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Platelet-Derived Growth Factor

More information in Books or onNLM PubMed
Definition: Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.  DF: PDGF   
See Also Receptors, Platelet-Derived Growth Factor
Examples Proto-Oncogene Proteins c-sis 		Other names Growth Factor, Platelet-Derived; Factor, Platelet-Derived Growth; Platelet Derived Growth Factor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PVF-1 protein, C. elegans  0   *Platelet-Derived Growth Factor *Caenorhabditis elegans Proteins. FASEB J. 2006 Feb;20(2):227-33
Scdgfb protein, rat  0   *Lymphokines *Platelet-Derived Growth Factor.
Pdgfd protein, mouse  0   *Lymphokines *Platelet-Derived Growth Factor.
RP 1776  0   *Peptides, Cyclic *Depsipeptides Platelet-Derived Growth Factor/antagonists & inhibitors. J Antibiot (Tokyo) 2001 May;54(5):405-14
PDGFD protein, human  0   *Lymphokines *Platelet-Derived Growth Factor. Circulation 2001 May 8;103(18):2242-7
GFB 111  0   *Peptides, Cyclic Platelet-Derived Growth Factor. Nat Biotechnol 2000 Oct;18(10):1065-70
platelet-derived growth factor C  0   *Lymphokines *Platelet-Derived Growth Factor. Nat Cell Biol 2000 May;2(5):302-9
6,7-dimethoxy-2-phenylquinoxaline  0   *Tyrphostins Platelet-Derived Growth Factor/antagonists & inhibitors. Arterioscler Thromb Vasc Biol 2000 Mar;20(3):667-76
CEV14-PDGFRbeta fusion protein, human  0   *Platelet-Derived Growth Factor *Oncogene Proteins, Fusion. Blood 1997 Dec 1;90(11):4271-7
SCH 13835  150519-34-9   *Phthalimides *Sulfonamides Platelet-Derived Growth Factor/antagonists & inhibitors. J Chromatogr A 1997 Feb 21;762(1-2):159-65
PDAP1 protein, human  0   *Intercellular Signaling Peptides and Proteins Platelet-Derived Growth Factor. J Neurochem 1996 May;66(5):2213-6
platelet-derived growth factor AB  0   *Platelet-Derived Growth Factor Recombinant Proteins. Exp Cell Res 1995 Sep;220(1):29-35
platelet-derived growth factor A (194-211)  0   *Peptide Fragments *Platelet-Derived Growth Factor. Peptides 1994 Jan;15(1):133-7
platelet-derived growth factor A  0   *Platelet-Derived Growth Factor. Genomics 1992 Jun;13(2):257-63

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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