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Dextropropoxyphene

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Definition: A narcotic analgesic structurally related to METHADONE. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect.     
Pharmacological Action Analgesics, Opioid; Narcotics 		Other names D-Propoxyphene; Hydrochloride, Propoxyphene; D Propoxyphene; Propoxyphene Sulfate, (S-(R*,S*))-Isomer; Propoxyphene Phosphate, (S-(R*,S*))-Isomer; Propoxyphene Maleate, (+)-Isomer; Propoxyphene Hydrochloride, (S-(R*,R*))-Isomer; Propoxyphene Hydrochloride, (R-(R*,S*))-Isomer; Propoxyphene Hydrochloride, (R-(R*,R*))-Isomer; Propoxyphene Hydrochloride, (R*,R*)-(+-)-Isomer; Propoxyphene Hydrochloride; Propoxyphene; DarvonDrugs* : KESSO-GESIC; PROPOXYPHENE HYDROCHLORIDE 65; DOLENE; PROPHENE 65; PROPOXYPHENE HYDROCHLORIDE; DARVON
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
propoxyphene napsylate  17140-78-2 2-Naphthalenesulfonic acid, compd. with (S-(R*,S*))-3-(dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)p- ropyl propanoate (1:1)  Dextropropoxyphene/*analogs & derivatives. PROPACET 100; PROPOXYPHENE HYDROCHLORIDE AND ACETAMINOPHEN; DARVOCET A500; DARVON-N; DOLENE AP-65; DARVOCET-N 100; PROPOXYPHENE NAPSYLATE AND ACETAMINOPHEN; NOVRAD; DARVOCET; WYGESIC; DARVOCET-N 50
norpropoxyphene carbinol  42576-08-9   Dextropropoxyphene/*analogs & derivatives. Acta Pharmacol Toxicol (Copenh) 1983;53(4):257
DP-neuralgen  86290-92-8 Benzoic acid, 2-(acetyloxy)-, mixt. with (S-(R*,S*))-3-(dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)propyl propanoate 2-naphthalenesulfonate and N-(4-ethoxyphenyl)acetamide  *Aspirin *Phenacetin Drug Combinations Dextropropoxyphene/*analogs & derivatives. Cas Lek Cesk 1983;122(3):83
Doleron  63482-28-0 10H-Phenothiazine-10-carboxylic acid, 2-(diethylamino)ethyl ester, monohydrochloride, mixt. with 2-(acetyloxy)benzoic acid, 1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione and (S-(R*,S*))-3-(dimethylami  *Antipyrine *Aspirin *Phenothiazines *Dextropropoxyphene Drug Combinations. Int J Oral Surg 1979;8(6):435
aspirin, dextropropoxyphene drug combination  0 Benzoic acid, 2-(acetyloxy)-, mixt. with (S-(R*,S*))-3-(dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)propyl propanoate 2-naphthalenesulfonate  *Aspirin *Dextropropoxyphene Drug Combinations. Int J Oral Surg 1979;8(6):435DARVON COMPOUND; DARVON-N W/ ASA; PROPOXYPHENE COMPOUND-65; DARVON COMPOUND-65; PROPOXYPHENE COMPOUND 65; COMPOUND 65; PROPOXYPHENE HYDROCHLORIDE W/ ASPIRIN AND CAFFEINE; DARVON W/ ASA
fenalgin  77257-34-2 Benzoic acid, 2-(acetyloxy)-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, (S-(R*,S*))-3-(dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)propyl propanoate 2-naphthalenesulfonate, 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione and N-(4  *Caffeine *Acetaminophen *Phenobarbital *Dextropropoxyphene Drug Combinations. Bratisl Lek Listy 71(4):421;1979
propoxyphene carbinol  37947-49-2   Dextropropoxyphene/*analogs & derivatives. J Chromatogr 134:187;1977
acetaminophen, dextropropoxyphene, drug combination  39400-85-6   *Acetaminophen *Dextropropoxyphene Drug Combinations.
Pharma Action Analgesics 		Br Med J 1(6007):460;1976; Br Med J 1(6162):551;1979; Therapie 1982;37(3):321
propoxyphene phenylbutazone  0   Phenylbutazone/*analogs & derivatives Dextropropoxyphene/*analogs & derivatives. Minerva Urol 24(4):145;1972
lenigesial 1-carboxymethyl-3,7-dimethylxanthine  52387-20-9 1H-purine-1-acetic acid, 2,3,6,7-tetrahydro-3,7-dimethyl-2,6-dioxo-, compd. with (S-(R*,S*))-3-(dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)propyl propanoate (1:1)  *Dextropropoxyphene Drug Combinations Theobromine/*analogs & derivatives. Minerva Anestesiol 38(1):28;1972; Minerva Anestesiol 38(5):297;1972
CIBA 44328  54364-09-9 d-2-(dimethylaminomethyl)-1,2-diphenyl-3-butene-2-ol propionate maleate  Dextropropoxyphene/*analogs & derivatives. Br Med J 4(5938):196;1974
propofan  0   *Acetaminophen *Aspirin *Chlorpheniramine *Dextropropoxyphene Drug Combinations. Ann Odontostomatol (Lyon) 29(5):205;1972
spasmo-tropaxl  0   *Aminopyrine *Diphenylacetic Acids *Flupenthixol *Dextropropoxyphene Drug Combinations.
proxifezone  34427-79-7   *Phenylbutazone *Dextropropoxyphene Drug Combinations.
probunafon  31852-19-4   Dextropropoxyphene/*analogs & derivatives. Z Allgemein Med 46(12):626;1970
norpropoxyphene  3376-94-1   Dextropropoxyphene/*analogs & derivatives. Clin Chem 22(8):1319;1976; J Chromatogr 132:287;1977; J Chromatogr 140:280;1977
Midalgyl  0   *Ascorbic Acid *Phenylbutazone *Dextropropoxyphene *Salicylamides Analgesics Suppositories.
oxiphene  126-04-5 4-dimethylamino-1,2-diphenyl-3-methyl-2-butanol  *Amino Alcohols Dextropropoxyphene. Il Farmaco 27(7):582;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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