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Pregnenes

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Definition: Unsaturated derivatives of PREGNANES.  do not confuse with PREGNANES   
Examples Cortisone; Dimethisterone; Ethisterone; Pregnenediones; Pregnenolone; Spironolactone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5alpha-pregn-6-ene-3beta,17alpha,20(S)-triol-20-O-beta-D-digitoxopyranoside  0   *Glycosides *Pregnenes. J Asian Nat Prod Res. 2011 Oct;13(11):1030-5
3-hydroxy-11-oxopregn-17(20)-ene-21-nitrile  0   *Pregnenes. J Med Chem 2011 Jun 9;54(11):3926-34
3,17,20-trihydroxy-4-methylpregn-8-en-7-one  0   *Pregnenes. J Nat Prod. 2010 Jul 23;73(7):1294-300
GG-52 compound  0   *Pregnenes. Lab Invest 2010 Jul;90(7):1004-15
3beta-tert-butyldimethylsilyloxy-19-hydroxy-19-vinyl-16alpha,17alpha-cyclohexapregn-5-en-20-one  0   *Pregnenes. Bioorg Khim. 2007 May-Jun;33(3):332-6
pregna-20-en-3-O-alpha-fucopyranoiside  0   *Glycosides *Pregnenes. J Asian Nat Prod Res. 2006 Jun;8(4):287-91
17alpha-acetoxy-3beta-hydroxy-6-methylene-pregna-4-en-20-one  0   *Pregnenes. Eksp Klin Farmakol. 2006 Jul-Aug;69(4):36-8
(7alpha,17alpha)-17-hydroxy-7-methyl-19-nor-17-pergen-5(10)-en-20-yn-3-one steroid  0   *Pregnenes. Int J Pharm. 2006 Feb 17;309(1-2):16-24
2'-(2-fluoro-4-pyridyl)-11beta,17,21-trihydroxy-16alpha-methyl-20-oxo-pregn-4-eno(3,2-c)pyrazole  0   *Pregnenes *Pyrazoles. Bioorg Med Chem Lett 2006 Jul 1;16(13):3454-8
periplocoside E  0   *Oligosaccharides *Pregnenes. J Pharmacol Exp Ther 2006 Feb;316(2):662-9
2'-(2-fluoro-5-pyridyl)-11,17,21-trihydroxy-16-methyl-20-oxopregn-4-eno(3,2-c)pyrazole  0   *Pregnenes *Pyrazoles. J Med Chem 2002 Nov 21;45(24):5397-405
anasteroside B  0   *Glycosides *Pregnenes. J Nat Prod 2002 Feb;65(2):153-7
3-oxo-4-pregnene-20-carboxylic acid  0   *Pregnenes. Acta Crystallogr C 2002 Jan;58(Pt 1):o22-3
9,10-seco-4-pregnene-3,9,20-trione  0   *Pregnenes. J Steroid Biochem Mol Biol 2001 Nov;78(5):493-8
sarcostin  18607-76-6   *Pregnenes. Arch Pharm Res 1998 Jun;21(3):273-7
gagaminine  41060-37-1   *Cinnamates *Pregnenes. Arch Pharm Res 1998 Jun;21(3):273-7
penupogenin  27526-87-0   *Cinnamates *Pregnenes. Arch Pharm Res 1998 Jun;21(3):273-7
20-(N,N-dimethylamino)-3-(2-methyl-2-butenamido)pregn-5-en-4-one  0   *Pregnenes. Phytochemistry 1997 Oct;46(4):771-5
20-hydroxy-21,21,21,-trifluoropregn-4-en-3-one  0   *Pregnenes Steroid 17-alpha-Hydroxylase/antagonists & inhibitors. Steroids 1997 Jun;62(6):468-73
HS 998  0   *Pregnenes. Steroids 1995 Oct;60(10):713-9
HS 974  0   *Pregnenes Isomerism. Steroids 1995 Oct;60(10):713-9
3beta,17-dihydroxy-20-oxopregn-5-en-19-al-19-(O-carboxymethyl)oxime  0   *Pregnenes Haptens. Steroids 1994 Dec;59(12):696-701
11,20-dihydroxy-4-pregnene-3-one-21-oic acid  27149-68-4   *Pregnenes. J Steroid Biochem Mol Biol 1993 Mar;44(3):305-13
guneribone  38388-19-1 Pregn-4-en-3-one, 20-methyl  *Pregnenes. Biomed Environ Mass Spectrom 1989;18(8):572
periplocoside O  116709-67-2 2H-Pyran-3(6H)-one, 2-(((3beta,20S)-20-((2,6-dideoxy-3-O-(methoxymethyl)-beta-D-arabino-hexopyranosyl)oxy)-17-hydroxypregn-5-en-3-yl)oxy)-4-methoxy-6-methyl  *Glycosides *Pregnenes Plant Extracts. Chem Pharm Bull (Tokyo) 1988;36(11):4441
periplocoside F  119902-17-9   *Glycosides *Pregnenes Plant Extracts. Chem Pharm Bull (Tokyo) 1988;36(11):4441
periplocoside K  119902-16-8 2H-Pyran-3(6H)-one, 2- (((3beta,20S)-20-((5-((O-6-deoxy-3-O-methyl-beta-D-galactopyranosyl-(1-4)-O-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-arabino-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)octahydro  *Glycosides *Pregnenes Plant Extracts. Chem Pharm Bull (Tokyo) 1988;36(11):4441
periplocoside J  119902-15-7   *Glycosides *Pregnenes Plant Extracts. Chem Pharm Bull (Tokyo) 1988;36(11):4441
periplocoside D  116709-64-9   *Glycosides *Pregnenes Plant Extracts. Chem Pharm Bull (Tokyo) 1988;36(6):2084
withangulatin A  120824-03-5   *Pregnenes Physalis. Biochem Biophys Res Commun 1989;159(3):1128
polypodoside A  119784-25-7 Cholest-7-en-6-one, 3-((2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-26-((6-deoxy-alpha-L-mannopyranosyl)oxy)-22,26-epoxy-, (3beta,5alpha,22S,25R,26S)  *Glycosides *Pregnenes Sweetening Agents Polypodium. J Nat Prod 1988;51(6):1166
periplocoside C  114828-47-6 2H-Pyran-3(6H)-one, 2-(((3beta,20S)-20-((5-((2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)tetrahydro-4-methoxy-6,9'-dimethylspiro(2H-pyran-2,3'(4'H)-(7H)pyrano(3,4-c)(1,2,5)trioxepin)-7'-yl)oxy)-17-hydroxypregn-5-en-3-yl)oxy)-4-methoxy-6-methy  *Glycosides *Pregnenes Plant Extracts. Chem Pharm Bull (Tokyo) 1988;36(3):982
periplocoside B  115743-49-2 2H-Pyran-3(6H)-one, 2-(((3beta,20S)-20-((5-((2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)tetrahydro-4-methoxy-6,9'-dimethylspiro(2H-pyran-2,3'(4'H)-(7H)pyrano(3,4-c)(1,2,5)trioxepin)-7'  *Glycosides *Pregnenes Plant Extracts. Chem Pharm Bull (Tokyo) 1988;36(3):982
periplocoside A  114828-46-5 2H-Pyran-3(6H)-one, 2-(((3beta,20S)-20-((5-((O-2-O-acetyl-6-deoxy-3-O-methyl-beta-D-galactopyranosyl-(1-4)-O-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-beta-D-rib  *Glycosides *Pregnenes Plant Extracts. Chem Pharm Bull (Tokyo) 1988;36(3):982
22-thio-23,24-bisnor-5-cholen-3-ol  116523-89-8   *Pregnenes Cholesterol Side-Chain Cleavage Enzyme/antagonists & inhibitors. J Steroid Biochem 1988;29(5):539
5-pregnen-3,20-diol glucoside  99207-79-1   *Glucosides *Pregnenes. J Biol Chem 1985;260(29):15410
22-amino-23,24-bisnor-5-cholen-3-ol  78949-97-0   *Pregnenes Steroid 17-alpha-Hydroxylase/antagonists & inhibitors. Arch Biochem Biophys 1985;242(1):297
asterogenol  75921-90-3   *Pregnenes. Steroids 1984;44(1):67
5-dehydromalouetine  21632-05-3   *Pregnenes. C R Seances Acad Sci (III) 1984;298(10):275
20-hydroxy-3-oxo-4-pregnen-21-carboxylic acid  2681-56-3 Pregn-4-en-21-oic acid, 20-hydroxy-3-oxo-, (20R)  *Pregnenes. J Steroid Biochem 1982;17(1):51
TX 3047  78822-05-6 Ethanaminium, N,N-diethyl-2-(((3beta)-20-hydroxypregn-5-en-3-yl)oxy)-N-methyl-, salt with 4-methylbenzenesulfonic acid (1:1)  *Pregnenes. Br J Pharmacol 1981;72(4):597
15 beta,17 alpha,20 beta-trihydroxy-4-pregnen-3-one  0   *Pregnenes. J Steroid Biochem 1981;14(9):901
SC 27169  41020-87-5   *Pregnenes. Clin Pharmacol Ther 1981;30(2):218
16 beta-methyl-5 alpha-delta 9(11)-pregnene-3 beta,17 alpha,21-triol-20-one-3 beta,21-diacetate  50633-44-8 Pregn-9(11)-en-20-one, 3,21-bis(acetyloxy)-17-hydroxy-16-methyl-, (3beta,5alpha,16beta)  *Pregnenes. Yao Hsueh Hsueh Pao 1981;16(5):356
5-pregnene-3 beta,17 alpha,20 alpha-triol  903-67-3   *Pregnenes. Endokrinologie 1979 Apr;74(1):42-6
glycoside H2  73529-43-8 beta-D-Galactopyranoside, (3beta,16alpha,20S)-3-((4-O-(2-O-acetyl-6-deoxy-3-O-methyl-beta-D-galactopyranosyl)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-16-hydroxypregn-5-en-20-yl O-beta-D-glucopyranosyl-(1-6)-O-beta-D-glucopyranosyl-(1-2)-6-d  *Glycosides *Pregnenes. Chem Pharm Bull (Tokyo) 1980;28(1):163
4-pregnene-3 alpha,20 alpha-diol  15780-16-2 (3 alpha,20S)-pregn-4-ene-3,20-diol  *Pregnenes. Acta Endocrinol (Copenh) 83(3):583;1976; Acta Endocrinol (Copenh) 83(3):604;1976; J Steroid Biochem 11(1A):227;1979; Steroids 33(4):467;1979
holaphyllaminol  17941-92-3 Pregn-5-en-20-ol, 3-amino-, (3beta,20R)  *Pregnenes. Cell Mol Biol 23(3):241;1978
irehdiamine A  3614-57-1 pregn-5-ene-3 beta,20 alpha-diamine  *Pregnenes. Cold Spring Harbor Symp Quant Biol 42(pt 1):90;1977; Proc Natl Acad Sci USA 75(9):4286;1978
anagestone  2740-52-5 17-hydroxy-6 alpha-methylpregn-4-en-20-one  *Pregnenes Progesterone Congeners. J Natl Cancer Inst 60(6):1351;1978
methyl-1alpha, 7alpha-dihydroxy-3-oxopregn-4-en-21-oate  58497-24-8 Pregn-4-en-21-oic acid, 1,7-dihydroxy-3-oxo-, methyl ester, (1alpha,7alpha)  *Pregnenes. Steroids 30(3):363;1977
20,20-methyleneoxy-3-oxo-4-pregnen-21-acid methylester  0   *Pregnenes. Pharmazie 32(4):221;1977
20-methyl-20-(2-hydroxyethoxy)-5-pregnene-3 beta,17 alpha-diol  0   *Pregnenes. Steroids 29(2):261;1977
asterone  37717-02-5 5 alpha-pregn-9(11)-ene-3 beta,6 alpha-diol-20-one  *Pregnenes Saponins. Anal Biochem 81:196;1977; Comp Biochem Physiol 54(4):561;1976; Steroids 22(6):835;1973
20-phenyl-5-pregnene-3 beta,20-diol  0   *Pregnenes. J Biol Chem 251(3):7336;1976; J Biol Chem 251(7):2087;1976
23,24-dinor-5-cholene-3,21-diol  0   *Pregnenes. Steroids 22(2):239;1973
20-methylpregn-5-ene-3,20-diol  20976-92-5   *Pregnenes. Steroids 22(2):239;1973
3beta-acetoxy-18-dimethoxy-20-oxo-delta(16)-5alpha-pregnene  0   *Pregnenes. Helv Chim Acta 56(1):2698;1973
6alpha-methylpregn-4-ene-3,11,20-trione  3642-85-1   *Pregnenes. Cancer Chemother Rep 55(3):265;1971
20-hydroperoxy-5-pregnen-3-beta-ol  0   *Pregnenes. Steroids 21(4):521;1973
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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