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Porifera

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Definition: The phylum of sponges which are sessile, suspension-feeding, multicellular animals that utilize flagellated cells called choanocytes to circulate water. Most are hermaphroditic. They are probably an early evolutionary side branch that gave rise to no other group of animals. Except for about 150 freshwater species, sponges are marine animals. They are a source of ALKALOIDS; STEROLS; and other complex molecules useful in medicine and biological research.     
Examples Agelas; Axinella; Callyspongia; Crambe Sponge; Dysidea; Geodia; Haliclona; Petrosia; Plakortis; Suberites; Theonella; Xestospongia 		Other names Sponges (Zoology); Demospongiae; Sponge; Poriferas; Sponges; Sponge (Zoology)
 
SubstanceCAS Registry & nameCategoriesSource
mucus-like protein, Geodia cydonium  0   *Extracellular Matrix Proteins Porifera. J Mol Evol 2001 Oct-Nov;53(4-5):402-15
bhp2 protein, Geodia cydonium  0   *Proto-Oncogene Proteins c-bcl-2 Porifera. Cell Death Differ 2001 Sep;8(9):887-98
PNG 41  150165-20-1 PNG 41  *Biological Factors Muscle Relaxation Porifera. Proc West Pharmacol Soc 1993;36:317-22
lectin-1, Geodia cydonium  0   *Galectins Porifera. Glycobiology 1993 Apr;3(2):179-84
lectin I, Axinella polypoides  149222-82-2   *Lectins Porifera. Biochim Biophys Acta 1992 Sep 4;1159(1):1-8
Pellina semitubulosa lectin  0   *Lectins Porifera. Biochimie 1992 Jun;74(6):527-37
halistanol trisulfate  103065-20-9   *Sterols Porifera. Biochem Biophys Res Commun 1992;182(1):115
oxysceptrin  117417-62-6 1H-Pyrrole-2-carboxamide, N,N'-((3-(2-amino-4,5-dihydro-5-oxo-1H-imidazol-4-yl)-4-(2-amino-1H-imidazol-4-yl)-1,2-cyclobutanediyl)bis(methylene))bis(4-bromo-, (1R-(1alpha,2beta,3alpha,4beta))  *Alkaloids Porifera. Experientia 1991;47(3):301
purealidin A  134850-51-4 Benzenepropanamide, N-(2-(2-amino-1H-imidazol-4-yl)ethyl)-4-(3-aminopropoxy)-3,5-dibromo-alpha-(hydroxyimino)  *Alkaloids Cytotoxins Porifera. Experientia 1991;47(3):299
avarol monoacetate  122143-92-4   *Sesquiterpenes Porifera. J Nat Prod 1989;52(3):646
theonellapeptolide Ie  109767-22-8 Theonellapeptolide Id, 4-(N-methyl-beta-alanine)  *Peptides Porifera. Chem Pharm Bull (Tokyo) 1987;35(5):2129
N-formyl-1,2-dihydrorenierone  97581-08-3   *Isoquinolines Porifera. Chem Pharm Bull (Tokyo) 1986;34(10):4056
7-methoxy-1,6-dimethyl-5,8-dihydroisoquinoline-5,8-dione  79664-58-7   *Isoquinolines Porifera. Chem Pharm Bull (Tokyo) 1986; 34(10):4056
renierone  73777-65-8   *Isoquinolines Porifera. Chem Pharm Bull (Tokyo) 1986;34(10):4056
hymenidin  107019-95-4   *Pyrroles Porifera. Experientia 1986;42(10):1176
purealin  100101-28-8 1-Oxa-2-azaspiro(4.5)deca-2,6,8-triene-3-carboxamide, N-(3-(4-(3-((2-(2-amino-1H-imidazol-4-yl)ethyl)amino)-2-(hydroxyimino)-3-oxopropyl)-2,6-dibromophenoxy)propyl)-7,9-dibromo-10-hydroxy-8-methoxy-, (5R-trans)  *Bromobenzenes Porifera. J Biol Chem 1986;261(29):13861
ficulinic acid B  102791-31-1   *Keto Acids Porifera. J Nat Prod 1986;49(2):307
ficulinic acid A  102791-30-0   *Keto Acids Porifera. J Nat Prod 1986;49(2):307
17-tetracosenal  103424-62-0   *Aldehydes Porifera. Chem Phys Lipids 1986;39(4):365
hyrtial  97889-56-0 D-Homoandrost-16-ene-17-carboxaldehyde, 12-(acetyloxy)-4,4,8-trimethyl-, (5alpha,12beta)  *Terpenes Porifera. Experientia 1985;41(5):690
latrunculin B  76343-94-7 2-Thiazolidinone, 4-(15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo(11.3.1)heptadeca-4,8-dien-15-yl)-, (1R*,4Z,8Z,10S*,13R*,15R*(R*))-(+)  *Bicyclo Compounds, Heterocyclic *Thiazolidines Marine Toxins Porifera. Science 1983;219(4584):493
latrunculin A  76343-93-6 2-Thiazolidinone, 4-(17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo(13.3.1)nonadeca-4,8,10-trien-17-yl)-, (1R*,4Z,8E,10Z,12S*,15R*,17R*(R*))-(+)  *Bicyclo Compounds, Heterocyclic *Thiazolidines Marine Toxins Porifera. Science 1983;219(4584):493
spongiatriol  71302-27-7 18-Nor-16-oxaandrosta-13(17),14-dien-2-one, 3-hydroxy-4,8-bis(hydroxymethyl)-4-methyl-, (3alpha,4beta,5alpha)  *Diterpenes Marine Toxins Porifera. Aust J Exp Biol Med Sci 1982;60(3):253
suberitine protein, Suberites domuncula  0   *Proteins Marine Toxins Neurotoxins Porifera. Experientia 1981;37(8):801
aplysinopsin  63153-56-0 4-Imidazolidinone, 2-imino-5-(1H-indol-3-ylmethylene)-1,3-dimethyl  Tryptophan/*analogs & derivatives Porifera. Lloydia 40(5):479;1977
cell aggregation factors  0   *Cell Adhesion Molecules Cell Adhesion Cell Aggregation/drug effects Porifera. Biochemistry 1980;19(5):1038; Cell Membranes Tumor Cell Behavior, W3 SY5177:176;1975; Exp Cell Res 80(1):95;1973; J Biol Chem 252(11):3836;1977

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