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Promethazine

More information in Books or onNLM PubMed
Definition: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.     
Pharmacological Action Anti-Allergic Agents; Antipruritics; Histamine H1 Antagonists 		Other names Proazamine; Hydrochloride, Promethazine; Rumergan; Remsed; Pyrethia; Prothazin; Promethazine Hydrochloride; Prometazin; Promet; Pipolphen; Pipolfen; Phensedyl; Phenergan; Phenargan; Isopromethazine; Diprazin; Diphergan; AtosilDrugs* : ZIPAN-25; PROMETH PLAIN; PROMETH VC W/ CODEINE; PROMETHAZINE VC W/ CODEINE; PROMETHAZINE HYDROCHLORIDE; PROMETHAZINE WITH CODEINE; ZIPAN-50; PROMETHEGAN; PROMETHAZINE; PROMETH HYDROCHLORIDE,PHENYLEPHRINE HYDROCHLORIDE W/CODEINE PHOSPHATE; PROMETHAZINE HYDROCHLORIDE AND CODEINE PHOSPHATE; PHENERGAN W/ CODEINE; PROMETH FORTIS; PROMETHAZINE PLAIN; REMSED; PROMETHACON; PHERAZINE W/ CODEINE; PHERAZINE VC W/ CODEINE; PHENERGAN; PROMETHAZINE HYDROCHLORIDE PLAIN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Night Nurse  0   *Acetaminophen *Dextromethorphan *Phenylpropanolamine *Promethazine Drug Combinations. Eye 2001 Apr;15(Pt 2):248-9
desmonomethylpromazine sulfoxide  0   Promethazine/*analogs & derivatives. J Chromatogr Sci 2001 Feb;39(2):70-2
promethazine sulfoxide  7640-51-9   Promethazine/*analogs & derivatives. Free Radic Biol Med 1996;20(6):807-11
thiazinamium  58-34-4   *Promethazine.
N-desmethylpromethazine  37707-23-6   Promethazine/*analogs & derivatives. Drug Metab Dispos Biol Fate Chem 1993 Jan-Feb;21(1):24-9
Kominek's mixture  81424-60-4 Benzoic acid, 2-(acetyloxy)-, mixt. with 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine, 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 2-methyl-2-propyl-1,3-propanediyl dicarbamate and N,N,alpha-trimethyl-10H-phenothiazone-10-ethanamine mono  *Aspirin *Chlorpromazine *Meprobamate *Phenobarbital *Promethazine Drug Combinations. Stomalologiia (Mosk) 1981;60(6):24
Synalgos  79102-58-2 Benzoic acid, 2-(acetyloxy)-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, N-(4-ethoxyphenyl)acetamide and N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine monohydrochloride  *Aspirin *Caffeine *Phenacetin *Promethazine Drug Combinations. Oral Surg 47(6):513;1979
thiazinamium sulfoxide  40746-00-7   Promethazine/*analogs & derivatives. J Chromatogr 128(1):208;1976; J Pharm Sci 67(8):1147;1978
codeine, dioxethedrin, promethazine drug combination  0   *Codeine *Promethazine *Propanolamines Drug Combinations. Fortschr Med 94(34):2051;1976
amobarbital, glutethimide, promethazine drug combination  79173-15-2 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)-, mixt. with 3-ethyl-3-phenyl-2,6-piperidinedione and N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine  *Amobarbital *Glutethimide *Promethazine Drug Combinations. Arch Kriminol 153(1):36;1974
promethazine tetraiodomercurate  52653-51-7   Promethazine/*analogs & derivatives. Acta Pol Pharm 30(4):395;1973
dioxopromethazine  13754-56-8 10H-Phenothiazine-10-ethanamine,N,N,alpha-trimethyl-,5,5-dioxide  Promethazine/*analogs & derivatives. Pharmazie 28(10):683;1973; Pharmazie 32(8/9):489;1977; Pharmazie 33(10):686;1978
aminopyrine, atropine, codeine, promethazine drug combination  76741-94-1   *Aminopyrine *Atropine *Codeine *Promethazine Drug Combinations. Eksp Med Morfol 12(1):1;1973
Germakhellin  77416-69-4 10H-Phenothiazine-10-ethanaminium, N,N,N,alpha-tetramethyl-, methyl sulfate, mixt. with 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6-dione and 4,9-dimethoxy-7-methyl-3-(1-piperazinylmethyl)-5H-furo(3,2-g)(1)benzopyran-5-one  Drug Combinations Dyphylline/*analogs & derivatives Khellin/*analogs & derivatives Promethazine/*analogs & derivatives Asthma/drug therapy.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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