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Propranolol

More information in Books or onNLM PubMed
Definition: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.     
Pharmacological Action Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Vasodilator Agents 		Other names Dexpropranolol; Hydrochloride, Propranolol; AY20694; AY 20694; Rexigen; Propranolol Hydrochloride; Propanolol; Obzidan; Obsidan; Inderal; Dociton; Betadren; Avlocardyl; Anapriline; Anaprilin; AY-20694Drugs* : PROPRANOLOL HYDROCHLORIDE; INDERAL LA; INDERAL; PROPRANOLOL HYDROCHLORIDE INTENSOL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-hydroxypropranolol  0   Propranolol/*analogs & derivatives. Bioorg Med Chem Lett. 2009 Jun 1;19(11):3085-7
1-(1,1-dimethylethylamino)-3-(1-naphthoxy)-2-propanol hydrochloride  0   Propranolol/*analogs & derivatives. Pol J Pharmacol 2004 Jan-Feb;56(1):105-11
propranolol stearate  0   Propranolol/*analogs & derivatives. J Control Release 2002 Aug 21;82(2-3):223-36
fluoropropranolol  0   Propranolol/*analogs & derivatives Fluorine Radioisotopes Ligands. Genomics 2000 Jan 1;63(1):891-6
palmitoyl propranolol  0   Propranolol/*analogs & derivatives. Int J Pharm 1999 Sep 20;186(2):177-89
butyryl propranolol  0   Propranolol/*analogs & derivatives. Life Sci 1998;62(14):1231-41
propranolol FD  149825-35-4   Propranolol/*analogs & derivatives. Gen Pharmacol 1993 May;24(3):721-5
O-isovaleryl propranolol  111422-10-7   Propranolol/*analogs & derivatives. J Pharmacobiodyn 1992 Sep;15(9):535-40
propranolol laurate  138656-55-0   Propranolol/*analogs & derivatives. Pharm Res 1992 Nov;9(11):1507-9
O-acetylpropranolol  2293-03-0 Ethanol, 1-((1-methylethyl)amino)-2-(1-naphthalenyloxy)-, acetate (ester)  Propranolol/*analogs & derivatives. J Pharm Pharmacol 1990;42(5):356
1-(1-(2-benzodioxanylmethyl)-4-piperidiyl)amino-3-(1-naphthoxy)-2-propanol  131184-64-0   Piperoxan/*analogs & derivatives Propranolol/*analogs & derivatives. Farmaco 1989;44(11):1109
1-((2-(5-dimethylamino)naphthalene-1-sulfonylaminoethyl)amino)-3-(1-naphthaleneoxy)-2-propanol  65118-46-9   *Dansyl Compounds Propranolol/*analogs & derivatives. Cell Biol Int Rep 1989;13(8):667
4-methylpropranolol  2007-69-4   Propranolol/*analogs & derivatives. J Chromatogr 1989;489(2):438
4,8-dihydroxypropranolol  114662-00-9 1,5-Naphthalenediol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)  Propranolol/*analogs & derivatives. Drug Metab Dispos 1988;16(2):212
4,6-dihydroxypropranolol  114662-06-5   Propranolol/*analogs & derivatives. Drug Metab Dispos 1988;16(2):212
1-(1-hydroxy-2-propylamino)-3-(1-naphthoxy)-2-propanol  103478-75-7   Propranolol/*analogs & derivatives. J Med Chem 1986;29(10):2004
N-cyclopentyldeisopropylpropranolol  2116-33-8   Propranolol/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 1985;48(2):255
spiroprop  138230-23-6   *Propranolol *Spironolactone Drug Combinations. Drug Ther Bull 1985;23(8):31
Inderex  83952-37-8   *Bendroflumethiazide *Propranolol Drug Combinations. Br J Clin Pract 1985;39(3):98
4-hydroxypropranolol glucuronide  94731-13-2 beta-D-Glucopyranosiduronic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-1-naphthalenyl, (5alpha,6beta)  Propranolol/*analogs & derivatives. Drug Metab Dispos 1984;12(6):749
3,4-dihydroxypropranolol  89710-82-7   Propranolol/*analogs & derivatives. J Med Chem 1984;27(7):857
4'-hydroxypropranolol sulfate ester  87075-33-0   Propranolol/*analogs & derivatives. J Chromatogr 1984;305(1):250
4-hydroxypropranolol glycol  36112-96-6   Propranolol/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 1983;42(2):235
obsilazin  0   *Dihydralazine *Propranolol Drug Combinations. Kardiologiia 1983;23(12):29
1,1-diethoxy-3-(1-naphthoxy)-2-propanol  82540-40-7   Propranolol/*analogs & derivatives. J Pharm Sci 1983;72(8):863
dansylpropranolol  81591-69-7 1-Naphthalenesulfonic acid, 5-(dimethylamino)-, 1-(((1-methylethyl)amino)methyl)-2-(1-naphthalenyloxy)ethyl ester  Propranolol/*analogs & derivatives. Biochim Biophys Acta 1983;732(2):441
propranolol N-aldonitrone  84418-34-8   Propranolol/*analogs & derivatives. J Med Chem 1983;26(3):458
N-hydroxypropranolol  84418-31-5   Propranolol/*analogs & derivatives. J Med Chem 1983;26(3):455
N-nitrosopropranolol  84418-35-9   *Nitrosamines Propranolol/*analogs & derivatives. J Med Chem 1983;26(3):455
docidrazin  0   *Bendroflumethiazide *Hydralazine *Propranolol Drug Combinations. ZFA (Stuttgart) 1982;58(30):1669
inderide  69136-73-8   *Hydrochlorothiazide *Propranolol Drug Combinations. Biopharm Drug Dispos 1982;3((1):55INDERIDE LA 120/50; INDERIDE LA 80/50; PROPRANOLOL HYDROCHLORIDE & HYDROCHLOROTHIAZIDE; INDERIDE-40/25; INDERIDE LA 160/50; PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE; INDERIDE-80/25
4'-methylthiopropranolol  73315-35-2 2-Propanol, 1-((1-methylethyl)amino)-3-((4-(methylthio)-1-naphthalenyl)oxy)  Propranolol/*analogs & derivatives. J Pharmacol Ex Ther 1981;219(3):685
N-(S-methyl)mercaptoethylpropranolol  75790-55-5 2-Propanol, 1-((2-(methylthio)ethyl)amino)-3-(1-naphthalenyloxy)  Propranolol/*analogs & derivatives. Biochimie 1980;62(7):455
N-mercaptoethylpropranolol  75790-56-6 2-Propanol, 1-((2-mercaptoethyl)amino)-3-(1-naphthalenyloxy)  Propranolol/*analogs & derivatives. Biochimie 1980;62(7):455
propranolol mustard  73631-12-6 2-Propanol, 1-(bis(2-chloroethyl)amino)-3-(1-naphthalenyloxy)  *Nitrogen Mustard Compounds Propranolol/*analogs & derivatives. J Pharm Sci 1980;69(2):190
propranolol glucuronide  66322-66-5 beta-D-Glucopyranosiduronic acid, 1-(((1-methylethyl)amino)methyl)-2-(1-naphthalenyloxy)ethyl  Propranolol/*analogs & derivatives. Clin Pharmacol Ther 26(6):686;1979
alpha-methylpropranolol  21912-00-5   Propranolol/*analogs & derivatives. Clin Exp Pharmacol Physiol 5(6):579;1978
N-(2-hydroxy-3-naphthyloxypropyl)-N'-dansylethylenediamine  0   Propranolol/*analogs & derivatives. Brain Res 15(2):377;1978
ORF 12592  81907-79-1   Propranolol/*analogs & derivatives. Arch Int Pharmacodyn Ther 224:102;1976; Arch Int Pharmacodyn Ther 233(2):270;1978
9-aminoacridylpropranolol  60566-40-7   Propranolol/*analogs & derivatives. Brain Res 128(3):532;1977; Exp Eye Res 1979;29(4):327; Experientia 32(11):1387;1976; Neurology 28(8):850;1978
propranolol glycol  36112-95-5   Propranolol/*analogs & derivatives. J Chromatogr 123(1):185;1976
N-desisopropylpropranolol  20862-11-7   Propranolol/*analogs & derivatives. J Chromatogr 123(1):185;1976
BDGJ  19343-23-8 1-isopropylamino-3-(1-naphthylamino)-2-propanol  Propranolol/*analogs & derivatives. Pol J Pharmacol Pharm 25(1):23;1973
pranolium  50643-33-9 2-hydroxy-N,N-dimethyl-N-(1-methylethyl)-3-(1-naphthalenyloxy)-1-propanaminium  Propranolol/*analogs & derivatives.
Pharma Action Anti-Arrhythmia Agents 		Can J Physiol Pharmacol 1979;57(6):637; Circulation 57(3):541;1978; Circulation 58(4):663;1978; J Pharmacol Exp Ther 184(1):?;1973; J Pharmacol Exp Ther 193(1):209;1975; J Pharmacol Exp Ther 1980;212(3):560; J Pharmacol Exp Ther 199(2):310;1976; J Pharmacol Exp Ther 204(2):294;1978; J Pharmacol Exp Ther 207(2):304;1978; Res Commun Chem Pathol Pharmacol 1979;25(2):227
4-hydroxypropranolol  10476-53-6 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-1-naphthalenol  Propranolol/*analogs & derivatives. Br J Pharmacol 43(1):222;1971; J Chromatogr 114(2):351;1975; J Chromatogr 145(3):429;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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