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Prodigiosin

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Definition: 4-Methoxy-5-((5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl)- 2,2'-bi-1H-pyrrole. A toxic, bright red tripyrrole pigment from Serratia marcescens and others. It has antibacterial, anticoccidial, antimalarial, and antifungal activities, but is used mainly as a biochemical tool.  an antibiotic from Serratia marcescens & others; do not confuse with PRODIGIOZAN, another antibiotic from same source; /biosyn permitted if by micro-organism   
Pharmacological Action Anti-Bacterial Agents
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(p-hydroxybenzyl)prodigiosin  0   Prodigiosin/*analogs & derivatives. J Nat Prod. 2008 Nov;71(11):1970-2
prodigiosin R1  0   Prodigiosin/*analogs & derivatives. J Nat Prod 2008 Jul;71(7):1265-7
PG-L-1 compound  0   Prodigiosin/*analogs & derivatives NADPH Oxidase/antagonists & inhibitors. J Biochem 2008 Jan;143(1):107-15
streptorubin B  0   Prodigiosin/*analogs & derivatives. Chem Biol 2008 Feb;15(2):137-48
undecylprodiginine  0   Prodigiosin/*analogs & derivatives. J Antibiot (Tokyo) 1975 Mar;28(3):194-9
ethyl 5-((3-methoxy-5-(1H-pyrrol-2-yl)-1H-pyrrol-2-yl)methylene)-2,4-dimethyl-5H-pyrrole-3-carboxylate  0   Prodigiosin/*analogs & derivatives. J Med Chem 2007 Apr 5;50(7):1528-36
butylcycloheptylprodigiosin  0   Prodigiosin/*analogs & derivatives. Angew Chem Int Ed Engl 2005 Apr 29;44(18):2777-81
heptylprodigiosin  0   Prodigiosin/*analogs & derivatives. J Nat Toxins 2002 Dec;11(4):367-77
4-benzyloxy-5-((5-undecyl-2H-pyrrol-2-ylidene)methyl)-2,2'-bi-1H-pyrrole  0   Prodigiosin/*analogs & derivatives. J Immunol 1999 Jun 15;162(12):7102-9
metacycloprodigiosin  0   Prodigiosin/*analogs & derivatives. J Antibiot (Tokyo) 1996 Jan;49(1):86-90
prodigiosin 25C  14960-80-6   Prodigiosin/*analogs & derivatives Pigments, Biological. J Antibiot (Tokyo) 1992 Aug;45(8):1295-1302
butyl-meta-cycloheptylprodiginine  56208-07-2   Prodigiosin/*analogs & derivatives Pigments, Biological. J Antibiot (Tokyo) 1991;44(2):187
undecylprodigiosin  52340-48-4   Prodigiosin/analogs & derivatives.
Pharma Action Anti-Bacterial Agents ; Immunosuppressive Agents 		J Gen Microbiol 1985;131 (Pt 9):2431
4-methoxy-2,2'-bipyrrole-5-carboxaldehyde  10476-41-2   Prodigiosin/*analogs & derivatives. J Clin Microbiol 1983;17(3):476
prodiginine  24311-00-0   Prodigiosin/*analogs & derivatives Pigments, Biological. J Antibiot (Tokyo) 28(3):194;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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