIVATORS which modulate PLASMINOGEN ACTIVATORS, not PLASMINOGEN   
Pharmacological Action Fibrinolytic Agents
Examples Angiostatins 		Other names Profibrinolysin; Plasminogen, Glutamyl; Glutamic Acid 1 Plasminogen; Glu Plasminogen; 1-Plasminogen, Glutamic Acid; Glutamyl Plasminogen; Glutamic Acid 1-Plasminogen; Glu-Plasminogen
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
recombinant plasminogen kringle5, human  0   *Plasminogen Recombinant Proteins. Nuklearmedizin. 2011;50(6):234-9
BB-10153  0   *Plasminogen. J Thromb Haemost 2005 Jan;3(1):146-53
plasminogen kringle 5  0   *Peptide Fragments *Plasminogen. Diabetologia 2004 Jan;47(1);124-31
recombinant kringle 1-3 (rKI-3) of human plasminogen  0   *Peptide Fragments *Plasminogen. Clin Cancer Res 1999 Nov;5(11):3689-94
PLGLB1 protein, human  0   *Plasminogen Peptides. Eur J Biochem 1999 Feb;259(3):618-25
plasminogen-related protein A, human  0   *Plasminogen Peptides. Eur J Biochem 1999 Feb;259(3):618-25
microplasminogen protein, human  0   *Peptide Fragments *Plasminogen. Ciba Found Symp 1997;212:66-83
plasminogen (S741C-fluorescein)  0   *Fluoresceins *Plasminogen. J Biol Chem 1997 Jan 24;272(4):2176-82
lysyl(78) plasminogen  0   *Plasminogen. Haemostasis 1996 Jul-Aug;26(4):220-7
plasminogen Maywood I  0   *Plasminogen. Thromb Haemost 1991 Nov;66(5):575-80
streptokinase-plasminogen complex  0   *Plasminogen *Streptokinase Drug Combinations. Behring Inst Mitt 1986;(79):263
miniplasminogen  0   *Peptide Fragments *Plasminogen. Thromb Res 1984;36(4):345
Tochigi II plasminogen  0   *Plasminogen Peptide Fragments. J Biochem (Tokyo) 1984;96(2):277
BRL 33575  94587-92-5 BRL 33575  *Plasminogen *Streptokinase. Thromb Haemost 1984;51(3):403
plasminogen Chicago III  0   *Plasminogen. Thromb Haemost 1982;48(2):146
plasminogen-valine  0   *Peptide Fragments *Plasminogen. Biochem Biophys Res Commun 1981;102(1):46; J Biol Chem 1980;255(11):5329
lysyl-plasminogen  0   *Peptide Fragments *Plasminogen. Angiology 30(1):1;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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