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Pregnenolone Carbonitrile

More information in Books or onNLM PubMed
Definition: A catatoxic steroid and microsomal enzyme inducer having significant effects on the induction of cytochrome P450. It has also demonstrated the potential for protective capability against acetaminophen-induced liver damage.  DF: PCN    Other names Pregnenolone 16 alpha Carbonitrile; Carbonitrile, Pregnenolone; 16 alpha-Carbonitrile, Pregnenolone; Pregnenolone Carbonitrile, (3 beta,16 beta)-Isomer; Pregnenolone Carbonitrile, (3 beta)-Isomer; Pregnenolone 16 alpha-Carbonitrile; PCN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
16-cyano-3-hydroxypregn-5-en-20-one cyclopentyl ether  53962-58-6 16 alpha-cyano-3 beta-cyclopentyloxypregn-5-en-20-one  Pregnenolone Carbonitrile/*analogs & derivatives. Biochem Soc Trans 5(5):1378;1978; Biomed Mass Spectrom 5(7):460;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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