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Polyglutamic Acid

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Definition: A peptide that is a homopolymer of glutamic acid.      Other names Polyglutamate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
poly(N-isopropylacrylamide-co-N-hydroxymethylacrylamide)-b-poly(glutamic acid)  0   Polyglutamic Acid/*analogs & derivatives. Chemistry. 2012 Feb 20;18(8):2297-304
poly (L-glutamic acid) grafted polyethylenimine  0   *Polyethyleneimine *Polyglutamic Acid. Pharm Res. 2011 Apr;28(4):812-26
NC 6004  0   *Organoplatinum Compounds Polyglutamic Acid/*analogs & derivatives. Br J Cancer 2011 Feb 15;104(4):593-8
poly(gamma-azidopropylglutamate)  0   Polyglutamic Acid/*analogs & derivatives. Biomacromolecules 2010 Jun 14;11(6):1585-92
poly(gamma-chloropropylglutamate)  0   Polyglutamic Acid/*analogs & derivatives. Biomacromolecules 2010 Jun 14;11(6):1585-92
poly-1-glutamic acid-gemcitabine  0   Deoxycytidine/*analogs & derivatives Polyglutamic Acid/*analogs & derivatives. Int J Pharm 2010 May 31;391(1-2):212-20
poly(gamma-benzyl glutamate)-b-hyaluronan  0   Hyaluronic Acid/*analogs & derivatives Polyglutamic Acid/*analogs & derivatives.
alpha-methoxy-poly(ethylene glycol)-b-poly(gamma-benzyl-L-glutamate)2  0   *Polyethylene Glycols *Polyglutamic Acid. J Nanosci Nanotechnol. 2009 Aug;9(8):4805-11
dextran-block-poly(-benzyl L-glutamate) copolymer  0   *Dextrans Polyglutamic Acid/*analogs & derivatives. Angew Chem Int Ed Engl. 2009;48(14):2572-5
poly(gamma-benzyl glutamate)-beta-cyclodextrin  0   *beta-Cyclodextrins Polyglutamic Acid/*analogs & derivatives. J Mol Recognit 2008 May-Jun;21(3):169-78
vanadyl-poly (gamma-glutamic acid)  0   *Polyglutamic Acid *Vanadates. J Biomater Appl 2008 Mar;22(5):449-64
polyglutamate camptothecin  0   Camptothecin/*analogs & derivatives Polyglutamic Acid/*analogs & derivatives. Clin Cancer Res 2007 Oct 1;13(19):5855-61
poly(glutamic acid)-DTPA-gadolinium-NIR813  0   *Indoles *Polyglutamic Acid. Invest Radiol 2007 AUG;42(8):569-78
technetium 99m polyglutamate 3-aminoethyl estradiol  0   *Polyglutamic Acid *Organotechnetium Compounds Estrone/*analogs & derivatives. Eur J Nucl Med Mol Imaging 2007 Mar;34(3):354-62
benzylamidated poly(gamma-glutamic acid)  0   *Polyglutamic Acid. Biomacromolecules 2007 May;8(5):1624-32
polyethylenimine-poly(gamma-benzylglutamate)  0   Polyethyleneimine/*analogs & derivatives Polyglutamic Acid/*analogs & derivatives. Chemistry 2006 May 24;12(16):4305-12
poly(gamma-glutamic acid)  0   Polyglutamic Acid/*analogs & derivatives. Chem Rec 2005;5(6):352-66
poly(gamma-benzylglutamate)-b-poly(dimethyl siloxane)-b-poly(gamma-benzylglutamate)  0   *Siloxanes Polyglutamic Acid/*analogs & derivatives. Biomacromolecules 2006 Feb;7(2):618-26
poly(ethylene glycol)-b-poly(lactide)-b-poly(glutamic acid)  0   *Polyethylene Glycols Polyglutamic Acid/*analogs & derivatives. Biomacromolecules 2006 Feb;7(2):590-6
paclitaxel poliglumex  0   Polyglutamic Acid/*analogs & derivatives Paclitaxel/*analogs & derivatives. Clin Cancer Res 2005 Nov 1;11(21):7834-40
poly(gamma-glutamic acid)-graft-phenylalanine ethylester copolymer  0   *Polyglutamic Acid Phenylalanine/*analogs & derivatives. Biomacromolecules 2006 Jan;7(1):297-303
PEG-PEI-PBLG  0   *Polyethylene Glycols *Polyglutamic Acid. Biomaterials. 2005 Jul;26(20):4209-17
poly(gamma-benzyl-l-glutamic acid)-b-poly(ethylene oxide)-b-poly(epsilon-caprolactone)  0   *Lactones *Polyethylenes Polyglutamic Acid/*analogs & derivatives. Biomaterials. 2004 Aug;25(17):3553-8
poly(glutamic acid)sulfonate  0   Polyglutamic Acid/*analogs & derivatives. Bioconjug Chem 2002 Jan-Feb;13(1):23-8
tetrahydrofolate polyglutamate  0   Polyglutamic Acid/*analogs & derivatives Tetrahydrofolates. Biochemistry 2000 Apr 18;39(15):4259-66
tubulin polyglutamylase  EC 6.3.2.-   *Peptide Synthases Polyglutamic Acid Tubulin. Biochemistry 1998 Jun 9;37(23):8395-404
poly(glutamic acid-leucine)  0   *Polyglutamic Acid Leucine/*analogs & derivatives. J Pept Res 1997 Mar;49(3):269-721
poly(gamma-benzylglutamate)poly(ethylene oxide)  0   *Polyethylene Glycols Polyglutamic Acid/*analogs & derivatives. J Biomed Mater Res 1996 Nov;32(3):425-32
gelatin-polyglutamic acid glue  0   *Gelatin *Polyglutamic Acid Drug Combinations Hydrogels. J Biomed Mater Res 1996 Jun;31(2):157-66
inerpan  0   Leucine/*analogs & derivatives Polyglutamic Acid/*analogs & derivatives Occlusive Dressings. Burns 1992 Oct;18(5):419-22
poly(spiropyran-glutamate)  130037-82-0   *Benzopyrans Polyglutamic Acid/*analogs & derivatives. Photochem Photobiol 1992 Jan;55(1):1-7
poly(gamma-benzylglutamate)-poly(ethylene oxide)-poly(gamma-benzylglutamate) copolymer  109179-89-7   *Polyethylenes Polyglutamic Acid/*analogs & derivatives. J Biomed Mater Res 1990;24(10):1369
teichuronopeptide  0   *Glucuronates Polyglutamic Acid/*analogs & derivatives Polysaccharides, Bacterial. Biochem J 1990;270(2):363
polydimethylsiloxane-poly(gamma-benzylglutamate)copolymer  0   *Dimethylpolysiloxanes Polyglutamic Acid/*analogs & derivatives. Biomaterials 1988;9(4):349
poly(methyl methacrylate)-poly(gamma-benzylglutamate) copolymer  32799-40-9   *Methylmethacrylates Polyglutamic Acid/*analogs & derivatives. Biomaterials 1986;7(5):386
polystyrene-poly(gamma-benzylglutamate) copolymer  64091-22-1   *Polystyrenes Polyglutamic Acid/*analogs & derivatives. Biomaterials 1986;7(5):386
A-B-A triblock copolymer  78967-00-7   *Butadienes Polyglutamic Acid/*analogs & derivatives. J Biomed Mater Res 1985;19(9):1135
copoly(gamma-benzylglutamate-gamma-hydroxyethylglutamine)  0   Polyglutamic Acid/*analogs & derivatives. J Biomed Mater Res 1985;19(7):863
poly(lysly-glutamine)  92352-83-5 L-Glutamine, N2-L-lysyl-, (16alpha)  Polyglutamic Acid/*analogs & derivatives Polylysine/*analogs & derivatives. Int J Pept Protein Res 1984;24(1):48
3-(2-pyridyldithio)propionyl-polyglutamic acid  98167-04-5   *Pyridines Polyglutamic Acid/*analogs & derivatives Drug Carriers. JNCI 1984;73(3):721
glutamic acid-5-ethyl glutamate copolymer  29323-51-1   Polyglutamic Acid/*analogs & derivatives Drug Implants. Biopolymers 1983;22(1):547
cis-diammineplatinum(II)-polyglutamic acid complex  0   Cisplatin/*analogs & derivatives Polyglutamic Acid/*analogs & derivatives. Antimicrob Agents Chemother 1984;25(2):286
poly(glutamic acid-alanine)  75734-91-7   *Polyglutamic Acid Alanine/*analogs & derivatives. Immunol Commun 1982;11(3):165
poly(glutamic acid-lysine)  27456-64-0   Polyglutamic Acid/*analogs & derivatives Polylysine/*analogs & derivatives. Eur J Immunol 1981;11(3):241
poly-gamma-methylglutamate  25086-16-2 L-Glutamic acid, 5-methyl ester, homopolymer  Polyglutamic Acid/*analogs & derivatives. Nature 1981;291(5814):401
4-aminobenzoyl-poly-gamma-glutamate  76567-21-0 L-Glutamic acid, N-(4-aminobenzoyl)-, homopolymer  Polyglutamic Acid/*analogs & derivatives. Anal Biochem 1980;107(1):109
gamma-benzylglutamate-alanine copolymer  37475-30-2 L-Glutamic acid, 5-(phenylmethyl) ester, polymer with L-alanine  Alanine/*analogs & derivatives Polyglutamic Acid/*analogs & derivatives. Biomater Med Devices Artif Organs 1980;8(2):95
copolymer Glu(60)Phe(40)  26655-91-4 L-Glutamic acid, polymer with L-phenylalanine  *Polyglutamic Acid Phenylalanine/*analogs & derivatives. Immunol Commun 1979;8(5-6)531
methotrexate polyglutamate  82334-40-5 Poly(imino(1-carboxy-4-oxo-1,4-butanediyl)), alpha-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-omega-hydroxy-, (S)  Methotrexate/*analogs & derivatives Polyglutamic Acid/*analogs & derivatives. Cancer Res 37(2):408;1977; Cancer Res 39(3):735;1979
poly-gamma-benzyl-L-glutamate  25014-27-1   Polyglutamic Acid/*analogs & derivatives.
Pharma Action Contrast Media 		Biopolymers 14(6):1223;1975; Biopolymers 15(5):929;1976; J Am Chem Soc 98(11):3094;1976; Science 176(041):1335;1972; Trans Am Soc Artif Intern Organs 1979;25:159

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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