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Plasminogen Activators

More information in Books or onNLM PubMed
Definition: A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.  /antag: consider also PLASMINOGEN INACTIVATORS   
Examples Anistreplase 		Other names Uterine Tissue Plasminogen Activator; Uterine-Tissue Plasminogen Activator; Plasminogen Activator; Extrinsic Plasminogen Activators
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
longistatin protein, Haemaphysalis longicornis  0   *Calcium-Binding Proteins *Salivary Proteins and Peptides Plasminogen Activators EF Hand Motifs. Int J Parasitol 2010 May;40(6):721-9
1-benzyl-3-pentyl-2-(6-(1H-tetrazol-5-ylmethoxy)naphthalen-2-yl)-1H-indole  0   *Indoles *Tetrazoles Plasminogen Activators/antagonists & inhibitors. Mol Pharmacol 2007 Oct;72(4):897-906
plasminogen activator, Agkistrodon blomhoffii Ussurensis  EC 3.4.21.-   *Carboxylic Ester Hydrolases *Plasminogen Activators. Biochem Biophys Res Commun 2006 Oct 6;348(4):1279-87
monteplase  0   *Plasminogen Activators. Am Heart J 2002 Oct;14(4):E5
cyclo(19,31)-urokinase-type plasminogen activator (19-31)  0   *Peptide Fragments *Urokinase-Type Plasminogen Activator Peptides, Cyclic Plasminogen Activators/antagonists & inhibitors. Biol Chem 2001 Aug;382(8):1197-205
PauB protein, Streptococcus uberis  0   *Bacterial Proteins *Plasminogen Activators. J Bacteriol 2002 Jan;184(1):119-25
glycyl-histidyl-arginyl-prolyl-single-chain urokinase-type plasminogen activator (144-411)  0   *Peptide Fragments *Plasminogen Activators. Biochim Biophys Acta 2001 Apr 7;1546(2):399-405
Silteplase  131081-40-8   *Plasminogen Activators. Neurol Res 1996 Aug;18(4):342-4
K1K2Pu  0   *Plasminogen Activators Recombinant Fusion Proteins. Coron Artery Dis 1993 Oct;4(10):929-33
Pla protease, Yersinia pestis  EC 3.4.21.-   *Bacterial Proteins *Plasminogen Activators. Science 1992 Nov 6;258(5084):1004-7
salivary plasminogen activator alpha 1, Desmodus rotundus  0   *Plasminogen Activators Recombinant Proteins.
Pharma Action Fibrinolytic Agents 		Circulation 1991;84(1):244
Hybrid-B  0   *Plasminogen Activators Recombinant Proteins. Circulation 1991;83(4):1429
omptin outer membrane protease  EC 3.4.21.87   *Serine Endopeptidases Plasminogen Activators. J Bacteriol 1988;170(12):5625
SK potentiator  0   *Plasminogen Activators Drug Synergism. Thromb Res 13(3):325;1978
plasminogen proactivator  0   *Enzyme Precursors *Plasminogen Activators. Arch Jpn Chir 46(3):258;1977; J Physiol Soc Jpn 36(8-9):368;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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