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Progesterone

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Definition: The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.     
Pharmacological Action Progestins
See Also Receptors, Progesterone
Examples Algestone; 20-alpha-Dihydroprogesterone; Hydroxyprogesterones; Medroxyprogesterone 		Other names Progesterone, (9 beta,10 alpha)-Isomer; Progesterone, (17 alpha)-Isomer; Progesterone, (13 alpha,17 alpha)-(+-)-Isomer; PregnenedioneDrugs* : PROMETRIUM; PROGESTASERT; PROGESTERONE; ENDOMETRIN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
16-methyl-17-benzoyloxypregnen-4-en-3,20-dione  0   Progesterone/*analogs & derivatives. Andrologia 2011 Aug;43(4):225-32
17-hydroxyprogesterone-3-O-carboxymethyloxime  0   *Oximes Progesterone/*analogs & derivatives. J Immunoassay Immunochem 2009;30(2):186-96
Autoimmune progesterone dermatitis  0   *Autoimmune Diseases Progesterone/adverse effects.
21-succinyloxy-6,19-epoxyprogesterone  0   Progesterone/*analogs & derivatives. ChemMedChem 2008 Dec;3(12):1869-77
6,19-oxidoprogesterone  0   Progesterone/*analogs & derivatives. Biochemistry 2007 Dec 11;46(49):14044-57
17-p-bromophenylcarbamoyloxypregn-4-ene-3,20-dione  0   *Carbamates Progesterone/*analogs & derivatives 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. J Steroid Biochem Mol Biol 2007 Oct;107(1-2):48-56
17-phenylcarbamoyloxypregn-4-ene-3,20-dione  0   *Carbamates Progesterone/*analogs & derivatives 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. J Steroid Biochem Mol Biol 2007 Oct;107(1-2):48-56
4-pregnene-3,20-dione  0   Progesterone/*analogs & derivatives. Fertil Steril. 2004 Apr;81(4):1007-12
6,19-methanoprogesterone  0   Progesterone/*analogs & derivatives. Org Biomol Chem. 2003 Mar 21;1(6):939-43
16,17-cyclohexano-4,5-dihydroprogesterone  0   *Cyclohexanes Progesterone/*analogs & derivatives Stereoisomerism. Bioorg Khim 2002 May-Jun;28(3):261-8
nepapakistamine A  0   Progesterone/*analogs & derivatives. J Nat Prod 2001 Jun;64(6):842-4
vaganine D  0   Progesterone/*analogs & derivatives. J Nat Prod 2001 Jun;64(6):842-4
Crinone  0   Progesterone/*analogs & derivatives. Fertil Steril 1999 Nov;72(5):823-9CRINONE
18-oxo-18-vinylprogesterone  0   Progesterone/*analogs & derivatives. Biochim Biophys Acta 1998 Oct 14;1388(1):35-44
16,17-cyclopropanoprogesterone  0   Progesterone/*analogs & derivatives Receptors, Progesterone/agonists. Biull Eksp Biol Med 1998 May;125(5):532-4
Progest  0   *Progesterone Estrogen Replacement Therapy. Lancet 1998 Apr 25;351(9111):1255-6
caproxyprogesterone  0   Progesterone/*analogs & derivatives. Cancer Res 1998 Feb 1;58(3):392-5
21-hydroxy-6,19-oxidoprogesterone  0   Progesterone/*analogs & derivatives Receptors, Glucocorticoid/antagonists & inhibitors. Mol Pharmacol 1997 Oct;52(4):749-54
17-acetoxy-9-fluoro-6-methylprogesterone  0   Progesterone/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1997 Feb;45(2):421-3
ZK 136798  0   *Androstenes Progesterone/antagonists & inhibitors. J Steroid Biochem Mol Biol 1996 Sep;59(1):75-82
3,17-dihydroxy-7-(4-methoxyphenyl)-androst-5-ene 3,17-diacetate  168412-87-1   *Androstenols *Anisoles Progesterone/antagonists & inhibitors. Steroids 1995 Jun;60(6):470-2
3,17-dihydroxy-7-(4-hydroxyphenyl)-androst-5-ene 3,17-diacetate  0   *Androstenols *Phenols Progesterone/antagonists & inhibitors. Steroids 1995 Jun;60(6):470-2
progesterone-11HS-horseradish peroxidase  0   *Horseradish Peroxidase Progesterone/*analogs & derivatives. J Immunoassay 1995 May;16(2):137-53
21-hydroxy-11,19-oxidopregn-4-ene-3,20-dione  0   Progesterone/*analogs & derivatives. Steroids 1995 Mar;60(3):268-71
21-hydroxy-6,19-oxidopregn-4-ene-3,20-dione  0   Progesterone/*analogs & derivatives. Steroids 1995 Mar;60(3):268-71
4-cyanoprogesterone  0   Progesterone/*analogs & derivatives. J Enzym Inhib 1994;8(1):17-23
11,19-oxidoprogesterone  1913-28-6   Progesterone/*analogs & derivatives. Mol Pharmacol 1995 Mar;47(3):535-43
6-fluoroprogesterone  158091-62-4   Progesterone/*analogs & derivatives Fluorine Radioisotopes. Appl Radiat Isot 1994 Jul;45(7):811-3
2-hydroxy-4-pregnene-3,20-dione  604-28-4   Progesterone/*analogs & derivatives. J Steroid Biochem Mol Biol 1994 Jun;49(2-3):213-26
progesterone-3-(O-carboxymethyl oxime)-horseradish peroxidase  0   *Horseradish Peroxidase Progesterone/*analogs & derivatives. Biochem Mol Biol Int 1993 Nov;31(3):553-63
progesterone-11-hemisuccinyl-bovine serum albumin  0   *Serum Albumin, Bovine Progesterone/*analogs & derivatives. Biochem Mol Biol Int 1993 Nov;31(3):553-63
pentarane B  58212-84-3 16,24-Cyclo-21-norchol-4-en-3-one, 17-acetyl-6-methyl-, (6alpha,16beta,17alpha)  Progesterone/*analogs & derivatives. Mol Cell Biochem 1993 Aug 25;125(2):153-61
pentarane A  38522-51-9 16,24-Cyclo-21-norchol-4-en-3-one, 17-acetyl-, (16beta,17alpha)  Progesterone/*analogs & derivatives. Mol Cell Biochem 1993 Aug 25;125(2):153-61
progesterone 6-hemimaleate  152881-19-1   *Maleates Progesterone/*analogs & derivatives. J Reprod Fertil 1993 Mar;97(2):557-61
progesterone 6-hemisuccinate  50909-93-8   *Succinates Progesterone/*analogs & derivatives. J Reprod Fertil 1993 Mar;97(2):557-61
7-(carboxyethylthio)progesterone  40845-01-0   Progesterone/*analogs & derivatives. J Reprod Fertil 1993 Mar;97(2):557-61
progesterone 3-(O-carboxymethyl)oxime-bovine serum albumin  0   *Serum Albumin, Bovine Progesterone/*analogs & derivatives. Neuroendocrinology 1992 Jan;55(1):1-8
18-ethynylprogesterone  115940-37-9   Progesterone/*analogs & derivatives. Am J Physiol 1991;260(6 Pt 2):P828
18-vinylprogesterone  80899-87-2   Progesterone/*analogs & derivatives. Am J Physiol 1991;260(6 Pt 2):P828
6-methylprogesteron-17-pivalate  86098-91-1   Progesterone/*analogs & derivatives. Acta Crystallogr C 1991;47(Pt 2):385
progesterone-11-bovine serum albumin  0   *Serum Albumin Progesterone/*analogs & derivatives. Brain Res 1991;538(1):176
allylestriol  26583-08-4   Progesterone/*analogs & derivatives. Dev Comp Immunol 1990;14(4):457
progesterone-3-ethanolimine  130369-85-6   Progesterone/*analogs & derivatives. Steroids 1990;55(8):366
3,20-dioxopregn-4-ene-18'-carboxaldehyde cyclic 18'-(1,2-ethandiylmercaptal)  123376-04-5   Progesterone/*analogs & derivatives. Steroids 1990;55(6):271
18-ethylenedithioprogesterone  134028-69-6   Progesterone/*analogs & derivatives. Steroids 1990;55(6):271
17-acetoxy-6,16-dimethylene-4-pregnene-3,20-dione  80097-73-0   Progesterone/*analogs & derivatives. Biochem Pharmacol 1989;38(21):3669
17-hydroxy-6-dehydroprogesterone  2477-60-3   Progesterone/*analogs & derivatives. J Chromatogr 1988;456(2):427
2'-methyl-16,17-cyclohexaneprogesterone  116169-22-3   Progesterone/*analogs & derivatives. Bioorg Khim 1988;14(6):828
21,21-dichloroprogesterone  117038-59-2   Progesterone/*analogs & derivatives. Arch Biochem Biophys 1988;264(2):462
hydroxyprogesterone hemisuccinate bovine serum albumin tetramethylrhodamine isothiocyanate  0   *Rhodamines *Serum Albumin, Bovine Progesterone/*analogs & derivatives. Diagn Cytopathol 1988;4(1):42
11-progesteryl-2-carboxymethyltyramine-4-(10-methyl)acridinium-9-carboxylate  113578-24-8   *Acridines Progesterone/*analogs & derivatives Luminescent Measurements. Ann Clin Biochem 1988;25(Pt 1):27
Menstrogen  0   *Ethinyl Estradiol *Ethisterone *Progesterone Contraceptives, Oral, Combined. Ned Tijdschr Geneeskd 1988;132(1):29
progesterone 12-succinyltyrosine methyl ester  110988-79-9   Progesterone/*analogs & derivatives. J Chromatogr 1987;404(1):258
progesterone 11-succinyltyrosine methyl ester  110988-78-8   Progesterone/*analogs & derivatives. J Chromatogr 1987;404(1):258
nymfon-orion  62570-10-9   *Chorionic Gonadotropin *Gonadotropin-Releasing Hormone *Progesterone Drug Combinations. Vet Med Nauki 1986;23(5):72
11-progesteryl-2-succinoyltyramine-4-(10-methyl)acridinium-9-carboxylate  99195-33-2   *Acridines Progesterone/*analogs & derivatives Haptens. Clin chem 1985;31(10):1664
2-hydroxymethyleneprogesterone  1452-25-1 Pregn-4-ene-3,20-dione, 2-(hydroxymethylene)  Progesterone/*analogs & derivatives. Biochem J 1985;226(2):469
2-cyanoprogesterone  95160-20-6   Progesterone/*analogs & derivatives 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Biochem J 1985;226(2):469
17-(phenylseleno)progesterone  74137-00-1   Progesterone/*analogs & derivatives. J Med Chem 1983;26(9):1320
21-(phenylseleno)progesterone  74136-99-5   Progesterone/*analogs & derivatives. J Med Chem 1983;26(9):1320
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